Q9FIJ7 (KADC2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable adenylate kinase 2, chloroplastic
Short name=AK 2
EC=2.7.4.3

Alternative name(s):
ATP-AMP transphosphorylase 2

Gene names

Ordered Locus Names:	At5g47840
ORF Names:	MCA23.18

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	This small ubiquitous enzyme is essential for maintenance and cell growth By similarity.
Catalytic activity	ATP + AMP = 2 ADP.
Subcellular location	Plastid › chloroplast By similarity.
Sequence similarities	Belongs to the adenylate kinase family.

Ontologies

Keywords
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	chloroplast stroma Inferred from direct assay PubMed 16207701PubMed 18633119PubMed 20061580. Source: TAIR
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW adenylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 59	59	Chloroplast Potential
	Chain	60 – 283	224	Probable adenylate kinase 2, chloroplastic		PRO_0000016555
Regions
	Nucleotide binding	71 – 79	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9FIJ7 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 1461D1A36F2DF4E9	FASTA	283	31,452
	10 20 30 40 50 60 MTGCVNSISP PPVTLYRHRA SPSRSSFSLS GDALHSLYRH RRVSRSPSII APKFQIVAAE 70 80 90 100 110 120 KSEPLKIMIS GAPASGKGTQ CELITHKYGL VHISAGDLLR AEIASGSENG RRAKEHMEKG 130 140 150 160 170 180 QLVPDEIVVM MVKDRLSQTD SEQKGWLLDG YPRSASQATA LKGFGFQPDL FIVLEVPEEI 190 200 210 220 230 240 LIERVVGRRL DPVTGKIYHL KYSPPETEEI AVRLTQRFDD TEEKAKLRLK THNQNVSDVL 250 260 270 280 SMYDDITIKI EGNRSKEEVF AQIDSSLSEL LQERNTAPSS LLS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones." Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N., Tabata S. DNA Res. 5:379-391(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB016886 Genomic DNA. Translation: BAB11331.1. CP002688 Genomic DNA. Translation: AED95579.1. AY049305 mRNA. Translation: AAK83647.1. BT001036 mRNA. Translation: AAN46790.1.
IPI	IPI00535372.
RefSeq	NP_199595.1. NM_124158.3.
UniGene	At.22595.
3D structure databases
ProteinModelPortal	Q9FIJ7.
SMR	Q9FIJ7. Positions 62-280.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT5G47840.1-P.
Proteomic databases
PaxDb	Q9FIJ7.
PRIDE	Q9FIJ7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G47840.1; AT5G47840.1; AT5G47840.
GeneID	834835.
KEGG	ath:AT5G47840.
Organism-specific databases
TAIR	At5g47840.
Phylogenomic databases
eggNOG	COG0563.
HOGENOM	HOG000238772.
InParanoid	Q9FIJ7.
KO	K00939.
OMA	VMMVKDR.
PhylomeDB	Q9FIJ7.
ProtClustDB	CLSN2916325.
Gene expression databases
Genevestigator	Q9FIJ7.
GermOnline	AT5G47840. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR006259. Adenyl_kin_sub. IPR000850. Adenylate_kin. [Graphical view]
PANTHER	PTHR23359. PTHR23359. 1 hit.
Pfam	PF00406. ADK. 1 hit. [Graphical view]
PRINTS	PR00094. ADENYLTKNASE.
TIGRFAMs	TIGR01351. adk. 1 hit.
PROSITE	PS00113. ADENYLATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KADC2_ARATH

Accession

Primary (citable) accession number: Q9FIJ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program