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Q9FKT9 (NAS2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotianamine synthase 2

EC=2.5.1.43
Alternative name(s):
S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 2
Short name=AtNAS2
Gene names
Name:NAS2
Ordered Locus Names:At5g56080
ORF Names:MDA7.14
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length320 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Synthesizes nicotianamine, a polyamine which serves as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.

Catalytic activity

3 S-adenosyl-L-methionine = 3 S-methyl-5'-thioadenosine + nicotianamine.

Sequence similarities

Belongs to the nicotianamine synthase (NAS)-like family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 320320Nicotianamine synthase 2
PRO_0000212701

Experimental info

Sequence conflict41E → Q in BAA74590. Ref.1
Sequence conflict3161Y → F in BAA74590. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9FKT9 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 0F089819D3C05FCA

FASTA32035,679
        10         20         30         40         50         60 
MACENNLVVK QIMDLYNQIS NLESLKPSKN VDTLFRQLVS TCLPTDTNID VTEIHDEKVK 

        70         80         90        100        110        120 
DMRSHLIKLC GEAEGYLEQH FSAILGSFED NPLNHLHIFP YYNNYLKLGK LEFDLLSQHT 

       130        140        150        160        170        180 
THVPTKVAFI GSGPMPLTSI VLAKFHLPNT TFHNFDIDSH ANTLASNLVS RDSDLSKRMI 

       190        200        210        220        230        240 
FHTTDVLNAK EGLDQYDVVF LAALVGMDKE SKVKAIEHLE KHMAPGAVVM LRSAHGLRAF 

       250        260        270        280        290        300 
LYPIVDSCDL KGFEVLTIYH PSDDVVNSVV IARKLGGSNG ARGSQIGRCV VMPCNCSKVH 

       310        320 
AILNNRGMEK NLIEEYSAIE 

« Hide

References

« Hide 'large scale' references
[1]"Cloning of nicotianamine synthase genes from Arabidopsis thaliana."
Suzuki K., Higuchi K., Nakanishi H., Nishizawa N.-K., Mori S.
Soil Sci. Plant Nutr. 45:993-1002(1999)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Columbia.
[2]"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones."
Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N., Tabata S.
DNA Res. 5:131-145(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Arabidopsis ORF clones."
Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB021935 Genomic DNA. Translation: BAA74590.1.
AB011476 Genomic DNA. Translation: BAB09290.1.
CP002688 Genomic DNA. Translation: AED96719.1.
BT030013 mRNA. Translation: ABN04751.1.
RefSeqNP_200419.1. NM_124990.1.
UniGeneAt.49799.

3D structure databases

ProteinModelPortalQ9FKT9.
SMRQ9FKT9. Positions 8-276.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G56080.1-P.

Proteomic databases

PaxDbQ9FKT9.
PRIDEQ9FKT9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G56080.1; AT5G56080.1; AT5G56080.
GeneID835707.
KEGGath:AT5G56080.

Organism-specific databases

TAIRAT5G56080.

Phylogenomic databases

eggNOGCOG0500.
HOGENOMHOG000025525.
InParanoidQ9FKT9.
KOK05953.
OMAMACENNL.
PhylomeDBQ9FKT9.
ProtClustDBPLN03075.

Enzyme and pathway databases

BioCycARA:AT5G56080-MONOMER.

Gene expression databases

GenevestigatorQ9FKT9.

Family and domain databases

InterProIPR004298. Nicotian_synth.
[Graphical view]
PfamPF03059. NAS. 1 hit.
[Graphical view]
PROSITEPS51142. NAS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNAS2_ARATH
AccessionPrimary (citable) accession number: Q9FKT9
Secondary accession number(s): A2RVM2, Q9ZWF7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 13, 2002
Last sequence update: March 1, 2001
Last modified: March 19, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names