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Q9FHE1 (GSTT3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase T3

Short name=AtGSTT3
EC=2.5.1.18
Alternative name(s):
GST class-theta member 3
Glutathione S-transferase 10C
Gene names
Name:GSTT3
Synonyms:GST10C
Ordered Locus Names:At5g41220
ORF Names:K1O13.1
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length590 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subcellular location

Nucleus Ref.4.

Sequence similarities

Belongs to the GST superfamily. Theta family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Contains 1 Myb-like domain.

Ontologies

Keywords
   Biological processDetoxification
   Cellular componentNucleus
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to toxic substance

Inferred from electronic annotation. Source: UniProtKB-KW

toxin catabolic process

Traceable author statement Ref.5. Source: TAIR

   Cellular_componentcytoplasm

Non-traceable author statement Ref.5. Source: TAIR

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

glutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 590590Glutathione S-transferase T3
PRO_0000413576

Regions

Domain1 – 8282GST N-terminal
Domain89 – 232144GST C-terminal
Domain265 – 33672Myb-like
Region11 – 122Glutathione binding By similarity
Region40 – 412Glutathione binding By similarity
Region53 – 542Glutathione binding By similarity
Region66 – 672Glutathione binding By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9FHE1 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: E85F66525F6C7AF5

FASTA59067,555
        10         20         30         40         50         60 
MKLKVYADRM SQPSRAVLIF CKVNEIQFDE ILIYLANRQQ LSPEFKDINP MGKVPAIVDG 

        70         80         90        100        110        120 
KLKLSESHAI LIYLSSAYPS VVDHWYPTDL SKRARIHSVL DWHHTNLRPG AAGYVLNSVL 

       130        140        150        160        170        180 
GPALGLPLNP KAAAEAEQLL TKSLTTLDTF WLKGNAMFLL GSNQPSIADL SLVCELTQLQ 

       190        200        210        220        230        240 
VLDDKDRLRL LSPHKNVEQW IENTRKATMP HFDEVHEVLF RAKDRCQKQR EMATASKPGP 

       250        260        270        280        290        300 
QSKIIQFSTI GEKSDDPNLV QNTTDRRKHR RKWSRAEDAI LISAWLNTSK DPIVDNEHKA 

       310        320        330        340        350        360 
CAFWKRIGAY FNNSASLANL PKREPSHCKQ RWSKLNDKVC KFVGCYDQAL NQRSSGQSED 

       370        380        390        400        410        420 
DVFQVAYQVY TNNYKSNFTL EHAWRELRHS KKWCSLYPFE NSKGGGSSKR TKLNNGDRVY 

       430        440        450        460        470        480 
SSSSNPESVP IALDEEEQVM DLPLGVKSSK QKEKKVATII TIEEREADSG SRLENLWVLD 

       490        500        510        520        530        540 
EEEQVMDRPL GVKSLEQKEN KVAPKPTIEE REAADSRSRL ENLWALKEKE EREADSRSRL 

       550        560        570        580        590 
ENLWALKEKD IEEQKKLTRM EVLKSLLGRT TDQLSEKEDI LKNKLIDEML 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S.
DNA Res. 7:31-63(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 249-590.
Strain: cv. Columbia.
[4]"Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily."
Dixon D.P., Hawkins T., Hussey P.J., Edwards R.
J. Exp. Bot. 60:1207-1218(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
[5]"Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
Wagner U., Edwards R., Dixon D.P., Mauch F.
Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB019225 Genomic DNA. Translation: BAB11098.1.
CP002688 Genomic DNA. Translation: AED94655.1.
AK222098 mRNA. Translation: BAD95009.1.
RefSeqNP_198938.1. NM_123487.3.
UniGeneAt.30245.

3D structure databases

ProteinModelPortalQ9FHE1.
SMRQ9FHE1. Positions 1-249.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G41220.1-P.

Proteomic databases

PRIDEQ9FHE1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G41220.1; AT5G41220.1; AT5G41220.
GeneID834124.
KEGGath:AT5G41220.

Organism-specific databases

TAIRAT5G41220.

Phylogenomic databases

eggNOGCOG0625.
HOGENOMHOG000148624.
InParanoidQ9FHE1.
PhylomeDBQ9FHE1.
ProtClustDBCLSN2686230.

Enzyme and pathway databases

BioCycARA:AT5G41220-MONOMER.

Gene expression databases

GenevestigatorQ9FHE1.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR009057. Homeodomain-like.
IPR017877. Myb-like_dom.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
PS50090. MYB_LIKE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTT3_ARATH
AccessionPrimary (citable) accession number: Q9FHE1
Secondary accession number(s): Q56WE4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: March 1, 2001
Last modified: March 19, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names