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Q9FIF5

- P2C78_ARATH

UniProt

Q9FIF5 - P2C78_ARATH

Protein

Probable protein phosphatase 2C 78

Gene

At5g59220

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi153 – 1531Manganese 1By similarity
    Metal bindingi153 – 1531Manganese 2By similarity
    Metal bindingi154 – 1541Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi327 – 3271Manganese 2By similarity
    Metal bindingi400 – 4001Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: TAIR

    GO - Biological processi

    1. chloroplast organization Source: TAIR
    2. dephosphorylation Source: GOC
    3. leaf senescence Source: TAIR
    4. negative regulation of abscisic acid-activated signaling pathway Source: TAIR
    5. response to abscisic acid Source: TAIR
    6. response to water deprivation Source: TAIR
    7. stomatal movement Source: TAIR

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G59220-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 78 (EC:3.1.3.16)
    Short name:
    AtPP2C78
    Gene namesi
    Ordered Locus Names:At5g59220
    ORF Names:MNC17.110
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G59220.

    Subcellular locationi

    GO - Cellular componenti

    1. cis-Golgi network membrane Source: TAIR
    2. cytosol Source: TAIR
    3. Golgi apparatus Source: TAIR
    4. nucleus Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 413413Probable protein phosphatase 2C 78PRO_0000367997Add
    BLAST

    Proteomic databases

    PRIDEiQ9FIF5.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9FIF5.

    Interactioni

    Protein-protein interaction databases

    BioGridi21284. 34 interactions.
    DIPiDIP-48992N.
    IntActiQ9FIF5. 2 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FIF5.
    SMRiQ9FIF5. Positions 110-410.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini110 – 402293PP2C-likeAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi66 – 705Poly-Arg

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ9FIF5.
    KOiK14497.
    OMAiCYENETM.
    PhylomeDBiQ9FIF5.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q9FIF5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEICYENET MMIETTATVV KKATTTTRRR ERSSSQAARR RRMEIRRFKF    50
    VSGEQEPVFV DGDLQRRRRR ESTVAASTST VFYETAKEVV VLCESLSSTV 100
    VALPDPEAYP KYGVASVCGR RREMEDAVAV HPFFSRHQTE YSSTGFHYCG 150
    VYDGHGCSHV AMKCRERLHE LVREEFEADA DWEKSMARSF TRMDMEVVAL 200
    NADGAAKCRC ELQRPDCDAV GSTAVVSVLT PEKIIVANCG DSRAVLCRNG 250
    KAIALSSDHK PDRPDELDRI QAAGGRVIYW DGPRVLGVLA MSRAIGDNYL 300
    KPYVISRPEV TVTDRANGDD FLILASDGLW DVVSNETACS VVRMCLRGKV 350
    NGQVSSSPER EMTGVGAGNV VVGGGDLPDK ACEEASLLLT RLALARQSSD 400
    NVSVVVVDLR RDT 413
    Length:413
    Mass (Da):45,538
    Last modified:March 1, 2001 - v1
    Checksum:i649CF986D17A92D7
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti103 – 1031L → F in AAL16163. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB016890 Genomic DNA. Translation: BAB09767.1.
    CP002688 Genomic DNA. Translation: AED97159.1.
    AF428395 mRNA. Translation: AAL16163.1.
    AY054163 mRNA. Translation: AAL06824.1.
    AY074555 mRNA. Translation: AAL67095.1.
    RefSeqiNP_200730.1. NM_125312.2.
    UniGeneiAt.22149.

    Genome annotation databases

    EnsemblPlantsiAT5G59220.1; AT5G59220.1; AT5G59220.
    GeneIDi836040.
    KEGGiath:AT5G59220.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB016890 Genomic DNA. Translation: BAB09767.1 .
    CP002688 Genomic DNA. Translation: AED97159.1 .
    AF428395 mRNA. Translation: AAL16163.1 .
    AY054163 mRNA. Translation: AAL06824.1 .
    AY074555 mRNA. Translation: AAL67095.1 .
    RefSeqi NP_200730.1. NM_125312.2.
    UniGenei At.22149.

    3D structure databases

    ProteinModelPortali Q9FIF5.
    SMRi Q9FIF5. Positions 110-410.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 21284. 34 interactions.
    DIPi DIP-48992N.
    IntActi Q9FIF5. 2 interactions.

    Proteomic databases

    PRIDEi Q9FIF5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G59220.1 ; AT5G59220.1 ; AT5G59220 .
    GeneIDi 836040.
    KEGGi ath:AT5G59220.

    Organism-specific databases

    TAIRi AT5G59220.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q9FIF5.
    KOi K14497.
    OMAi CYENETM.
    PhylomeDBi Q9FIF5.

    Enzyme and pathway databases

    BioCyci ARA:AT5G59220-MONOMER.

    Gene expression databases

    Genevestigatori Q9FIF5.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones."
      Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N., Tabata S.
      DNA Res. 5:379-391(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C78_ARATH
    AccessioniPrimary (citable) accession number: Q9FIF5
    Secondary accession number(s): Q944I7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3