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Q9FG59

- DHAR4_ARATH

UniProt

Q9FG59 - DHAR4_ARATH

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Protein

Putative glutathione S-transferase DHAR4

Gene

DHAR4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Protein uncertaini

Functioni

Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei20 – 201By similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC

GO - Biological processi

  1. response to toxic substance Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutathione S-transferase DHAR4 (EC:2.5.1.18)
Alternative name(s):
Chloride intracellular channel homolog 4
Short name:
CLIC homolog 4
Glutathione-dependent dehydroascorbate reductase 4
Short name:
AtDHAR4
Short name:
GSH-dependent dehydroascorbate reductase 4
Gene namesi
Name:DHAR4
Ordered Locus Names:At5g36270
ORF Names:T30G6.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G36270.

Subcellular locationi

Cytoplasmcytosol Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 217217Putative glutathione S-transferase DHAR4PRO_0000395484Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ9FG59.

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9FG59.
SMRiQ9FG59. Positions 3-200.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 8576GST N-terminalAdd
BLAST
Domaini86 – 217132GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 212Glutathione bindingBy similarity
Regioni46 – 472Glutathione bindingBy similarity
Regioni59 – 602Glutathione bindingBy similarity
Regioni74 – 752Glutathione bindingBy similarity

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi20 – 256Glutathione-bindingSequence Analysis

Sequence similaritiesi

Belongs to the GST superfamily. DHAR family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

InParanoidiQ9FG59.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9FG59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGIEVCVKAA SGAPDVLGDC PFGQRILLTL EDKKLPYKTH LIDVSLKPDW
60 70 80 90 100
FLAISPKGKL PLVKFDEDEN WVADSDLIVG IIEEKYPEPS LVTFPPEFAS
110 120 130 140 150
VGSKIIGAFV MFLTSKDHAN DGSDMALLDE LEALDHHLKT HVGPFVAGDK
160 170 180 190 200
VTVVDLSLAP KLYHLETTLG HFMDWCVPES LTNVRDYMKV LFSLESFEKT
210
KAAKEYLIAS WAPKLDV
Length:217
Mass (Da):24,060
Last modified:March 1, 2001 - v1
Checksum:iFA21044464FDB0EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026661 Genomic DNA. Translation: BAB09367.1.
CP002688 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026661 Genomic DNA. Translation: BAB09367.1 .
CP002688 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali Q9FG59.
SMRi Q9FG59. Positions 3-200.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

TAIRi AT5G36270.

Phylogenomic databases

InParanoidi Q9FG59.

Gene expression databases

Genevestigatori Q9FG59.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF13417. GST_N_3. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 5. XI."
    Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
    Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana."
    Dixon D.P., Davis B.G., Edwards R.
    J. Biol. Chem. 277:30859-30869(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiDHAR4_ARATH
AccessioniPrimary (citable) accession number: Q9FG59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3