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Q9FJT8

- HATB_ARATH

UniProt

Q9FJT8 - HATB_ARATH

Protein

Histone acetyltransferase type B catalytic subunit

Gene

HAG2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Acetylates soluble but not nucleosomal H4 By similarity. Acetylates 'Lys-12' of histone H4.By similarity1 Publication

    Catalytic activityi

    Acetyl-CoA + [histone] = CoA + acetyl-[histone].

    GO - Molecular functioni

    1. H4 histone acetyltransferase activity Source: TAIR

    GO - Biological processi

    1. chromatin silencing at telomere Source: InterPro
    2. histone H4 acetylation Source: GOC

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciARA:AT5G56740-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone acetyltransferase type B catalytic subunit (EC:2.3.1.48)
    Short name:
    HAT B
    Gene namesi
    Name:HAG2
    Synonyms:HAT1
    Ordered Locus Names:At5g56740
    ORF Names:MIK19.19
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G56740.

    Subcellular locationi

    Nucleus By similarity. Cytoplasm By similarity

    GO - Cellular componenti

    1. cytosol Source: TAIR
    2. nucleus Source: TAIR

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 467467Histone acetyltransferase type B catalytic subunitPRO_0000232125Add
    BLAST

    Proteomic databases

    PaxDbiQ9FJT8.
    PRIDEiQ9FJT8.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9FJT8.

    Interactioni

    Protein-protein interaction databases

    BioGridi21019. 1 interaction.
    MINTiMINT-8062959.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FJT8.
    SMRiQ9FJT8. Positions 23-363.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the HAT1 family.Curated

    Phylogenomic databases

    eggNOGiNOG326277.
    HOGENOMiHOG000084749.
    InParanoidiQ9FJT8.
    KOiK11303.
    OMAiKEANFKP.
    PhylomeDBiQ9FJT8.

    Family and domain databases

    Gene3Di3.40.630.30. 1 hit.
    3.90.360.10. 2 hits.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR000182. GNAT_dom.
    IPR019467. Hat1_N.
    IPR017380. Hist_AcTrfase_B-typ_cat-su.
    [Graphical view]
    PANTHERiPTHR12046. PTHR12046. 1 hit.
    PfamiPF00583. Acetyltransf_1. 1 hit.
    PF10394. Hat1_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF038084. HAT-B_cat. 1 hit.
    SUPFAMiSSF55729. SSF55729. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9FJT8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVQKQQASAG PGTEPKKRRR VGFSPADTGV EANECIKIYL VSSKEEVDSS    50
    DISSVKPVDL NDFFDGDGKI YGYQGLKINV WINSISLHSY ADITYQSTIN 100
    GDKGITDLKS ALQNIFAETI VDTKDEFLQT FSTQRDFIRN MVSNGEVMHA 150
    GATDGSSKNA EVVPSDPQVI RMEIGSPNAG LLYSRLVPLV LLFVDGSNPI 200
    DVTDPDWHLY LLIQKKEEKE DPLYRIVGFT AIYKFYRYPD RLRMRLSQIL 250
    VLPSFQGKGL GSYLMEVVNN VAITENVYDL TVEEPSEKFQ HIRTCIDINR 300
    LRSFDPIKPD IDSAVQTLTK GKLSKKAQIP RFTPPLNAIE KVRESLKINK 350
    KQFLKCWEIL IYLALDPIDK YMEDYTSVIT NHVRTDILGK DIETPKKQVV 400
    DVPSSFEPEA SFVVFKSVNG EEANTNVQVD ENKPDQEQQL KQLVEERIRE 450
    IKLVAEKVSK SGQTLKV 467
    Length:467
    Mass (Da):52,738
    Last modified:March 1, 2001 - v1
    Checksum:i2B8A0465D6451662
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB013392 Genomic DNA. Translation: BAB09892.1.
    CP002688 Genomic DNA. Translation: AED96802.1.
    AF512724 mRNA. Translation: AAM70417.1.
    RefSeqiNP_200485.1. NM_125057.3.
    UniGeneiAt.27567.

    Genome annotation databases

    EnsemblPlantsiAT5G56740.1; AT5G56740.1; AT5G56740.
    GeneIDi835775.
    KEGGiath:AT5G56740.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB013392 Genomic DNA. Translation: BAB09892.1 .
    CP002688 Genomic DNA. Translation: AED96802.1 .
    AF512724 mRNA. Translation: AAM70417.1 .
    RefSeqi NP_200485.1. NM_125057.3.
    UniGenei At.27567.

    3D structure databases

    ProteinModelPortali Q9FJT8.
    SMRi Q9FJT8. Positions 23-363.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 21019. 1 interaction.
    MINTi MINT-8062959.

    Proteomic databases

    PaxDbi Q9FJT8.
    PRIDEi Q9FJT8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G56740.1 ; AT5G56740.1 ; AT5G56740 .
    GeneIDi 835775.
    KEGGi ath:AT5G56740.

    Organism-specific databases

    TAIRi AT5G56740.

    Phylogenomic databases

    eggNOGi NOG326277.
    HOGENOMi HOG000084749.
    InParanoidi Q9FJT8.
    KOi K11303.
    OMAi KEANFKP.
    PhylomeDBi Q9FJT8.

    Enzyme and pathway databases

    BioCyci ARA:AT5G56740-MONOMER.

    Miscellaneous databases

    PROi Q9FJT8.

    Gene expression databases

    Genevestigatori Q9FJT8.

    Family and domain databases

    Gene3Di 3.40.630.30. 1 hit.
    3.90.360.10. 2 hits.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR000182. GNAT_dom.
    IPR019467. Hat1_N.
    IPR017380. Hist_AcTrfase_B-typ_cat-su.
    [Graphical view ]
    PANTHERi PTHR12046. PTHR12046. 1 hit.
    Pfami PF00583. Acetyltransf_1. 1 hit.
    PF10394. Hat1_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF038084. HAT-B_cat. 1 hit.
    SUPFAMi SSF55729. SSF55729. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
      Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
      DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes."
      Pandey R., Mueller A., Napoli C.A., Selinger D.A., Pikaard C.S., Richards E.J., Bender J., Mount D.W., Jorgensen R.A.
      Nucleic Acids Res. 30:5036-5055(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 22-251, NOMENCLATURE.
    4. "Erasure of histone acetylation by Arabidopsis HDA6 mediates large-scale gene silencing in nucleolar dominance."
      Earley K., Lawrence R.J., Pontes O., Reuther R., Enciso A.J., Silva M., Neves N., Gross M., Viegas W., Pikaard C.S.
      Genes Dev. 20:1283-1293(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.

    Entry informationi

    Entry nameiHATB_ARATH
    AccessioniPrimary (citable) accession number: Q9FJT8
    Secondary accession number(s): Q8LKJ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3