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Q9FKX4

- P2C79_ARATH

UniProt

Q9FKX4 - P2C79_ARATH

Protein

Probable protein phosphatase 2C 79

Gene

At5g66080

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi87 – 871Manganese 1By similarity
    Metal bindingi87 – 871Manganese 2By similarity
    Metal bindingi88 – 881Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi288 – 2881Manganese 2By similarity
    Metal bindingi347 – 3471Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G66080-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 79 (EC:3.1.3.16)
    Short name:
    AtPP2C79
    Gene namesi
    Ordered Locus Names:At5g66080
    ORF Names:K2A18.16
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G66080.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 385367Probable protein phosphatase 2C 79PRO_0000367998Add
    BLAST

    Proteomic databases

    PRIDEiQ9FKX4.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9FKX4.

    Interactioni

    Protein-protein interaction databases

    BioGridi21982. 1 interaction.
    IntActiQ9FKX4. 1 interaction.
    MINTiMINT-8390450.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FKX4.
    SMRiQ9FKX4. Positions 80-356.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini82 – 328247PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000238703.
    InParanoidiQ9FKX4.
    OMAiWAVKPHI.
    PhylomeDBiQ9FKX4.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9FKX4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSLFFNFLT SCLWPSSSTT SHTYSDSKGK QDGLLWYKDS AHHLFGDFSM    50
    AVVQANNLLE DQSQVESGPL TTLSSSGPYG TFVGVYDGHG GPETSRFVND 100
    HLFHHLKRFA AEQDSMSVDV IRKAYEATEE GFLGVVAKQW AVKPHIAAVG 150
    SCCLIGVVCD GKLYVANVGD SRAVLGKVIK ATGEVNALQL SAEHNVSIES 200
    VRQEMHSLHP DDSHIVVLKH NVWRVKGIIQ VSRSIGDVYL KKSEFNKEPL 250
    YTKYRLREPM KRPILSWEPS ITVHDLQPDD QFLIFASDGL WEQLSNQEAV 300
    EIVQNHPRNG IARRLVKAAL QEAAKKREMR YSDLNKIERG VRRHFHDDIT 350
    VVVLFLDTNL LSRASSLKTP SVSIRGGGIT LPKKL 385
    Length:385
    Mass (Da):42,963
    Last modified:March 1, 2001 - v1
    Checksum:iC28A2ABB7F243B2D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB011474 Genomic DNA. Translation: BAB10413.1.
    CP002688 Genomic DNA. Translation: AED98157.1.
    AY062587 mRNA. Translation: AAL32665.1.
    BT001229 mRNA. Translation: AAN65116.1.
    RefSeqiNP_201409.1. NM_126006.3.
    UniGeneiAt.27294.

    Genome annotation databases

    EnsemblPlantsiAT5G66080.1; AT5G66080.1; AT5G66080.
    GeneIDi836740.
    KEGGiath:AT5G66080.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB011474 Genomic DNA. Translation: BAB10413.1 .
    CP002688 Genomic DNA. Translation: AED98157.1 .
    AY062587 mRNA. Translation: AAL32665.1 .
    BT001229 mRNA. Translation: AAN65116.1 .
    RefSeqi NP_201409.1. NM_126006.3.
    UniGenei At.27294.

    3D structure databases

    ProteinModelPortali Q9FKX4.
    SMRi Q9FKX4. Positions 80-356.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 21982. 1 interaction.
    IntActi Q9FKX4. 1 interaction.
    MINTi MINT-8390450.

    Proteomic databases

    PRIDEi Q9FKX4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G66080.1 ; AT5G66080.1 ; AT5G66080 .
    GeneIDi 836740.
    KEGGi ath:AT5G66080.

    Organism-specific databases

    TAIRi AT5G66080.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000238703.
    InParanoidi Q9FKX4.
    OMAi WAVKPHI.
    PhylomeDBi Q9FKX4.

    Enzyme and pathway databases

    BioCyci ARA:AT5G66080-MONOMER.

    Gene expression databases

    Genevestigatori Q9FKX4.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones."
      Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S.
      DNA Res. 5:131-145(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C79_ARATH
    AccessioniPrimary (citable) accession number: Q9FKX4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3