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Protein

Beta-glucosidase 12

Gene

BGLU12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei50SubstrateBy similarity1
Binding sitei154SubstrateBy similarity1
Binding sitei199SubstrateBy similarity1
Active sitei200Proton donorBy similarity1
Binding sitei344SubstrateBy similarity1
Active sitei414NucleophileBy similarity1
Binding sitei459SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Enzyme and pathway databases

BioCyciARA:AT5G42260-MONOMER
ReactomeiR-ATH-189085 Digestion of dietary carbohydrate

Protein family/group databases

CAZyiGH1 Glycoside Hydrolase Family 1

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase 12 (EC:3.2.1.21)
Short name:
AtBGLU12
Gene namesi
Name:BGLU12
Ordered Locus Names:At5g42260
ORF Names:K5J14.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G42260
TAIRilocus:2157632 AT5G42260

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000038957523 – 507Beta-glucosidase 12Add BLAST485

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi81N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi219 ↔ 227By similarity
Glycosylationi226N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi358N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9FH03
PRIDEiQ9FH03

Expressioni

Gene expression databases

ExpressionAtlasiQ9FH03 baseline
GenevisibleiQ9FH03 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G42260.1

Structurei

3D structure databases

ProteinModelPortaliQ9FH03
SMRiQ9FH03
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni466 – 467Substrate bindingBy similarity2

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG0626 Eukaryota
COG2723 LUCA
HOGENOMiHOG000088630
KOiK01188
OMAiIVYITEC
OrthoDBiEOG093606W7
PhylomeDBiQ9FH03

Family and domain databases

InterProiView protein in InterPro
IPR001360 Glyco_hydro_1
IPR033132 Glyco_hydro_1_N_CS
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR10353 PTHR10353, 1 hit
PfamiView protein in Pfam
PF00232 Glyco_hydro_1, 1 hit
PRINTSiPR00131 GLHYDRLASE1
SUPFAMiSSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS00653 GLYCOSYL_HYDROL_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9FH03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTIYLSLLV FIIVLALNEV MAKKHSSTPK LRRSDFPEDF IFGAATSAYQ
60 70 80 90 100
VEGAAHEDGR GPSIWDTFSE KYPEKIKDGS NGSIASDSYH LYKEDVGLLH
110 120 130 140 150
QIGFDAYRFS ISWSRILPRE NLKGGINQAG IDYYNNLINE LLSKGIKPFA
160 170 180 190 200
TIFHWDTPQS LEDAYGGFLG AEIVNDFRDY ADICFKNFGD RVKHWMTLNE
210 220 230 240 250
PLTVVQQGYV AGVMAPGRCS KFTNPNCTAG NGATEPYIVG HNLILAHGEA
260 270 280 290 300
VKVYREKYKA SQKGQVGIAL NAGWNLPYSE SAEDRLAAAR AMAFTFDYFM
310 320 330 340 350
EPLVTGKYPI DMVNYVKGGR LPTFTAKQSK MLKGSYDFIG RNYYSSSYAK
360 370 380 390 400
DVPCSSENVT LFSDPCASVT GEREGVPIGP KAASDWLLIY PKGIRDLLLY
410 420 430 440 450
AKYKFKDPVM YITENGRDEA STGKIDLKDS ERIDYYAQHL KMVQDAISIG
460 470 480 490 500
ANVKGFFAWS LLDNFEWATG YAVRFGLVYV DFNGGRKRYP KKSAKWFKKL

LNEKKKN
Length:507
Mass (Da):56,966
Last modified:March 1, 2001 - v1
Checksum:i7F7197A3D50D45C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023032 Genomic DNA Translation: BAB10199.1
CP002688 Genomic DNA Translation: AED94789.1
DQ056704 mRNA Translation: AAY78850.1
RefSeqiNP_199041.1, NM_123591.2
UniGeneiAt.55316

Genome annotation databases

EnsemblPlantsiAT5G42260.1; AT5G42260.1; AT5G42260
GeneIDi834231
GrameneiAT5G42260.1; AT5G42260.1; AT5G42260
KEGGiath:AT5G42260

Similar proteinsi

Entry informationi

Entry nameiBGL12_ARATH
AccessioniPrimary (citable) accession number: Q9FH03
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: March 1, 2001
Last modified: April 25, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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