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Protein

Transcription factor MYB75

Gene

MYB75

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcription activator, when associated with BHLH12/MYC1, EGL3, or GL3. Promotes the synthesis of. phenylpropanoid-derived compounds such as anthocyanins and proanthocyanidin, probably together with GL3 and BHLH2. Regulates the expression of CHS, DFRA, LDOX, and BAN.6 Publications

Miscellaneous

This protein has reduced anthocyanins induction activity in cv C24 and cv cvi-1 backgrounds.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi33 – 57H-T-H motifPROSITE-ProRule annotationAdd BLAST25
DNA bindingi85 – 108H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

  • anthocyanin-containing compound biosynthetic process Source: TAIR
  • cell differentiation Source: GO_Central
  • defense response to fungus Source: TAIR
  • jasmonic acid mediated signaling pathway Source: TAIR
  • positive regulation of anthocyanin biosynthetic process Source: TAIR
  • regulation of anthocyanin biosynthetic process Source: TAIR
  • regulation of transcription from RNA polymerase II promoter Source: GO_Central
  • removal of superoxide radicals Source: TAIR
  • response to auxin Source: TAIR
  • response to ethylene Source: TAIR
  • response to jasmonic acid Source: TAIR
  • response to salt stress Source: TAIR
  • sucrose mediated signaling Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor MYB75
Alternative name(s):
Myb-related protein 75
Short name:
AtMYB75
Production of anthocyanin pigment 1 protein
Suc-induced anthocyanin accumulation locus 1
Gene namesi
Name:MYB75
Synonyms:PAP1, SIAA1
Ordered Locus Names:At1g56650
ORF Names:F25P12.92
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G56650.
TAIRilocus:2027523. AT1G56650.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002857301 – 248Transcription factor MYB75Add BLAST248

Proteomic databases

PaxDbiQ9FE25.

Expressioni

Tissue specificityi

Mostly expressed in mature plant aerial part. Detected ubiquitously, with higher levels in rosette leaves and flowers.2 Publications

Inductioni

By jasmonic acid (JA), NaCl, sucrose, UV light, nitrogen deficiency and drought.3 Publications

Gene expression databases

GenevisibleiQ9FE25. AT.

Interactioni

Subunit structurei

Interacts with BHLH12/MYC1, BHLH1/GL3/MYC6, BHLH2/EGL3/MYC146, and BHLH42/TT8.2 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi27345. 15 interactors.
IntActiQ9FE25. 53 interactors.
STRINGi3702.AT1G56650.1.

Structurei

3D structure databases

ProteinModelPortaliQ9FE25.
SMRiQ9FE25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 57HTH myb-type 1PROSITE-ProRule annotationAdd BLAST53
Domaini58 – 112HTH myb-type 2PROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0048. Eukaryota.
COG5147. LUCA.
HOGENOMiHOG000237600.
InParanoidiQ9FE25.
KOiK16166.
OMAiHEPCCKI.
OrthoDBiEOG09360TBI.
PhylomeDBiQ9FE25.

Family and domain databases

CDDicd00167. SANT. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR017930. Myb_dom.
IPR001005. SANT/Myb.
PfamiView protein in Pfam
PF00249. Myb_DNA-binding. 2 hits.
SMARTiView protein in SMART
SM00717. SANT. 2 hits.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS51294. HTH_MYB. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9FE25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGSSKGLRK GAWTTEEDSL LRQCINKYGE GKWHQVPVRA GLNRCRKSCR
60 70 80 90 100
LRWLNYLKPS IKRGKLSSDE VDLLLRLHRL LGNRWSLIAG RLPGRTANDV
110 120 130 140 150
KNYWNTHLSK KHEPCCKIKM KKRDITPIPT TPALKNNVYK PRPRSFTVNN
160 170 180 190 200
DCNHLNAPPK VDVNPPCLGL NINNVCDNSI IYNKDKKKDQ LVNNLIDGDN
210 220 230 240
MWLEKFLEES QEVDILVPEA TTTEKGDTLA FDVDQLWSLF DGETVKFD
Length:248
Mass (Da):28,470
Last modified:March 1, 2001 - v1
Checksum:iB86103A9AB5CF442
GO

Sequence cautioni

The sequence AAC83630 differs from that shown. Reason: Frameshift at position 207.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti246 – 247KF → EL in AAS10033 (Ref. 4) Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti37P → H in strain: cv. cvi-1. 1 Publication1
Natural varianti60S → N in strain: cv. Landsberg erecta. 1 Publication1
Natural varianti136N → T in strain: cv. C24 and cv. Landsberg erecta. 1 Publication1
Natural varianti147 – 148TV → SG in strain: cv. Landsberg erecta. 2
Natural varianti147T → S in strain: cv. C24. 1 Publication1
Natural varianti160K → N in strain: cv. cvi-1. 1 Publication1
Natural varianti167C → R in strain: cv. C24. 1 Publication1
Natural varianti172I → T in strain: cv. C24 and cv. Landsberg erecta. 1 Publication1
Natural varianti179S → N in strain: cv. C24 and cv. Landsberg erecta. 1 Publication1
Natural varianti215I → M in strain: cv. C24 and cv. Landsberg erecta. 1 Publication1
Natural varianti220A → T in strain: cv. C24 and cv. Landsberg erecta. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF062908 mRNA. Translation: AAC83630.1. Frameshift.
AF325123 Genomic DNA. Translation: AAG42001.1.
DQ222404 Genomic DNA. Translation: ABB03877.1.
DQ222405 Genomic DNA. Translation: ABB03878.1.
DQ222406 Genomic DNA. Translation: ABB03879.1.
AY519563 mRNA. Translation: AAS10033.1.
AC009323 Genomic DNA. Translation: AAG09100.1.
CP002684 Genomic DNA. Translation: AEE33419.1.
AK221639 mRNA. Translation: BAD95284.1.
PIRiB96608.
T51680.
RefSeqiNP_176057.1. NM_104541.4.
UniGeneiAt.20447.

Genome annotation databases

EnsemblPlantsiAT1G56650.1; AT1G56650.1; AT1G56650.
GeneIDi842120.
GrameneiAT1G56650.1; AT1G56650.1; AT1G56650.
KEGGiath:AT1G56650.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiMYB75_ARATH
AccessioniPrimary (citable) accession number: Q9FE25
Secondary accession number(s): Q38JL3
, Q38JL4, Q38JL5, Q6R0B5, Q9ZTC7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: March 1, 2001
Last modified: November 22, 2017
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names