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Q9FDF2

- Q9FDF2_BACLI

UniProt

Q9FDF2 - Q9FDF2_BACLI

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Protein
Submitted name:

KerA

Gene
N/A
Organism
Bacillus licheniformis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi38 – 381Calcium 1Combined sources
Metal bindingi77 – 771Calcium 1Combined sources
Metal bindingi110 – 1101Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi112 – 1121Calcium 1Combined sources
Metal bindingi114 – 1141Calcium 1; via carbonyl oxygenCombined sources
Metal bindingi116 – 1161Calcium 1; via carbonyl oxygenCombined sources
Binding sitei152 – 1521Acetate; via carbonyl oxygenCombined sources
Metal bindingi204 – 2041Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi206 – 2061Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi209 – 2091Calcium 2; via carbonyl oxygenCombined sources
Metal bindingi273 – 2731Zinc; via tele nitrogenCombined sources
Metal bindingi310 – 3101ZincCombined sources

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. serine-type endopeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotation

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
KerAImported
OrganismiBacillus licheniformisImported
Taxonomic identifieri1402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4GI3X-ray1.75A37-310[»]
4HX2X-ray2.25A/C37-310[»]
ProteinModelPortaliQ9FDF2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.200. 1 hit.
InterProiIPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR010259. S8pro/Inhibitor_I9.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF05922. Inhibitor_I9. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9FDF2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
RIINAAKAKL DKEALKEVKN DPDVAYVEED HVAHALAQTV PYGIPLIKAD
60 70 80 90 100
KVQAQGFKGA NVKVAVLDTG IQASHPDLNV VGGASFVAGE AYNTDGNGHG
110 120 130 140 150
THVAGTVAAL DNTTGVLGVA PSVSLYAVKV LNSSGSGSYS GIVSGIEWAT
160 170 180 190 200
TNGMDVINMS LGGASGSTAM KQAVDNAYAR GVVVVAAAGN SGSSGNTNTI
210 220 230 240 250
GYPAKYDSVI AVGAVDSNSN RASFSSVGAE LEVMAPGAGV YSTYPTNTYA
260 270 280 290 300
TLNGTSMASP HVAGAAALIL SKHPNLSASQ VRNRLSSTAT YLGSSFYYGK
310
GLINVEAAAQ
Length:310
Mass (Da):31,285
Last modified:March 1, 2001 - v1
Checksum:i740B9816277876EA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF282895 Genomic DNA. Translation: AAG00494.1.
PIRiJC1085.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF282895 Genomic DNA. Translation: AAG00494.1 .
PIRi JC1085.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4GI3 X-ray 1.75 A 37-310 [» ]
4HX2 X-ray 2.25 A/C 37-310 [» ]
ProteinModelPortali Q9FDF2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.200. 1 hit.
InterProi IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR010259. S8pro/Inhibitor_I9.
[Graphical view ]
PANTHERi PTHR10795. PTHR10795. 1 hit.
Pfami PF05922. Inhibitor_I9. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view ]
PRINTSi PR00723. SUBTILISIN.
SUPFAMi SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of kerA gene encoding a keratinolytic protease of Bacillus licheniformis OWU 837B."
    Goldstein G., Wagner E.K., Lee Y.E., Masisak E.S., Oh J.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 837BImported.
  2. "Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin."
    Derache C., Epinette C., Roussel A., Gabant G., Cadene M., Korkmaz B., Gauthier F., Kellenberger C.
    FEBS J. 279:4466-4478(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 37-310.

Entry informationi

Entry nameiQ9FDF2_BACLI
AccessioniPrimary (citable) accession number: Q9FDF2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: January 7, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.