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Q9FG61 (P2C74_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 74

Short name=AtPP2C74
EC=3.1.3.16
Gene names
Ordered Locus Names:At5g36250
ORF Names:T30G6.11
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

AT3G01090B9DFC12EBI-4437407,EBI-7801898

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Probable protein phosphatase 2C 74
PRO_0000367994

Regions

Domain206 – 344139PP2C-like

Sites

Metal binding1031Manganese 1 By similarity
Metal binding1031Manganese 2 By similarity
Metal binding1041Manganese 1; via carbonyl oxygen By similarity
Metal binding3291Manganese 2 By similarity
Metal binding3751Manganese 2 By similarity

Experimental info

Sequence conflict571G → E in AAM47343. Ref.3
Sequence conflict571G → E in AAL31255. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q9FG61 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: F60D6EA773B718C9

FASTA44849,314
        10         20         30         40         50         60 
MGSCLSSSGG GGSRRSLHGS PHVPGPGRRK RPPKRRPGSC SSSFDNTEEP LLHRIPGRMF 

        70         80         90        100        110        120 
LNGSTDTVSL FSQQGKKGPN QDAMIVWENF GSMEDTVFCG VFDGHGPYGH IVAKRVRDLL 

       130        140        150        160        170        180 
PLKLGSHLES YVSPEEVLKE ISLNTDDRKI SEDLVHISAN GESRVYNKDY VKDQDMIQML 

       190        200        210        220        230        240 
IGSIVKAYRF MDKELKMQVD VDCFCSGTTA VTMVKQGQHL VIGNIGDSRA VLGVRNKDNK 

       250        260        270        280        290        300 
LVPFQLTEDL KPDVPAEAER IKRCRGRIFA LRDEPGVARL WLPNHNSPGL AMARAFGDFC 

       310        320        330        340        350        360 
LKDFGLISVP DVSYRRLTEK DEFVVLATDG IWDALTNEEV VKIVAKAPTR SSAGRALVEA 

       370        380        390        400        410        420 
AVRNWRWKFP TSKVDDCAVV CLFLDSEPNR LSTASFSKEK HINNGVTEPE PDTASSSTPD 

       430        440 
SGTGSPELNG VNRIDTLVNL PVYVPTKE 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. XI."
Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB026661 Genomic DNA. Translation: BAB09365.1.
CP002688 Genomic DNA. Translation: AED94062.1.
AY061752 mRNA. Translation: AAL31255.1.
AY113035 mRNA. Translation: AAM47343.1.
RefSeqNP_198474.1. NM_123016.1.
UniGeneAt.27370.

3D structure databases

ProteinModelPortalQ9FG61.
SMRQ9FG61. Positions 72-346.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid18873. 1 interaction.
IntActQ9FG61. 4 interactions.
MINTMINT-8312718.

Proteomic databases

PRIDEQ9FG61.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G36250.1; AT5G36250.1; AT5G36250.
GeneID833622.
KEGGath:AT5G36250.

Organism-specific databases

TAIRAT5G36250.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000233897.
InParanoidQ9FG61.
OMAGHIVAKR.
PhylomeDBQ9FG61.

Enzyme and pathway databases

BioCycARA:AT5G36250-MONOMER.

Gene expression databases

GenevestigatorQ9FG61.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 2 hits.
ProtoNetSearch...

Entry information

Entry nameP2C74_ARATH
AccessionPrimary (citable) accession number: Q9FG61
Secondary accession number(s): Q8W4Q9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names