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Q9FGX2 (BZIP1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Basic leucine zipper 1

Short name=AtbZIP1
Short name=bZIP protein 1
Gene names
Name:BZIP1
Ordered Locus Names:At5g49450
ORF Names:K7J8.13
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transcription factor that binds to the C-box-like motif (5'-TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters involved in sugar signaling. Activated by low energy stress both at transcriptional and post-transcriptional mechanisms. Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark-induced starvation response. Ref.9 Ref.10

Subunit structure

Interacts with ZFP7, BZIP4, BZIP9, BZIP10, BZIP11, BZIP25, BZIP42, BZIP44, BZIP53, BZIP58 and BZIP63. Ref.7 Ref.9 Ref.10

Subcellular location

Nucleus By similarity.

Tissue specificity

Expressed in both shoots, including young leaves, stipulae and trichomes (except in cotyledons and hypocotyl), and roots, including vascular tissues (e.g. in both the phloem and the xylem). Present in seeds and pollen. Restricted to vasculatures and roots in the presence of sucrose or glucose. Ref.8 Ref.9

Developmental stage

Expressed in seeds during late stage of development. Ref.8

Induction

Reversibly repressed by glucose and mannose. Slowly induced by Pseudomonas syringae. Induced in roots upon cold and salt stress but then repressed in leaves. Promoted by low energy stress and dark-induced starvation. Ref.8 Ref.9 Ref.10

Disruption phenotype

Reduced requirement for exogenous sugar for seedling growth and higher rates of true leaf development. Ref.9

Sequence similarities

Belongs to the bZIP family.

Contains 1 bZIP (basic-leucine zipper) domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   LigandDNA-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processanther dehiscence

Inferred from mutant phenotype PubMed 18502975. Source: TAIR

cellular response to glucose stimulus

Inferred from expression pattern Ref.8. Source: UniProtKB

cellular response to starvation

Inferred from expression pattern Ref.10. Source: UniProtKB

positive regulation of transcription, DNA-templated

Inferred from direct assay PubMed 21938515. Source: TAIR

regulation of cellular amino acid metabolic process

Inferred from mutant phenotype Ref.10. Source: UniProtKB

response to bacterium

Inferred from expression pattern Ref.8. Source: UniProtKB

response to osmotic stress

Inferred from mutant phenotype PubMed 21938515. Source: TAIR

response to salt stress

Inferred from mutant phenotype PubMed 21938515. Source: TAIR

sugar mediated signaling pathway

Inferred from mutant phenotype Ref.9. Source: UniProtKB

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from direct assay PubMed 21938515. Source: TAIR

   Molecular_functionprotein binding

Inferred from physical interaction Ref.10. Source: UniProtKB

protein heterodimerization activity

Inferred from physical interaction Ref.7Ref.9. Source: UniProtKB

sequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from direct assay Ref.9. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145Basic leucine zipper 1
PRO_0000416557

Regions

Domain14 – 7764bZIP
Region16 – 3722Basic motif By similarity
Region46 – 538Leucine-zipper By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9FGX2 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 5137A1CCE8638C0A

FASTA14516,224
        10         20         30         40         50         60 
MANAEKTSSG SDIDEKKRKR KLSNRESARR SRLKKQKLME DTIHEISSLE RRIKENSERC 

        70         80         90        100        110        120 
RAVKQRLDSV ETENAGLRSE KIWLSSYVSD LENMIATTSL TLTQSGGGDC VDDQNANAGI 

       130        140 
AVGDCRRTPW KLSCGSLQPM ASFKT 

« Hide

References

« Hide 'large scale' references
[1]"AtbZIP1, a transcription factor in Arabidopsis thaliana."
Wang X., Droege-Laser W.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S.
DNA Res. 7:31-63(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[6]"bZIP transcription factors in Arabidopsis."
Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J., Tiedemann J., Kroj T., Parcy F.
Trends Plant Sci. 7:106-111(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[7]"Two-hybrid protein-protein interaction analysis in Arabidopsis protoplasts: establishment of a heterodimerization map of group C and group S bZIP transcription factors."
Ehlert A., Weltmeier F., Wang X., Mayer C.S., Smeekens S., Vicente-Carbajosa J., Droege-Laser W.
Plant J. 46:890-900(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH BZIP4; BZIP9; BZIP10; BZIP11; BZIP25; BZIP42; BZIP44; BZIP58 AND BZIP63.
[8]"Expression patterns within the Arabidopsis C/S1 bZIP transcription factor network: availability of heterodimerization partners controls gene expression during stress response and development."
Weltmeier F., Rahmani F., Ehlert A., Dietrich K., Schuetze K., Wang X., Chaban C., Hanson J., Teige M., Harter K., Vicente-Carbajosa J., Smeekens S., Droege-Laser W.
Plant Mol. Biol. 69:107-119(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, INDUCTION BY GLUCOSE AND PSEUDOMONAS SYRINGAE.
Strain: cv. Columbia.
[9]"The arabidopsis bZIP1 transcription factor is involved in sugar signaling, protein networking, and DNA binding."
Kang S.G., Price J., Lin P.-C., Hong J.C., Jang J.-C.
Mol. Plant 3:361-373(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY GLUCOSE AND MANNOSE, TISSUE SPECIFICITY, INTERACTION WITH ZFP7; BZIP10; BZIP11; BZIP25; BZIP44 AND BZIP63.
[10]"Heterodimers of the Arabidopsis transcription factors bZIP1 and bZIP53 reprogram amino acid metabolism during low energy stress."
Dietrich K., Weltmeier F., Ehlert A., Weiste C., Stahl M., Harter K., Droege-Laser W.
Plant Cell 23:381-395(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH BZIP53, INDUCTION BY STARVATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF400618 mRNA. Translation: AAK94022.1.
AB023034 Genomic DNA. Translation: BAB09915.1.
CP002688 Genomic DNA. Translation: AED95813.1.
AY136307 mRNA. Translation: AAM96973.1.
BT000400 mRNA. Translation: AAN15719.1.
AY088207 mRNA. Translation: AAM65749.1.
RefSeqNP_199756.1. NM_124322.3.
UniGeneAt.26573.

3D structure databases

ProteinModelPortalQ9FGX2.
SMRQ9FGX2. Positions 16-69.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9FGX2. 19 interactions.
STRING3702.AT5G49450.1-P.

Proteomic databases

PRIDEQ9FGX2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G49450.1; AT5G49450.1; AT5G49450.
GeneID835005.
KEGGath:AT5G49450.

Organism-specific databases

TAIRAT5G49450.

Phylogenomic databases

eggNOGNOG82287.
HOGENOMHOG000237945.
InParanoidQ9FGX2.
OMALENMIAT.
PhylomeDBQ9FGX2.

Gene expression databases

GenevestigatorQ9FGX2.

Family and domain databases

InterProIPR004827. bZIP.
[Graphical view]
PfamPF07716. bZIP_2. 1 hit.
[Graphical view]
SMARTSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBZIP1_ARATH
AccessionPrimary (citable) accession number: Q9FGX2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names