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Protein

Protein MITOFERRINLIKE 1, chloroplastic

Gene

MFL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Probably involved in iron transport into chloroplasts.1 Publication

GO - Molecular functioni

GO - Biological processi

  • iron ion transport Source: TAIR
  • mitochondrial transport Source: GO_Central
  • response to iron ion Source: TAIR

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MITOFERRINLIKE 1, chloroplastic
Short name:
AtMFL1
Gene namesi
Name:MFL1
Ordered Locus Names:At5g42130
ORF Names:MJC20.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G42130.
TAIRilocus:2165755. AT5G42130.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei115 – 135Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei167 – 187Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei208 – 228Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei262 – 282Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei303 – 323Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei365 – 385Helical; Name=6Sequence analysisAdd BLAST21

GO - Cellular componenti

  • chloroplast Source: TAIR
  • chloroplast envelope Source: TAIR
  • chloroplast inner membrane Source: UniProtKB-SubCell
  • integral component of membrane Source: GO_Central
  • mitochondrial inner membrane Source: GO_Central
  • plastid Source: TAIR

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Plastid inner membrane

Pathology & Biotechi

Disruption phenotypei

Reduced vegetative growth and reduced expression of ferritin.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 92ChloroplastSequence analysisAdd BLAST92
ChainiPRO_000041320893 – 412Protein MITOFERRINLIKE 1, chloroplasticAdd BLAST320

Proteomic databases

PaxDbiQ9FHX2.
PRIDEiQ9FHX2.

Expressioni

Tissue specificityi

Expressed in leaves, developing flowers and siliques.1 Publication

Inductioni

Up-regulated by iron excess.1 Publication

Gene expression databases

ExpressionAtlasiQ9FHX2. baseline and differential.
GenevisibleiQ9FHX2. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G42130.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FHX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati112 – 198Solcar 1Add BLAST87
Repeati206 – 288Solcar 2Add BLAST83
Repeati298 – 392Solcar 3Add BLAST95

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0768. Eukaryota.
ENOG4110BII. LUCA.
HOGENOMiHOG000038810.
InParanoidiQ9FHX2.
OMAiYQGIGSV.
OrthoDBiEOG09360CAZ.
PhylomeDBiQ9FHX2.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9FHX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEARLSETLG LPSPNLNHCH FPNEFNSLFT HFSDLTSVQS PIVRNPKLKT
60 70 80 90 100
KSSQKPPKFS ANFRRSDPPF ASTSISDPTH EKPGPEFLKW IKPASRSSPR
110 120 130 140 150
IQTLIKQLSV WERAIIGAGA GGLAGAFTYV TLLPLDAIKT KLQTKGASQV
160 170 180 190 200
YSNTFDAIVK TFQAKGILGF YSGVSAVIVG STFSSAVYFG TCEFGKSLLS
210 220 230 240 250
KFPDFPTVLI PPTAGAMGNI ISSAIMVPKE LITQRMQAGA SGRSYQVLLK
260 270 280 290 300
ILEKDGILGL YAGYSATLLR NLPAGVLSYS SFEYLKAAVL EKTKQSHLEP
310 320 330 340 350
LQSVCCGALA GAISASITTP LDVVKTRLMT QIHVEAVDKL GGAMYTGVAG
360 370 380 390 400
TVKQILTEEG WVGFTRGMGP RVVHSACFSA IGYFAFETAR LTILNEYLKR
410
KEESEANVAA DS
Length:412
Mass (Da):44,361
Last modified:March 1, 2001 - v1
Checksum:iE23FD31848EB51D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017067 Genomic DNA. Translation: BAB08446.1.
CP002688 Genomic DNA. Translation: AED94771.1.
RefSeqiNP_199028.1. NM_123578.4.
UniGeneiAt.30188.

Genome annotation databases

EnsemblPlantsiAT5G42130.1; AT5G42130.1; AT5G42130.
GeneIDi834218.
GrameneiAT5G42130.1; AT5G42130.1; AT5G42130.
KEGGiath:AT5G42130.

Similar proteinsi

Entry informationi

Entry nameiMFL1_ARATH
AccessioniPrimary (citable) accession number: Q9FHX2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: March 1, 2001
Last modified: June 7, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families