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Protein

Membrin-12

Gene

MEMB12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-204005 COPII (Coat Protein 2) Mediated Vesicle Transport
R-ATH-5694530 Cargo concentration in the ER
R-ATH-6807878 COPI-mediated anterograde transport
R-ATH-6811438 Intra-Golgi traffic

Names & Taxonomyi

Protein namesi
Recommended name:
Membrin-12
Short name:
AtMEMB12
Alternative name(s):
Golgi SNAP receptor complex member 2-2
Gene namesi
Name:MEMB12
Ordered Locus Names:At5g50440
ORF Names:MXI22.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G50440
TAIRilocus:2177512 AT5G50440

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 197CytoplasmicSequence analysisAdd BLAST196
Transmembranei198 – 215Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST18
Topological domaini216 – 219VesicularSequence analysis4

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002125552 – 219Membrin-12Add BLAST218

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9FK28

PTM databases

iPTMnetiQ9FK28

Expressioni

Gene expression databases

ExpressionAtlasiQ9FK28 baseline and differential
GenevisibleiQ9FK28 AT

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi20358, 24 interactors
STRINGi3702.AT5G50440.1

Structurei

3D structure databases

ProteinModelPortaliQ9FK28
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GOSR2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3251 Eukaryota
ENOG4111M37 LUCA
HOGENOMiHOG000264938
InParanoidiQ9FK28
KOiK08496
OMAiTTNQETR
OrthoDBiEOG09360NTZ
PhylomeDBiQ9FK28

Family and domain databases

InterProiView protein in InterPro
IPR027027 GOSR2/Membrin/Bos1
PIRSFiPIRSF028865 Membrin-2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9FK28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGTVGGLS EVYSSAKRIL LRARNGIEKL ERFDSDPTDL ASSVKRDITE
60 70 80 90 100
VQSLCSNMDG LWRSIPVKSQ RDLWRRKSEQ VGEEAEYLNQ SLEKYMWRNQ
110 120 130 140 150
RKMLEAKERA DLLGRGSGEG AHILQIFDEE AQGMNSVKNS KRMLEDSFQS
160 170 180 190 200
GVAILSKYAE QRDRLKSAQR KALDVLNTVG LSNSVLRLIE RRNRVDTWIK
210
YAGMIATLVI LYLFIRWTR
Length:219
Mass (Da):25,105
Last modified:March 1, 2001 - v1
Checksum:i9885F002AF89B4EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012248 Genomic DNA Translation: BAB09463.1
CP002688 Genomic DNA Translation: AED95946.1
CP002688 Genomic DNA Translation: ANM68268.1
BT004999 mRNA Translation: AAO50532.1
RefSeqiNP_001330036.1, NM_001344893.1
NP_199855.1, NM_124426.5
UniGeneiAt.29730

Genome annotation databases

EnsemblPlantsiAT5G50440.1; AT5G50440.1; AT5G50440
AT5G50440.2; AT5G50440.2; AT5G50440
GeneIDi835112
GrameneiAT5G50440.1; AT5G50440.1; AT5G50440
AT5G50440.2; AT5G50440.2; AT5G50440
KEGGiath:AT5G50440

Similar proteinsi

Entry informationi

Entry nameiMEM12_ARATH
AccessioniPrimary (citable) accession number: Q9FK28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: March 1, 2001
Last modified: April 25, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health