Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9FIK0 (K6PF2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phosphofructokinase 2

EC=2.7.1.11
Alternative name(s):
Phosphofructokinase 2
Phosphohexokinase 2
Gene names
Name:PFK2
Ordered Locus Names:At5g47810
ORF Names:MCA23.13
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. Ref.4

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.

Subcellular location

Cytoplasm Ref.4.

Tissue specificity

Mostly expressed in roots and stems. Ref.4

Sequence similarities

Belongs to the phosphofructokinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4444446-phosphofructokinase 2
PRO_0000330769

Regions

Nucleotide binding96 – 1005ATP By similarity
Nucleotide binding232 – 2365ATP By similarity
Nucleotide binding250 – 26718ATP By similarity

Sites

Active site2051Proton acceptor By similarity

Amino acid modifications

Modified residue551Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9FIK0 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 42E78785792A73EC

FASTA44449,182
        10         20         30         40         50         60 
MAAETSIRKL PSLSGLRHRR NPLEDNPYFH PSNGFYITPS DVILAQVAYD HSAHSQSRVA 

        70         80         90        100        110        120 
YHRAGPRREI MYEPSAVKAA IVTCGGLCPG MNTVIRELVV GLWELYGVRE IYGIPAGYRG 

       130        140        150        160        170        180 
FYSMKAVKLD PKAVHDWHKK GGTVLATSRG GFHLQKIVDA IHLNGYNQVY IIGGDGTMRG 

       190        200        210        220        230        240 
AVEIFKEISL RKLEVGITVI PKTVDNDVGI IDRSFGFQTA VEMAQEAISA AHVEAESAVN 

       250        260        270        280        290        300 
GIGLVKLMGR STGHIALHAT LSSRDVDCCL IPEMDFYLEG KGGLFEFLEK RLKERGHAVL 

       310        320        330        340        350        360 
VVAEGAGQEM IPRNESQKQE RDESGNAVFL DVGVWFKSVL KAWWEREHPD ELFTVKYIDP 

       370        380        390        400        410        420 
TYMIRAVPAN ATDNLYCTLL AHSAIHGVMA GYTGFVPGPI NGNYAYIPLE EVAQTKNQVN 

       430        440 
TRDHKWAWVR SVTNQPDFET NVKG 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones."
Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N., Tabata S.
DNA Res. 5:379-391(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Characterisation of the ATP-dependent phosphofructokinase gene family from Arabidopsis thaliana."
Mustroph A., Sonnewald U., Biemelt S.
FEBS Lett. 581:2401-2410(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: CATALYTIC ACTIVITY, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB016886 Genomic DNA. Translation: BAB11328.1.
CP002688 Genomic DNA. Translation: AED95574.1.
AY056779 mRNA. Translation: AAL09725.1.
AY090379 mRNA. Translation: AAL91281.1.
RefSeqNP_199592.1. NM_124155.2.
UniGeneAt.9400.

3D structure databases

ProteinModelPortalQ9FIK0.
SMRQ9FIK0. Positions 9-433.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid20080. 1 interaction.
IntActQ9FIK0. 7 interactions.
STRING3702.AT5G47810.1-P.

Proteomic databases

PaxDbQ9FIK0.
PRIDEQ9FIK0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G47810.1; AT5G47810.1; AT5G47810.
GeneID834832.
KEGGath:AT5G47810.

Organism-specific databases

TAIRAT5G47810.

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000016186.
InParanoidQ9FIK0.
KOK00850.
OMASELKNWW.
PhylomeDBQ9FIK0.

Enzyme and pathway databases

BioCycARA:AT5G47810-MONOMER.
UniPathwayUPA00109; UER00182.

Gene expression databases

GenevestigatorQ9FIK0.

Family and domain databases

InterProIPR022953. Phosphofructokinase.
IPR000023. Phosphofructokinase_dom.
IPR012004. PyroP-dep_PFruKinase_TP0108.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000534. PPi_PFK_TP0108. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
ProtoNetSearch...

Entry information

Entry nameK6PF2_ARATH
AccessionPrimary (citable) accession number: Q9FIK0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: March 1, 2001
Last modified: April 16, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names