SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9FLF7

- MYST1_ARATH

UniProt

Q9FLF7 - MYST1_ARATH

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable MYST-like histone acetyltransferase 1

Gene
HAG4, At5g64610, MUB3.13
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Histone acetyltransferase which may be involved in transcriptional activation By similarity.

Catalytic activityi

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei269 – 2691 By similarity
Active sitei311 – 3111Nucleophile By similarity
Binding sitei314 – 3141Acetyl-CoA By similarity
Binding sitei349 – 3491Acetyl-CoA By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri203 – 22523C2HC-typeAdd
BLAST

GO - Molecular functioni

  1. histone acetyltransferase activity Source: TAIR
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. DNA repair Source: TAIR
  2. histone acetylation Source: GOC
  3. regulation of transcription, DNA-templated Source: UniProtKB-KW
  4. response to UV-B Source: TAIR
  5. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Acyltransferase, Chromatin regulator, Transferase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciARA:AT5G64610-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable MYST-like histone acetyltransferase 1 (EC:2.3.1.48)
Gene namesi
Name:HAG4
Ordered Locus Names:At5g64610
ORF Names:MUB3.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G64610.

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Probable MYST-like histone acetyltransferase 1PRO_0000238464Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei269 – 2691N6-acetyllysine; by autocatalysis By similarity

Post-translational modificationi

Autoacetylation at Lys-269 is required for proper function By similarity.

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9FLF7.
PRIDEiQ9FLF7.

Expressioni

Gene expression databases

GenevestigatoriQ9FLF7.

Interactioni

Protein-protein interaction databases

BioGridi21824. 1 interaction.
IntActiQ9FLF7. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9FLF7.
SMRiQ9FLF7. Positions 172-440.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini74 – 13360ChromoAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni319 – 3257Acetyl-CoA binding By similarity

Sequence similaritiesi

Belongs to the MYST (SAS/MOZ) family.
Contains 1 chromo domain.

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri203 – 22523C2HC-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG5027.
HOGENOMiHOG000182457.
InParanoidiQ9FLF7.
KOiK11308.
OMAiRRLDEWI.
PhylomeDBiQ9FLF7.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo_domain/shadow.
IPR016197. Chromodomain-like.
IPR002717. MOZ_SAS.
IPR025995. Tudor-knot.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
SUPFAMiSSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9FLF7-1 [UniParc]FASTAAdd to Basket

« Hide

MGSSADTETA MIIATPASNH NNPATNGGDA NQNHTSGAIL ALTNSESDAS    50
KKRRMGVLPL EVGTRVMCQW RDGKYHPVKV IERRKNYNGG HNDYEYYVHY 100
TEFNRRLDEW IKLEQLDLDS VECALDEKVE DKVTSLKMTR HQKRKIDETH 150
VEGHEELDAA SLREHEEFTK VKNIATIELG KYEIETWYFS PFPPEYNDCV 200
KLFFCEFCLS FMKRKEQLQR HMRKCDLKHP PGDEIYRSST LSMFEVDGKK 250
NKVYAQNLCY LAKLFLDHKT LYYDVDLFLF YILCECDDRG CHMVGYFSKE 300
KHSEEAYNLA CILTLPPYQR KGYGKFLIAF SYELSKKEGK VGTPERPLSD 350
LGLVSYRGYW TRILLDILKK HKGNISIKEL SDMTAIKAED ILSTLQSLEL 400
IQYRKGQHVI CADPKVLDRH LKAAGRGGLD VDVSKMIWTP YKEQS 445
Length:445
Mass (Da):51,438
Last modified:March 1, 2001 - v1
Checksum:iF2243F5808ADE207
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB010076 Genomic DNA. Translation: BAB11428.1.
CP002688 Genomic DNA. Translation: AED97926.1.
AY099684 mRNA. Translation: AAM20535.1.
BT000277 mRNA. Translation: AAN15596.1.
RefSeqiNP_201266.1. NM_125857.2.
UniGeneiAt.28949.
At.49220.

Genome annotation databases

EnsemblPlantsiAT5G64610.1; AT5G64610.1; AT5G64610.
GeneIDi836582.
KEGGiath:AT5G64610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB010076 Genomic DNA. Translation: BAB11428.1 .
CP002688 Genomic DNA. Translation: AED97926.1 .
AY099684 mRNA. Translation: AAM20535.1 .
BT000277 mRNA. Translation: AAN15596.1 .
RefSeqi NP_201266.1. NM_125857.2.
UniGenei At.28949.
At.49220.

3D structure databases

ProteinModelPortali Q9FLF7.
SMRi Q9FLF7. Positions 172-440.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 21824. 1 interaction.
IntActi Q9FLF7. 1 interaction.

Proteomic databases

PaxDbi Q9FLF7.
PRIDEi Q9FLF7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G64610.1 ; AT5G64610.1 ; AT5G64610 .
GeneIDi 836582.
KEGGi ath:AT5G64610.

Organism-specific databases

TAIRi AT5G64610.

Phylogenomic databases

eggNOGi COG5027.
HOGENOMi HOG000182457.
InParanoidi Q9FLF7.
KOi K11308.
OMAi RRLDEWI.
PhylomeDBi Q9FLF7.

Enzyme and pathway databases

BioCyci ARA:AT5G64610-MONOMER.

Gene expression databases

Genevestigatori Q9FLF7.

Family and domain databases

Gene3Di 3.40.630.30. 1 hit.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo_domain/shadow.
IPR016197. Chromodomain-like.
IPR002717. MOZ_SAS.
IPR025995. Tudor-knot.
IPR015880. Znf_C2H2-like.
[Graphical view ]
Pfami PF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view ]
SMARTi SM00298. CHROMO. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
SUPFAMi SSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence features of the regions of 1,456,315 bp covered by nineteen physically assigned P1 and TAC clones."
    Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N., Tabata S.
    DNA Res. 5:41-54(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes."
    Pandey R., Mueller A., Napoli C.A., Selinger D.A., Pikaard C.S., Richards E.J., Bender J., Mount D.W., Jorgensen R.A.
    Nucleic Acids Res. 30:5036-5055(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION, NOMENCLATURE.

Entry informationi

Entry nameiMYST1_ARATH
AccessioniPrimary (citable) accession number: Q9FLF7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi