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Q9FDS0

- Q9FDS0_STRCS

UniProt

Q9FDS0 - Q9FDS0_STRCS

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Protein
Submitted name:

Neutral proteinase inhibitor ScNPI

Gene
ScNPI
Organism
Streptomyces caespitosus
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei31 – 311CacodylateImported
Binding sitei109 – 1091Acetate 3Imported
Metal bindingi121 – 1211Potassium 1; via pros nitrogenImported
Metal bindingi121 – 1211Potassium 2; via tele nitrogenImported
Binding sitei121 – 1211Acetate 2Imported
Metal bindingi132 – 1321Potassium 2Imported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitorUniRule annotation

Keywords - Ligandi

Metal-bindingImported, PotassiumImported

Protein family/group databases

MEROPSiI16.017.

Names & Taxonomyi

Protein namesi
Submitted name:
Neutral proteinase inhibitor ScNPIImported
Gene namesi
Name:ScNPIImported
OrganismiStreptomyces caespitosusImported
Taxonomic identifieri53502 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HWXX-ray1.90A29-141[»]
4HX2X-ray2.25B/D29-141[»]
4HX3X-ray2.70B/D/F/H/J/L29-141[»]
ProteinModelPortaliQ9FDS0.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni30 – 312Acetate 1 bindingImported
Regioni116 – 1194Acetate 3 bindingImported

Sequence similaritiesi

Family and domain databases

Gene3Di3.30.350.10. 1 hit.
InterProiIPR000691. Prot_inh_I16_SSI.
IPR023549. Subtilisin_inhibitor.
[Graphical view]
PfamiPF00720. SSI. 1 hit.
[Graphical view]
PRINTSiPR00294. SSBTLNINHBTR.
ProDomiPD004028. Prot_inh_SSI. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55399. SSF55399. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9FDS0-1 [UniParc]FASTAAdd to Basket

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MRHHVIAVSA LSLLCLAGST GLAEAQPASA HGPSAMVFTV IQGSGEPTDT    50
VLRATTLSCA YTAEGTHPAP RAACDALNAT DGELNRLLAA PDPSLVCPMY 100
FDPVTVTADG VLNGRRVAWK HTFSNTCVMS ANLNSNPVYA F 141
Length:141
Mass (Da):14,657
Last modified:March 1, 2001 - v1
Checksum:iBEB8C40E3D22ECF6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB042804 Genomic DNA. Translation: BAB11977.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB042804 Genomic DNA. Translation: BAB11977.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HWX X-ray 1.90 A 29-141 [» ]
4HX2 X-ray 2.25 B/D 29-141 [» ]
4HX3 X-ray 2.70 B/D/F/H/J/L 29-141 [» ]
ProteinModelPortali Q9FDS0.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I16.017.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.30.350.10. 1 hit.
InterProi IPR000691. Prot_inh_I16_SSI.
IPR023549. Subtilisin_inhibitor.
[Graphical view ]
Pfami PF00720. SSI. 1 hit.
[Graphical view ]
PRINTSi PR00294. SSBTLNINHBTR.
ProDomi PD004028. Prot_inh_SSI. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF55399. SSF55399. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A novel double-headed proteinaceous inhibitor for metalloproteinase and serine proteinase."
    Hiraga K., Suzuki T., Oda K.
    J. Biol. Chem. 275:25173-25179(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9FDS0_STRCS
AccessioniPrimary (citable) accession number: Q9FDS0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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