Peroxidase 63 precursor - Arabidopsis thaliana (Mouse-ear cress)

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Q9FL16 (PER63_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 86. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Peroxidase 63
Short name=Atperox P63
EC=1.11.1.7

Alternative name(s):
ATP26a

Gene names

Name:	PER63
Synonyms:	P63
Ordered Locus Names:	At5g40150
ORF Names:	MSN9.5, MSN9.50

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Removal of H₂O₂, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Catalytic activity	2 phenolic donor + H₂O₂ = 2 phenoxyl radical of the donor + 2 H₂O.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity.
Subcellular location	Secreted By similarity.
Miscellaneous	There are 73 peroxidase genes in A.thaliana.
Sequence similarities	Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Secreted
Domain	Signal
Ligand	Calcium Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 27

Potential

Chain

28 – 328

301

Peroxidase 63

PRO_0000023728

Sites

Active site

Proton acceptor By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1 By similarity

Metal binding

200

Iron (heme axial ligand) By similarity

Metal binding

201

Calcium 2 By similarity

Metal binding

248

Calcium 2 By similarity

Metal binding

251

Calcium 2 By similarity

Metal binding

256

Calcium 2 By similarity

Binding site

170

Substrate; via carbonyl oxygen By similarity

Site

Transition state stabilizer By similarity

Amino acid modifications

Glycosylation

217

N-linked (GlcNAc...) Potential

Glycosylation

218

N-linked (GlcNAc...) Potential

Disulfide bond

41 ↔ 122

By similarity

Disulfide bond

74 ↔ 79

By similarity

Disulfide bond

128 ↔ 324

By similarity

Disulfide bond

207 ↔ 234

By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q9FL16 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 2171431964F09048
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FASTA

328

36,120

        10         20         30         40         50         60 
MAEQSQLKNL TIILLLLCLS FQSLSFAAES HLTVDFYSKS CPKFLDIIRE TITNKQISTP 

        70         80         90        100        110        120 
TTAAAALRLF FHDCFPNGCD ASVLVSSTAF NTAERDSSIN LSLPGDGFDV VIRAKTALEL 

       130        140        150        160        170        180 
ACPNTVSCSD IIAVAVRDLL VTVGGPYYEI SLGRRDSRTS KSSLVSDLLP LPSMQISKLI 

       190        200        210        220        230        240 
DQFSSRGFSV QEMVALSGAH TIGFSHCKEF TNRVNPNNST GYNPRFAVAL KKACSNSKND 

       250        260        270        280        290        300 
PTISVFNDVM TPNKFDNMYF QNIPKGLGLL ESDHGLFSDP RTRPFVELYA RDQSRFFNDF 

       310        320 
AGAMQKLSLH GVLTGRRGEI RRRCDAIN

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones." Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S. DNA Res. 5:131-145(1998) [PubMed: 9679202] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Functional annotation of a full-length Arabidopsis cDNA collection." Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K. Science 296:141-145(2002) [PubMed: 11910074] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"From expressed sequence tags to structure, function, evolution and expression of 28 ER-targeted Arabidopsis peroxidases." Welinder K.G., Jespersen H.M., Kjaersgaard I.V.H., Justesen A.F., Oestergaard L., Abelskov A.K., Jensen R.B., Hansen L.N., Rasmussen S.K. Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 53-328. Strain: cv. Columbia.
[5]	"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB010699 Genomic DNA. Translation: BAB10896.1. CP002688 Genomic DNA. Translation: AED94513.1. AK118632 mRNA. Translation: BAC43229.1. Y11791 mRNA. Translation: CAA72487.1.
IPI	IPI00535868.
RefSeq	NP_198831.1. NM_123378.2.
UniGene	At.88.
3D structure databases
ProteinModelPortal	Q9FL16.
SMR	Q9FL16. Positions 31-328.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9FL16.
Protein family/group databases
PeroxiBase	229. AtPrx63.
Proteomic databases
PRIDE	Q9FL16.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G40150.1; AT5G40150.1; AT5G40150.
GeneID	834012.
GenomeReviews	Gene locus AT5G40150 in contig BA000015_GR.
KEGG	ath:AT5G40150.
NMPDR	fig\|3702.1.peg.25714.
Organism-specific databases
GeneFarm	1922. 61.
TAIR	At5g40150.
Phylogenomic databases
eggNOG	COG0376.
GeneTree	EPGT00050000003677.
HOGENOM	HBG597790.
InParanoid	Q9FL16.
OMA	FVELYAR.
PhylomeDB	Q9FL16.
ProtClustDB	CLSN2685204.
Gene expression databases
ArrayExpress	Q9FL16.
Genevestigator	Q9FL16.
GermOnline	AT5G40150. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR010255. Haem_peroxidase. IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. IPR019794. Peroxidases_AS. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view]
KO	K00430.
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00458. PEROXIDASE. PR00461. PLPEROXIDASE.
SUPFAM	SSF48113. Peroxidase_super. 1 hit.
PROSITE	PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PER63_ARATH

Accession

Primary (citable) accession number: Q9FL16
Secondary accession number(s): P93726

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2002
Last sequence update:	March 1, 2001
Last modified:	November 16, 2011
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Sites

Amino acid modifications

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents