Reviewed,
UniProtKB/Swiss-Prot Q9FLC0 (PER52_ARATH)
Last modified
June 16, 2009.
Version 67.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Peroxidase 52 Short name=Atperox P52 EC=1.11.1.7 Alternative name(s): ATP49 | ||||||||
| Gene names |
| ||||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 324 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue. |
| Catalytic activity | Donor + H2O2 = oxidized donor + 2 H2O. |
| Cofactor | Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity. |
| Subcellular location | Secreted By similarity. |
| Miscellaneous | There are 73 peroxidase genes in A.thaliana. |
| Sequence similarities | Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Hydrogen peroxide |
| Cellular component | Secreted |
| Domain | Signal |
| Ligand | Calcium Heme Iron Metal-binding |
| Molecular function | Oxidoreductase Peroxidase |
| PTM | Disulfide bond Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | apoplast Inferred from direct assay. Source: TAIR cell wallInferred from direct assay. Source: TAIR |
| Molecular function | calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activityInferred from electronic annotation. Source: InterPro heme bindingInferred from electronic annotation. Source: InterPro peroxidase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 20 | 20 | Potential | ||||||||
| Chain | 21 – 324 | 304 | Peroxidase 52 | PRO_0000023717 | |||||||
Sites | |||||||||||
| Active site | 70 | 1 | Proton acceptor By similarity | ||||||||
| Metal binding | 71 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 74 | 1 | Calcium 1; via carbonyl oxygen By similarity | ||||||||
| Metal binding | 76 | 1 | Calcium 1; via carbonyl oxygen By similarity | ||||||||
| Metal binding | 78 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 80 | 1 | Calcium 1 By similarity | ||||||||
| Metal binding | 197 | 1 | Iron (heme axial ligand) By similarity | ||||||||
| Metal binding | 198 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 244 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 247 | 1 | Calcium 2 By similarity | ||||||||
| Metal binding | 252 | 1 | Calcium 2 By similarity | ||||||||
| Binding site | 167 | 1 | Substrate; via carbonyl oxygen By similarity | ||||||||
| Site | 66 | 1 | Transition state stabilizer By similarity | ||||||||
Amino acid modifications | |||||||||||
| Glycosylation | 213 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Disulfide bond | 39 ↔ 119 | By similarity | |||||||||
| Disulfide bond | 72 ↔ 77 | By similarity | |||||||||
| Disulfide bond | 125 ↔ 320 | By similarity | |||||||||
| Disulfide bond | 204 ↔ 229 | By similarity | |||||||||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones." Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S. DNA Res. 5:131-145(1998) [PubMed: 9679202] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [2] | "Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R.Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [3] | "Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia. |
Cross-references
Sequence databases | |
|---|---|
| AB010692 Genomic DNA. Translation: BAB09977.1. AY065270 mRNA. Translation: AAL38746.1. | |
| IPI | IPI00527468. |
| RefSeq | NP_196153.1. |
| UniGene | At.28537 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1SCH based on UniProtKB P22195. |
| ModBase | Search... |
Protein family/group databases | |
| PeroxiBase | 218. AtPrx52. |
Proteomic databases | |
| PRIDE | Q9FLC0. |
Genome annotation databases | |
| GeneID | 830416. |
| GenomeReviews | Gene locus AT5G05340 in contig BA000015_GR. |
| KEGG | ath:AT5G05340. |
| NMPDR | fig|3702.1.peg.22639. |
Organism-specific databases | |
| GeneFarm | 1905. 61. |
| TAIR | At5g05340. |
Phylogenomic databases | |
| OMA | Q9FLC0. TNFRARI. |
Enzyme and pathway databases | |
| BRENDA | 1.11.1.7. 302. |
Gene expression databases | |
| ArrayExpress | Q9FLC0. |
| GermOnline | AT5G05340. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view] |
| Pfam | PF00141. peroxidase. 1 hit. [Graphical view] |
| PRINTS | PR00458. PEROXIDASE. PR00461. PLPEROXIDASE. |
| PROSITE | PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PER52_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9FLC0 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


