Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9FG61

- P2C74_ARATH

UniProt

Q9FG61 - P2C74_ARATH

Protein

Probable protein phosphatase 2C 74

Gene

At5g36250

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi103 – 1031Manganese 1By similarity
    Metal bindingi103 – 1031Manganese 2By similarity
    Metal bindingi104 – 1041Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi329 – 3291Manganese 2By similarity
    Metal bindingi375 – 3751Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: TAIR
    3. protein binding Source: IntAct

    GO - Biological processi

    1. protein dephosphorylation Source: TAIR

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G36250-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 74 (EC:3.1.3.16)
    Short name:
    AtPP2C74
    Gene namesi
    Ordered Locus Names:At5g36250
    ORF Names:T30G6.11
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G36250.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: TAIR
    2. plasma membrane Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 448448Probable protein phosphatase 2C 74PRO_0000367994Add
    BLAST

    Proteomic databases

    PRIDEiQ9FG61.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9FG61.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    At3g01090B9DFC12EBI-4437407,EBI-7801898

    Protein-protein interaction databases

    BioGridi18873. 1 interaction.
    IntActiQ9FG61. 4 interactions.
    MINTiMINT-8312718.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9FG61.
    SMRiQ9FG61. Positions 72-346.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini206 – 344139PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233897.
    InParanoidiQ9FG61.
    OMAiGHIVAKR.
    PhylomeDBiQ9FG61.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q9FG61-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSCLSSSGG GGSRRSLHGS PHVPGPGRRK RPPKRRPGSC SSSFDNTEEP    50
    LLHRIPGRMF LNGSTDTVSL FSQQGKKGPN QDAMIVWENF GSMEDTVFCG 100
    VFDGHGPYGH IVAKRVRDLL PLKLGSHLES YVSPEEVLKE ISLNTDDRKI 150
    SEDLVHISAN GESRVYNKDY VKDQDMIQML IGSIVKAYRF MDKELKMQVD 200
    VDCFCSGTTA VTMVKQGQHL VIGNIGDSRA VLGVRNKDNK LVPFQLTEDL 250
    KPDVPAEAER IKRCRGRIFA LRDEPGVARL WLPNHNSPGL AMARAFGDFC 300
    LKDFGLISVP DVSYRRLTEK DEFVVLATDG IWDALTNEEV VKIVAKAPTR 350
    SSAGRALVEA AVRNWRWKFP TSKVDDCAVV CLFLDSEPNR LSTASFSKEK 400
    HINNGVTEPE PDTASSSTPD SGTGSPELNG VNRIDTLVNL PVYVPTKE 448
    Length:448
    Mass (Da):49,314
    Last modified:March 1, 2001 - v1
    Checksum:iF60D6EA773B718C9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti57 – 571G → E in AAM47343. (PubMed:14593172)Curated
    Sequence conflicti57 – 571G → E in AAL31255. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB026661 Genomic DNA. Translation: BAB09365.1.
    CP002688 Genomic DNA. Translation: AED94062.1.
    AY061752 mRNA. Translation: AAL31255.1.
    AY113035 mRNA. Translation: AAM47343.1.
    RefSeqiNP_198474.1. NM_123016.1.
    UniGeneiAt.27370.

    Genome annotation databases

    EnsemblPlantsiAT5G36250.1; AT5G36250.1; AT5G36250.
    GeneIDi833622.
    KEGGiath:AT5G36250.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB026661 Genomic DNA. Translation: BAB09365.1 .
    CP002688 Genomic DNA. Translation: AED94062.1 .
    AY061752 mRNA. Translation: AAL31255.1 .
    AY113035 mRNA. Translation: AAM47343.1 .
    RefSeqi NP_198474.1. NM_123016.1.
    UniGenei At.27370.

    3D structure databases

    ProteinModelPortali Q9FG61.
    SMRi Q9FG61. Positions 72-346.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 18873. 1 interaction.
    IntActi Q9FG61. 4 interactions.
    MINTi MINT-8312718.

    Proteomic databases

    PRIDEi Q9FG61.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G36250.1 ; AT5G36250.1 ; AT5G36250 .
    GeneIDi 833622.
    KEGGi ath:AT5G36250.

    Organism-specific databases

    TAIRi AT5G36250.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233897.
    InParanoidi Q9FG61.
    OMAi GHIVAKR.
    PhylomeDBi Q9FG61.

    Enzyme and pathway databases

    BioCyci ARA:AT5G36250-MONOMER.

    Gene expression databases

    Genevestigatori Q9FG61.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 5. XI."
      Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
      Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C74_ARATH
    AccessioniPrimary (citable) accession number: Q9FG61
    Secondary accession number(s): Q8W4Q9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3