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Q9FGR9 (CEP1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
KDEL-tailed cysteine endopeptidase CEP1

EC=3.4.22.-
Alternative name(s):
Cysteine proteinase CP56
Short name=AtCP56
Gene names
Name:CEP1
Synonyms:CP56
Ordered Locus Names:At5g50260
ORF Names:K6A12.12
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in the final stage of developmental programmed cell death and in intercalation of new cells. Cleaves extensins, thus probably supporing the final cell collapse By similarity. Ref.5

Subcellular location

Endoplasmic reticulum Probable.

Tissue specificity

Expressed in roots, stems, flowers, buds and green siliques. Found within columella, lateral root cap cells, and in the endodermis, the cortex and the epidermis during lateral root formation. Expressed in the abscission zones of the flower organs. Ref.5

Developmental stage

Expressed when organs wither and separate from the fruit or the green silique. Expressed in unpollinated, degrading ovules. Ref.5

Sequence similarities

Belongs to the peptidase C1 family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   Molecular functionHydrolase
Protease
Thiol protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentendoplasmic reticulum

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncysteine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 361341KDEL-tailed cysteine endopeptidase CEP1
PRO_0000403789

Regions

Motif358 – 3614Prevents secretion from ER Potential

Sites

Active site1501 By similarity
Active site2861 By similarity
Active site3071 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9FGR9 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: A622234BC3E7367A

FASTA36140,708
        10         20         30         40         50         60 
MKRFIVLALC MLMVLETTKG LDFHNKDVES ENSLWELYER WRSHHTVARS LEEKAKRFNV 

        70         80         90        100        110        120 
FKHNVKHIHE TNKKDKSYKL KLNKFGDMTS EEFRRTYAGS NIKHHRMFQG EKKATKSFMY 

       130        140        150        160        170        180 
ANVNTLPTSV DWRKNGAVTP VKNQGQCGSC WAFSTVVAVE GINQIRTKKL TSLSEQELVD 

       190        200        210        220        230        240 
CDTNQNQGCN GGLMDLAFEF IKEKGGLTSE LVYPYKASDE TCDTNKENAP VVSIDGHEDV 

       250        260        270        280        290        300 
PKNSEDDLMK AVANQPVSVA IDAGGSDFQF YSEGVFTGRC GTELNHGVAV VGYGTTIDGT 

       310        320        330        340        350        360 
KYWIVKNSWG EEWGEKGYIR MQRGIRHKEG LCGIAMEASY PLKNSNTNPS RLSLDSLKDE 


L 

« Hide

References

« Hide 'large scale' references
[1]"Function analysis of an Arabidopsis cysteine proteinase gene AtCP56 and the promoter ProCP56 in anther development."
Lv X., Li F., Lu H.
Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S.
DNA Res. 7:31-63(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"KDEL-tailed cysteine endopeptidases involved in programmed cell death, intercalation of new cells, and dismantling of extensin scaffolds."
Helm M., Schmid M., Hierl G., Terneus K., Tan L., Lottspeich F., Kieliszewski M.J., Gietl C.
Am. J. Bot. 95:1049-1062(2008)
Cited for: FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HM367092 mRNA. Translation: ADO14465.1.
AB024031 Genomic DNA. Translation: BAB09397.1.
CP002688 Genomic DNA. Translation: AED95919.1.
AY091087 mRNA. Translation: AAM13907.1.
RefSeqNP_568722.1. NM_124405.2.
UniGeneAt.7918.

3D structure databases

ProteinModelPortalQ9FGR9.
SMRQ9FGR9. Positions 31-350.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G50260.1-P.

Protein family/group databases

MEROPSC01.A03.

Proteomic databases

PaxDbQ9FGR9.
PRIDEQ9FGR9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G50260.1; AT5G50260.1; AT5G50260.
GeneID835091.
KEGGath:AT5G50260.

Organism-specific databases

TAIRAT5G50260.

Phylogenomic databases

eggNOGCOG4870.
HOGENOMHOG000230773.
InParanoidQ9FGR9.
KOK16292.
OMAAEDAYPY.
PhylomeDBQ9FGR9.

Enzyme and pathway databases

BioCycARA:AT5G50260-MONOMER.

Gene expression databases

GenevestigatorQ9FGR9.

Family and domain databases

InterProIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERPTHR12411. PTHR12411. 1 hit.
PfamPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSPR00705. PAPAIN.
SMARTSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEPS00014. ER_TARGET. 1 hit.
PS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCEP1_ARATH
AccessionPrimary (citable) accession number: Q9FGR9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: March 1, 2001
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names