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Q9FLC0 (PER52_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peroxidase 52
Short name=Atperox P52
EC=1.11.1.7
Alternative name(s):
ATP49
Gene names
Name:PER52
Synonyms:P52
Ordered Locus Names:At5g05340
ORF Names:K18I23.14
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Catalytic activity

2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Binds 2 calcium ions per subunit By similarity.

Subcellular location

Secreted By similarity.

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Sequence similarities

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

Ontologies

Keywords
   Biological processHydrogen peroxide
   Cellular componentSecreted
   DomainSignal
   LigandCalcium
Heme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processhydrogen peroxide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentapoplast

Inferred from direct assay. Source: TAIR

cell wall

Inferred from direct assay. Source: TAIR

cytosol

Inferred from direct assay. Source: TAIR

   Molecular functionheme binding

Inferred from electronic annotation. Source: InterPro

peroxidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

protein binding

Inferred from physical interaction. Source: TAIR

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 324304Peroxidase 52
PRO_0000023717

Sites

Active site701Proton acceptor By similarity
Metal binding711Calcium 1 By similarity
Metal binding741Calcium 1; via carbonyl oxygen By similarity
Metal binding761Calcium 1; via carbonyl oxygen By similarity
Metal binding781Calcium 1 By similarity
Metal binding801Calcium 1 By similarity
Metal binding1971Iron (heme axial ligand) By similarity
Metal binding1981Calcium 2 By similarity
Metal binding2441Calcium 2 By similarity
Metal binding2471Calcium 2 By similarity
Metal binding2521Calcium 2 By similarity
Binding site1671Substrate; via carbonyl oxygen By similarity
Site661Transition state stabilizer By similarity

Amino acid modifications

Glycosylation2131N-linked (GlcNAc...) Potential
Disulfide bond39 ↔ 119 By similarity
Disulfide bond72 ↔ 77 By similarity
Disulfide bond125 ↔ 320 By similarity
Disulfide bond204 ↔ 229 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9FLC0 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: F891CD4EEEEC5AD4

FASTA32434,215
        10         20         30         40         50         60 
MASNKLISIL VLVVTLLLQG DNNYVVEAQL TTNFYSTSCP NLLSTVQTAV KSAVNSEARM 

        70         80         90        100        110        120 
GASILRLFFH DCFVNGCDGS ILLDDTSSFT GEQNAAPNRN SARGFNVIDN IKSAVEKACP 

       130        140        150        160        170        180 
GVVSCADILA IAARDSVVAL GGPNWNVKVG RRDARTASQA AANSNIPAPT SSLSQLISSF 

       190        200        210        220        230        240 
SAVGLSTRDM VALSGAHTIG QSRCTNFRAR IYNETNINAA FATTRQRTCP RASGSGDGNL 

       250        260        270        280        290        300 
APLDVTTAAS FDNNYFKNLM TQRGLLHSDQ VLFNGGSTDS IVRGYSNNPS SFNSDFTAAM 

       310        320 
IKMGDISPLT GSSGEIRKVC GRTN

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones."
Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S.
DNA Res. 5:131-145(1998) [PubMed: 9679202] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana."
Tognolli M., Penel C., Greppin H., Simon P.
Gene 288:129-138(2002) [PubMed: 12034502] [Abstract]
Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE.
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB010692 Genomic DNA. Translation: BAB09977.1.
CP002688 Genomic DNA. Translation: AED90861.1.
AY065270 mRNA. Translation: AAL38746.1.
IPIIPI00527468.
RefSeqNP_196153.1. NM_120616.2.
UniGeneAt.28537.

3D structure databases

ProteinModelPortalQ9FLC0.
SMRQ9FLC0. Positions 29-324.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9FLC0. 1 interaction.
STRINGQ9FLC0.

Protein family/group databases

PeroxiBase218. AtPrx52.

Proteomic databases

PRIDEQ9FLC0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G05340.1; AT5G05340.1; AT5G05340.
GeneID830416.
GenomeReviewsGene locus AT5G05340 in contig BA000015_GR.
KEGGath:AT5G05340.
NMPDRfig|3702.1.peg.22639.

Organism-specific databases

GeneFarm1905. 61.
TAIRAt5g05340.

Phylogenomic databases

GeneTreeEPGT00070000028277.
HOGENOMHBG597790.
InParanoidQ9FLC0.
OMATNFRARI.
PhylomeDBQ9FLC0.
ProtClustDBCLSN2916362.

Gene expression databases

ArrayExpressQ9FLC0.
GenevestigatorQ9FLC0.
GermOnlineAT5G05340. Arabidopsis thaliana.

Family and domain databases

InterProIPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR000823. Peroxidase_pln.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
KOK00430.
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00458. PEROXIDASE.
PR00461. PLPEROXIDASE.
SUPFAMSSF48113. Peroxidase_super. 1 hit.
PROSITEPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePER52_ARATH
AccessionPrimary (citable) accession number: Q9FLC0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: March 1, 2001
Last modified: December 14, 2011
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

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