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Q9FJ75 (WAXS4_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable long-chain-alcohol O-fatty-acyltransferase 4

EC=2.3.1.75
Alternative name(s):
Wax synthase 4
Gene names
Name:AT4
Ordered Locus Names:At5g55350
ORF Names:MTE17.6
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the final step in the synthesis of long-chain linear esters (waxes) By similarity.

Catalytic activity

Acyl-CoA + a long-chain alcohol = CoA + a long-chain ester.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the wax synthase family.

Ontologies

Keywords
   Biological processLipid biosynthesis
Lipid metabolism
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlipid metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionlong-chain-alcohol O-fatty-acyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 345345Probable long-chain-alcohol O-fatty-acyltransferase 4
PRO_0000380680

Regions

Transmembrane5 – 2521Helical; Potential
Transmembrane36 – 5621Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane143 – 16321Helical; Potential
Transmembrane226 – 24621Helical; Potential
Transmembrane254 – 27421Helical; Potential
Transmembrane288 – 30821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9FJ75 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: F945759348905BFB

FASTA34539,825
        10         20         30         40         50         60 
MEEELMSLIK VWVYAIISIS YCYYTSTRIK SGVFRLLSVL PVCVLFLVLP LFVSSVHFSG 

        70         80         90        100        110        120 
STAFFLSWLA NFKLILFSFD QGPLFPVPSN LSRFVCFTCF PIKLQQNPKP QNQMPKWGFA 

       130        140        150        160        170        180 
VKLAFFGVLL HMYEYKQHMS PTVLLVLYSL HIYLEYEILL APLKVLLSIS LWCDLEPHFN 

       190        200        210        220        230        240 
EPYLSTSLQD FWGRRWNLMV PAILRPAVYL PVRQMAGRKM NSDQALFLGV FASFLVSGVV 

       250        260        270        280        290        300 
HELIFFYFTR ESPTGEVTLF FVLHGVCTAA ECAAKRTRLV RRWKVSQMVS RLLTVGFVVM 

       310        320        330        340 
TGGWLFFPHL ARSGMIERLA DEAFLFIGFV KHKFFYLCRN QSLKS 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence features of the regions of 1,013,767 bp covered by sixteen physically assigned P1 and TAC clones."
Nakamura Y., Sato S., Asamizu E., Kaneko T., Kotani H., Miyajima N., Tabata S.
DNA Res. 5:297-308(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D.
Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Purification of a jojoba embryo wax synthase, cloning of its cDNA, and production of high levels of wax in seeds of transgenic arabidopsis."
Lardizabal K.D., Metz J.G., Sakamoto T., Hutton W.C., Pollard M.R., Lassner M.W.
Plant Physiol. 122:645-655(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB015479 Genomic DNA. Translation: BAB08552.1.
CP002688 Genomic DNA. Translation: AED96619.1.
DQ056722 mRNA. Translation: AAY78866.1.
RefSeqNP_200346.1. NM_124917.1.
UniGeneAt.62440.

3D structure databases

ProteinModelPortalQ9FJ75.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G55350.1-P.

Proteomic databases

PaxDbQ9FJ75.
PRIDEQ9FJ75.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G55350.1; AT5G55350.1; AT5G55350.
GeneID835628.
KEGGath:AT5G55350.

Organism-specific databases

TAIRAT5G55350.

Phylogenomic databases

eggNOGNOG284813.
HOGENOMHOG000238128.
InParanoidQ9FJ75.
OMAYLEYEIL.
PhylomeDBQ9FJ75.
ProtClustDBCLSN2679624.

Enzyme and pathway databases

BioCycARA:AT5G55350-MONOMER.

Gene expression databases

GenevestigatorQ9FJ75.

Family and domain databases

InterProIPR017088. Wax_synthase.
[Graphical view]
PIRSFPIRSF037006. Wax_synthase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameWAXS4_ARATH
AccessionPrimary (citable) accession number: Q9FJ75
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 1, 2001
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names