Q9FKX4 (P2C79_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 79
Short name=AtPP2C79
EC=3.1.3.16

Gene names

Ordered Locus Names:	At5g66080
ORF Names:	K2A18.16

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Domain	Signal
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 385	367	Probable protein phosphatase 2C 79		PRO_0000367998
Regions
	Domain	82 – 328	247	PP2C-like
Sites
	Metal binding	87	1	Manganese 1 By similarity
	Metal binding	87	1	Manganese 2 By similarity
	Metal binding	88	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	288	1	Manganese 2 By similarity
	Metal binding	347	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9FKX4 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: C28A2ABB7F243B2D	FASTA	385	42,963
	10 20 30 40 50 60 MLSLFFNFLT SCLWPSSSTT SHTYSDSKGK QDGLLWYKDS AHHLFGDFSM AVVQANNLLE 70 80 90 100 110 120 DQSQVESGPL TTLSSSGPYG TFVGVYDGHG GPETSRFVND HLFHHLKRFA AEQDSMSVDV 130 140 150 160 170 180 IRKAYEATEE GFLGVVAKQW AVKPHIAAVG SCCLIGVVCD GKLYVANVGD SRAVLGKVIK 190 200 210 220 230 240 ATGEVNALQL SAEHNVSIES VRQEMHSLHP DDSHIVVLKH NVWRVKGIIQ VSRSIGDVYL 250 260 270 280 290 300 KKSEFNKEPL YTKYRLREPM KRPILSWEPS ITVHDLQPDD QFLIFASDGL WEQLSNQEAV 310 320 330 340 350 360 EIVQNHPRNG IARRLVKAAL QEAAKKREMR YSDLNKIERG VRRHFHDDIT VVVLFLDTNL 370 380 LSRASSLKTP SVSIRGGGIT LPKKL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones." Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S. DNA Res. 5:131-145(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB011474 Genomic DNA. Translation: BAB10413.1. CP002688 Genomic DNA. Translation: AED98157.1. AY062587 mRNA. Translation: AAL32665.1. BT001229 mRNA. Translation: AAN65116.1.
IPI	IPI00522788.
RefSeq	NP_201409.1. NM_126006.3.
UniGene	At.27294.
3D structure databases
ProteinModelPortal	Q9FKX4.
SMR	Q9FKX4. Positions 80-356.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-8390450.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G66080.1; AT5G66080.1; AT5G66080.
GeneID	836740.
KEGG	ath:AT5G66080.
Organism-specific databases
TAIR	At5g66080.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000238703.
InParanoid	Q9FKX4.
OMA	ETARFIN.
PhylomeDB	Q9FKX4.
ProtClustDB	CLSN2916384.
Gene expression databases
Genevestigator	Q9FKX4.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C79_ARATH

Accession

Primary (citable) accession number: Q9FKX4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 1, 2001
Last modified:	May 29, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program