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Protein

Protein NRT1/ PTR FAMILY 5.2

Gene

NPF5.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Peptide transporter involved in stress tolerance in seeds during germination and in defense against virulent bacterial pathogens.2 Publications

GO - Molecular functioni

  • dipeptide transporter activity Source: TAIR
  • transmembrane transporter activity Source: InterPro
  • tripeptide transporter activity Source: TAIR

GO - Biological processi

  • defense response to bacterium Source: TAIR
  • dipeptide transport Source: TAIR
  • hyperosmotic salinity response Source: TAIR
  • response to abscisic acid Source: TAIR
  • response to histidine Source: TAIR
  • response to jasmonic acid Source: TAIR
  • response to leucine Source: TAIR
  • response to phenylalanine Source: TAIR
  • response to salicylic acid Source: TAIR
  • response to wounding Source: TAIR
  • tripeptide transport Source: TAIR

Enzyme and pathway databases

ReactomeiR-ATH-427975 Proton/oligopeptide cotransporters
R-ATH-6798695 Neutrophil degranulation

Protein family/group databases

TCDBi2.A.17.3.4 the proton-dependent oligopeptide transporter (pot/ptr) family

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NRT1/ PTR FAMILY 5.2
Short name:
AtNPF5.2
Alternative name(s):
Peptide transporter PTR3-A
Short name:
AtPTR3
Gene namesi
Name:NPF5.2
Synonyms:PTR3-A
Ordered Locus Names:At5g46050
ORF Names:MCL19.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G46050
TAIRilocus:2161438 AT5G46050

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei77 – 97HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei141 – 161HelicalSequence analysisAdd BLAST21
Transmembranei189 – 209HelicalSequence analysisAdd BLAST21
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Transmembranei334 – 354HelicalSequence analysisAdd BLAST21
Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Transmembranei408 – 428HelicalSequence analysisAdd BLAST21
Transmembranei452 – 472HelicalSequence analysisAdd BLAST21
Transmembranei493 – 515HelicalSequence analysisAdd BLAST23
Transmembranei538 – 558HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003001001 – 582Protein NRT1/ PTR FAMILY 5.2Add BLAST582

Proteomic databases

PaxDbiQ9FNL7
PRIDEiQ9FNL7

PTM databases

iPTMnetiQ9FNL7

Expressioni

Tissue specificityi

Expressed in roots. Detected in shoots, leaves and flowers.1 Publication

Inductioni

By wounding, salicylic acid, abscisic acid, methyl jasmonate, salt treatment and amino acids histidine, leucine and phenylalanine. No induction by glutamic acid, methionine or tryptophan.2 Publications

Gene expression databases

ExpressionAtlasiQ9FNL7 baseline and differential
GenevisibleiQ9FNL7 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G46050.1

Structurei

3D structure databases

ProteinModelPortaliQ9FNL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1237 Eukaryota
COG3104 LUCA
HOGENOMiHOG000237400
InParanoidiQ9FNL7
OMAiWNYGFVA
OrthoDBiEOG093607P9
PhylomeDBiQ9FNL7

Family and domain databases

InterProiView protein in InterPro
IPR036259 MFS_trans_sf
IPR000109 POT_fam
PANTHERiPTHR11654 PTHR11654, 1 hit
PfamiView protein in Pfam
PF00854 PTR2, 1 hit
SUPFAMiSSF103473 SSF103473, 2 hits

Sequencei

Sequence statusi: Complete.

Q9FNL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVEEVGDDY TKDGTVDLQG NPVRRSIRGR WKACSFVVVY EVFERMAYYG
60 70 80 90 100
ISSNLFIYMT TKLHQGTVKS SNNVTNWVGT SWLTPILGAY VGDALLGRYI
110 120 130 140 150
TFVISCAIYF SGMMVLTLSV TIPGIKPPEC STTNVENCEK ASVLQLAVFF
160 170 180 190 200
GALYTLAIGT GGTKPNISTI GADQFDVFDP KEKTQKLSFF NWWMFSIFFG
210 220 230 240 250
TLFANTVLVY VQDNVGWTLG YGLPTLGLAI SITIFLLGTP FYRHKLPTGS
260 270 280 290 300
PFTKMARVIV ASFRKANAPM THDITSFHEL PSLEYERKGA FPIHPTPSLR
310 320 330 340 350
FLDRASLKTG TNHKWNLCTT TEVEETKQML RMLPVLFITF VPSMMLAQIN
360 370 380 390 400
TLFVKQGTTL DRKVTGSFSI PPASLSGFVT LSMLISIVLY DRVFVKITRK
410 420 430 440 450
FTGNPRGITL LQRMGIGLIF HILIMIVASV TERYRLKVAA DHGLIHQTGV
460 470 480 490 500
KLPLTIFALL PQFVLMGMAD SFLEVAKLEF FYDQAPESMK SLGTSYSTTS
510 520 530 540 550
LAIGNFMSSF LLSTVSEITK KRGRGWILNN LNESRLDYYY LFFAVLNLVN
560 570 580
FVLFLVVVKF YVYRAEVTDS VDVKEVEMKE TE
Length:582
Mass (Da):65,271
Last modified:March 1, 2001 - v1
Checksum:iA9FCA16346CBAC60
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti552V → I in AAL36413 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006698 Genomic DNA Translation: BAB08250.1
CP002688 Genomic DNA Translation: AED95332.1
AY150511 mRNA Translation: AAN13027.1
AY064057 mRNA Translation: AAL36413.1
RefSeqiNP_199417.1, NM_123973.4
UniGeneiAt.27086

Genome annotation databases

EnsemblPlantsiAT5G46050.1; AT5G46050.1; AT5G46050
GeneIDi834646
GrameneiAT5G46050.1; AT5G46050.1; AT5G46050
KEGGiath:AT5G46050

Similar proteinsi

Entry informationi

Entry nameiPTR3_ARATH
AccessioniPrimary (citable) accession number: Q9FNL7
Secondary accession number(s): Q8VZK3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2001
Last modified: April 25, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health