Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Membrin-12

Gene

MEMB12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-ATH-5694530. Cargo concentration in the ER.
R-ATH-6807878. COPI-mediated anterograde transport.
R-ATH-6811438. Intra-Golgi traffic.

Names & Taxonomyi

Protein namesi
Recommended name:
Membrin-12
Short name:
AtMEMB12
Alternative name(s):
Golgi SNAP receptor complex member 2-2
Gene namesi
Name:MEMB12
Ordered Locus Names:At5g50440
ORF Names:MXI22.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G50440.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini2 – 197196CytoplasmicSequence analysisAdd
BLAST
Transmembranei198 – 21518Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini216 – 2194VesicularSequence analysis

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 219218Membrin-12PRO_0000212555Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Cross-linki107 – 107Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ9FK28.
PRIDEiQ9FK28.

PTM databases

iPTMnetiQ9FK28.

Expressioni

Gene expression databases

ExpressionAtlasiQ9FK28. baseline and differential.
GenevisibleiQ9FK28. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi20358. 24 interactions.
STRINGi3702.AT5G50440.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FK28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GOSR2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3251. Eukaryota.
ENOG4111M37. LUCA.
HOGENOMiHOG000264938.
InParanoidiQ9FK28.
KOiK08496.
OMAiRITSEME.
OrthoDBiEOG09360NTZ.
PhylomeDBiQ9FK28.

Family and domain databases

InterProiIPR027027. GOSR2/Membrin/Bos1.
[Graphical view]
PIRSFiPIRSF028865. Membrin-2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9FK28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGTVGGLS EVYSSAKRIL LRARNGIEKL ERFDSDPTDL ASSVKRDITE
60 70 80 90 100
VQSLCSNMDG LWRSIPVKSQ RDLWRRKSEQ VGEEAEYLNQ SLEKYMWRNQ
110 120 130 140 150
RKMLEAKERA DLLGRGSGEG AHILQIFDEE AQGMNSVKNS KRMLEDSFQS
160 170 180 190 200
GVAILSKYAE QRDRLKSAQR KALDVLNTVG LSNSVLRLIE RRNRVDTWIK
210
YAGMIATLVI LYLFIRWTR
Length:219
Mass (Da):25,105
Last modified:March 1, 2001 - v1
Checksum:i9885F002AF89B4EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012248 Genomic DNA. Translation: BAB09463.1.
CP002688 Genomic DNA. Translation: AED95946.1.
BT004999 mRNA. Translation: AAO50532.1.
RefSeqiNP_199855.1. NM_124426.4.
UniGeneiAt.29730.

Genome annotation databases

EnsemblPlantsiAT5G50440.1; AT5G50440.1; AT5G50440.
GeneIDi835112.
GrameneiAT5G50440.1; AT5G50440.1; AT5G50440.
KEGGiath:AT5G50440.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012248 Genomic DNA. Translation: BAB09463.1.
CP002688 Genomic DNA. Translation: AED95946.1.
BT004999 mRNA. Translation: AAO50532.1.
RefSeqiNP_199855.1. NM_124426.4.
UniGeneiAt.29730.

3D structure databases

ProteinModelPortaliQ9FK28.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi20358. 24 interactions.
STRINGi3702.AT5G50440.1.

PTM databases

iPTMnetiQ9FK28.

Proteomic databases

PaxDbiQ9FK28.
PRIDEiQ9FK28.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G50440.1; AT5G50440.1; AT5G50440.
GeneIDi835112.
GrameneiAT5G50440.1; AT5G50440.1; AT5G50440.
KEGGiath:AT5G50440.

Organism-specific databases

TAIRiAT5G50440.

Phylogenomic databases

eggNOGiKOG3251. Eukaryota.
ENOG4111M37. LUCA.
HOGENOMiHOG000264938.
InParanoidiQ9FK28.
KOiK08496.
OMAiRITSEME.
OrthoDBiEOG09360NTZ.
PhylomeDBiQ9FK28.

Enzyme and pathway databases

ReactomeiR-ATH-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-ATH-5694530. Cargo concentration in the ER.
R-ATH-6807878. COPI-mediated anterograde transport.
R-ATH-6811438. Intra-Golgi traffic.

Miscellaneous databases

PROiQ9FK28.

Gene expression databases

ExpressionAtlasiQ9FK28. baseline and differential.
GenevisibleiQ9FK28. AT.

Family and domain databases

InterProiIPR027027. GOSR2/Membrin/Bos1.
[Graphical view]
PIRSFiPIRSF028865. Membrin-2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMEM12_ARATH
AccessioniPrimary (citable) accession number: Q9FK28
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.