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Protein

Beta-glucosidase 12

Gene

BGLU12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei50SubstrateBy similarity1
Binding sitei154SubstrateBy similarity1
Binding sitei199SubstrateBy similarity1
Active sitei200Proton donorBy similarity1
Binding sitei344SubstrateBy similarity1
Active sitei414NucleophileBy similarity1
Binding sitei459SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciARA:AT5G42260-MONOMER.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase 12 (EC:3.2.1.21)
Short name:
AtBGLU12
Gene namesi
Name:BGLU12
Ordered Locus Names:At5g42260
ORF Names:K5J14.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G42260.

Subcellular locationi

GO - Cellular componenti

  • Golgi apparatus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000038957523 – 507Beta-glucosidase 12Add BLAST485

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi81N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi219 ↔ 227By similarity
Glycosylationi226N-linked (GlcNAc...)Sequence analysis1
Glycosylationi358N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9FH03.
PRIDEiQ9FH03.

Expressioni

Gene expression databases

GenevisibleiQ9FH03. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G42260.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FH03.
SMRiQ9FH03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni466 – 467Substrate bindingBy similarity2

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG0626. Eukaryota.
COG2723. LUCA.
HOGENOMiHOG000088630.
KOiK01188.
OMAiACNEAIA.
OrthoDBiEOG093606W7.
PhylomeDBiQ9FH03.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR033132. Glyco_hydro_1_N_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9FH03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTIYLSLLV FIIVLALNEV MAKKHSSTPK LRRSDFPEDF IFGAATSAYQ
60 70 80 90 100
VEGAAHEDGR GPSIWDTFSE KYPEKIKDGS NGSIASDSYH LYKEDVGLLH
110 120 130 140 150
QIGFDAYRFS ISWSRILPRE NLKGGINQAG IDYYNNLINE LLSKGIKPFA
160 170 180 190 200
TIFHWDTPQS LEDAYGGFLG AEIVNDFRDY ADICFKNFGD RVKHWMTLNE
210 220 230 240 250
PLTVVQQGYV AGVMAPGRCS KFTNPNCTAG NGATEPYIVG HNLILAHGEA
260 270 280 290 300
VKVYREKYKA SQKGQVGIAL NAGWNLPYSE SAEDRLAAAR AMAFTFDYFM
310 320 330 340 350
EPLVTGKYPI DMVNYVKGGR LPTFTAKQSK MLKGSYDFIG RNYYSSSYAK
360 370 380 390 400
DVPCSSENVT LFSDPCASVT GEREGVPIGP KAASDWLLIY PKGIRDLLLY
410 420 430 440 450
AKYKFKDPVM YITENGRDEA STGKIDLKDS ERIDYYAQHL KMVQDAISIG
460 470 480 490 500
ANVKGFFAWS LLDNFEWATG YAVRFGLVYV DFNGGRKRYP KKSAKWFKKL

LNEKKKN
Length:507
Mass (Da):56,966
Last modified:March 1, 2001 - v1
Checksum:i7F7197A3D50D45C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023032 Genomic DNA. Translation: BAB10199.1.
CP002688 Genomic DNA. Translation: AED94789.1.
DQ056704 mRNA. Translation: AAY78850.1.
RefSeqiNP_199041.1. NM_123591.2.
UniGeneiAt.55316.

Genome annotation databases

EnsemblPlantsiAT5G42260.1; AT5G42260.1; AT5G42260.
GeneIDi834231.
GrameneiAT5G42260.1; AT5G42260.1; AT5G42260.
KEGGiath:AT5G42260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB023032 Genomic DNA. Translation: BAB10199.1.
CP002688 Genomic DNA. Translation: AED94789.1.
DQ056704 mRNA. Translation: AAY78850.1.
RefSeqiNP_199041.1. NM_123591.2.
UniGeneiAt.55316.

3D structure databases

ProteinModelPortaliQ9FH03.
SMRiQ9FH03.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G42260.1.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Proteomic databases

PaxDbiQ9FH03.
PRIDEiQ9FH03.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G42260.1; AT5G42260.1; AT5G42260.
GeneIDi834231.
GrameneiAT5G42260.1; AT5G42260.1; AT5G42260.
KEGGiath:AT5G42260.

Organism-specific databases

TAIRiAT5G42260.

Phylogenomic databases

eggNOGiKOG0626. Eukaryota.
COG2723. LUCA.
HOGENOMiHOG000088630.
KOiK01188.
OMAiACNEAIA.
OrthoDBiEOG093606W7.
PhylomeDBiQ9FH03.

Enzyme and pathway databases

BioCyciARA:AT5G42260-MONOMER.

Miscellaneous databases

PROiQ9FH03.

Gene expression databases

GenevisibleiQ9FH03. AT.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR033132. Glyco_hydro_1_N_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBGL12_ARATH
AccessioniPrimary (citable) accession number: Q9FH03
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: March 1, 2001
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.