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Protein

Basic leucine zipper 1

Gene

BZIP1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcription factor that binds to the C-box-like motif (5'-TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters involved in sugar signaling. Activated by low energy stress both at transcriptional and post-transcriptional mechanisms. Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark-induced starvation response (PubMed:20080816, PubMed:21278122). Transcription activator of the mannan synthase CSLA9. Recognizes and binds to DNA-specific sequence of CSLA9 promoter (PubMed:24243147).3 Publications

GO - Molecular functioni

  • protein heterodimerization activity Source: UniProtKB
  • sequence-specific DNA binding Source: TAIR
  • transcription factor activity, sequence-specific DNA binding Source: UniProtKB
  • transcription regulatory region DNA binding Source: TAIR

GO - Biological processi

  • anther dehiscence Source: TAIR
  • cellular response to glucose stimulus Source: UniProtKB
  • cellular response to starvation Source: UniProtKB
  • positive regulation of transcription, DNA-templated Source: TAIR
  • regulation of cellular amino acid metabolic process Source: UniProtKB
  • response to bacterium Source: UniProtKB
  • response to osmotic stress Source: TAIR
  • response to salt stress Source: TAIR
  • sugar mediated signaling pathway Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Basic leucine zipper 1
Short name:
AtbZIP1
Short name:
bZIP protein 1
Gene namesi
Name:BZIP1
Ordered Locus Names:At5g49450
ORF Names:K7J8.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G49450.
TAIRilocus:2157999. AT5G49450.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Reduced requirement for exogenous sugar for seedling growth and higher rates of true leaf development.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004165571 – 145Basic leucine zipper 1Add BLAST145

Proteomic databases

PaxDbiQ9FGX2.

PTM databases

iPTMnetiQ9FGX2.

Expressioni

Tissue specificityi

Expressed in both shoots, including young leaves, stipulae and trichomes (except in cotyledons and hypocotyl), and roots, including vascular tissues (e.g. in both the phloem and the xylem). Present in seeds and pollen. Restricted to vasculatures and roots in the presence of sucrose or glucose.2 Publications

Developmental stagei

Expressed in seeds during late stage of development.1 Publication

Inductioni

Reversibly repressed by glucose and mannose. Slowly induced by Pseudomonas syringae. Induced in roots upon cold and salt stress but then repressed in leaves. Promoted by low energy stress and dark-induced starvation.3 Publications

Gene expression databases

ExpressionAtlasiQ9FGX2. differential.
GenevisibleiQ9FGX2. AT.

Interactioni

Subunit structurei

Interacts with ZFP7, BZIP4, BZIP9, BZIP10, BZIP11, BZIP25, BZIP42, BZIP44, BZIP53, BZIP58 and BZIP63.3 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • protein heterodimerization activity Source: UniProtKB

Protein-protein interaction databases

BioGridi20251. 10 interactors.
IntActiQ9FGX2. 21 interactors.
STRINGi3702.AT5G49450.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FGX2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 77bZIPPROSITE-ProRule annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni16 – 37Basic motifPROSITE-ProRule annotationAdd BLAST22
Regioni46 – 53Leucine-zipperPROSITE-ProRule annotation8

Sequence similaritiesi

Belongs to the bZIP family.Curated

Phylogenomic databases

eggNOGiENOG410JQTF. Eukaryota.
ENOG41115TY. LUCA.
HOGENOMiHOG000237945.
InParanoidiQ9FGX2.
OMAiLMEDTIH.
OrthoDBiEOG09360U7I.
PhylomeDBiQ9FGX2.

Family and domain databases

InterProiView protein in InterPro
IPR004827. bZIP.
PfamiView protein in Pfam
PF07716. bZIP_2. 1 hit.
SMARTiView protein in SMART
SM00338. BRLZ. 1 hit.
PROSITEiView protein in PROSITE
PS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9FGX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANAEKTSSG SDIDEKKRKR KLSNRESARR SRLKKQKLME DTIHEISSLE
60 70 80 90 100
RRIKENSERC RAVKQRLDSV ETENAGLRSE KIWLSSYVSD LENMIATTSL
110 120 130 140
TLTQSGGGDC VDDQNANAGI AVGDCRRTPW KLSCGSLQPM ASFKT
Length:145
Mass (Da):16,224
Last modified:March 1, 2001 - v1
Checksum:i5137A1CCE8638C0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF400618 mRNA. Translation: AAK94022.1.
AB023034 Genomic DNA. Translation: BAB09915.1.
CP002688 Genomic DNA. Translation: AED95813.1.
AY136307 mRNA. Translation: AAM96973.1.
BT000400 mRNA. Translation: AAN15719.1.
AY088207 mRNA. Translation: AAM65749.1.
RefSeqiNP_199756.1. NM_124322.3.
UniGeneiAt.26573.

Genome annotation databases

EnsemblPlantsiAT5G49450.1; AT5G49450.1; AT5G49450.
GeneIDi835005.
GrameneiAT5G49450.1; AT5G49450.1; AT5G49450.
KEGGiath:AT5G49450.

Similar proteinsi

Entry informationi

Entry nameiBZIP1_ARATH
AccessioniPrimary (citable) accession number: Q9FGX2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: March 1, 2001
Last modified: September 27, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families