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Protein

Probable CCR4-associated factor 1 homolog 11

Gene

CAF1-11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity).By similarity

Catalytic activityi

Exonucleolytic cleavage of poly(A) to 5'-AMP.

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi42 – 421Divalent metal cation; catalyticBy similarity
Metal bindingi44 – 441Divalent metal cation; catalyticBy similarity
Metal bindingi172 – 1721Divalent metal cation; catalyticBy similarity
Metal bindingi244 – 2441Divalent metal cation; catalyticBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable CCR4-associated factor 1 homolog 11 (EC:3.1.13.4)
Gene namesi
Name:CAF1-11
Ordered Locus Names:At5g22250
ORF Names:T6G21.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G22250.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 278278Probable CCR4-associated factor 1 homolog 11PRO_0000371561Add
BLAST

Proteomic databases

PaxDbiQ9FMS6.
PRIDEiQ9FMS6.

PTM databases

iPTMnetiQ9FMS6.

Expressioni

Gene expression databases

GenevisibleiQ9FMS6. AT.

Interactioni

Subunit structurei

Component of the CCR4-NOT complex, at least composed of CRR4 and CAF1 proteins.By similarity

Protein-protein interaction databases

STRINGi3702.AT5G22250.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FMS6.
SMRiQ9FMS6. Positions 14-275.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CAF1 family.Curated

Phylogenomic databases

eggNOGiKOG0304. Eukaryota.
COG5228. LUCA.
HOGENOMiHOG000173077.
InParanoidiQ9FMS6.
KOiK12581.
OMAiREFDPRV.
PhylomeDBiQ9FMS6.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006941. RNase_CAF1.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF04857. CAF1. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9FMS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKSEADLSD VIVIRDVWAY NLESEFDLIR GIVEDYPFIS MDTEFPGVIY
60 70 80 90 100
KADLDVLRRG NPNYLYNLLK SNVDALSLIQ VGLTLSDADG NLPDLGGQKN
110 120 130 140 150
RRYIWEFNFR DFDVERDPHA PDSIELLRRH GIDFERNRRE GVESERFAEL
160 170 180 190 200
MMSSGLICNE SVSWVTFHSA YDFGYLVKIL TRRQLPVALR EFLGLLRAFF
210 220 230 240 250
GDRVYDVKHI MRFCEQRLYG GLDRVARSLE VNRAVGKCHQ AGSDSLLTWQ
260 270
AFQRMRDLYF VEDGAEKHAG VLYGLEVF
Length:278
Mass (Da):32,169
Last modified:March 1, 2001 - v1
Checksum:i468FF7C2AFE33DDE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007651 Genomic DNA. Translation: BAB08323.1.
CP002688 Genomic DNA. Translation: AED93001.1.
AY063985 mRNA. Translation: AAL36341.1.
BT001962 mRNA. Translation: AAN71961.1.
RefSeqiNP_197617.1. NM_122130.3.
UniGeneiAt.27479.

Genome annotation databases

EnsemblPlantsiAT5G22250.1; AT5G22250.1; AT5G22250.
GeneIDi832285.
GrameneiAT5G22250.1; AT5G22250.1; AT5G22250.
KEGGiath:AT5G22250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007651 Genomic DNA. Translation: BAB08323.1.
CP002688 Genomic DNA. Translation: AED93001.1.
AY063985 mRNA. Translation: AAL36341.1.
BT001962 mRNA. Translation: AAN71961.1.
RefSeqiNP_197617.1. NM_122130.3.
UniGeneiAt.27479.

3D structure databases

ProteinModelPortaliQ9FMS6.
SMRiQ9FMS6. Positions 14-275.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G22250.1.

PTM databases

iPTMnetiQ9FMS6.

Proteomic databases

PaxDbiQ9FMS6.
PRIDEiQ9FMS6.

Protocols and materials databases

DNASUi832285.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G22250.1; AT5G22250.1; AT5G22250.
GeneIDi832285.
GrameneiAT5G22250.1; AT5G22250.1; AT5G22250.
KEGGiath:AT5G22250.

Organism-specific databases

TAIRiAT5G22250.

Phylogenomic databases

eggNOGiKOG0304. Eukaryota.
COG5228. LUCA.
HOGENOMiHOG000173077.
InParanoidiQ9FMS6.
KOiK12581.
OMAiREFDPRV.
PhylomeDBiQ9FMS6.

Miscellaneous databases

PROiQ9FMS6.

Gene expression databases

GenevisibleiQ9FMS6. AT.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006941. RNase_CAF1.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF04857. CAF1. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence features of the regions of 1,191,918 bp covered by seventeen physically assigned P1 clones."
    Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N., Tabata S.
    DNA Res. 4:401-414(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.

Entry informationi

Entry nameiCAF1K_ARATH
AccessioniPrimary (citable) accession number: Q9FMS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: March 1, 2001
Last modified: May 11, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.