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Q9FDF2

- Q9FDF2_BACLI

UniProt

Q9FDF2 - Q9FDF2_BACLI

Protein
Submitted name:

KerA

Gene
N/A
Organism
Bacillus licheniformis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi38 – 381Calcium 1Imported
    Metal bindingi77 – 771Calcium 1Imported
    Metal bindingi110 – 1101Calcium 1; via carbonyl oxygenImported
    Metal bindingi112 – 1121Calcium 1Imported
    Metal bindingi114 – 1141Calcium 1; via carbonyl oxygenImported
    Metal bindingi116 – 1161Calcium 1; via carbonyl oxygenImported
    Binding sitei152 – 1521Acetate; via carbonyl oxygenImported
    Metal bindingi204 – 2041Calcium 2; via carbonyl oxygenImported
    Metal bindingi204 – 2041Calcium 3; via carbonyl oxygen
    Metal bindingi206 – 2061Calcium 2; via carbonyl oxygenImported
    Metal bindingi206 – 2061Calcium 3; via carbonyl oxygen
    Metal bindingi209 – 2091Calcium 2; via carbonyl oxygenImported
    Metal bindingi209 – 2091Calcium 3; via carbonyl oxygen
    Metal bindingi273 – 2731Zinc; via tele nitrogenImported
    Metal bindingi310 – 3101ZincImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. serine-type endopeptidase activity Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine proteaseUniRule annotation

    Keywords - Ligandi

    CalciumImported, Metal-bindingImported, ZincImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    KerAImported
    OrganismiBacillus licheniformisImported
    Taxonomic identifieri1402 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4GI3X-ray1.75A37-310[»]
    4HX2X-ray2.25A/C37-310[»]
    ProteinModelPortaliQ9FDF2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S8 family.UniRule annotation

    Family and domain databases

    Gene3Di3.40.50.200. 1 hit.
    InterProiIPR010259. Inhibitor_I9.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR009020. Prot_inh_propept.
    [Graphical view]
    PANTHERiPTHR10795. PTHR10795. 1 hit.
    PfamiPF05922. Inhibitor_I9. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    [Graphical view]
    PRINTSiPR00723. SUBTILISIN.
    SUPFAMiSSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9FDF2-1 [UniParc]FASTAAdd to Basket

    « Hide

    RIINAAKAKL DKEALKEVKN DPDVAYVEED HVAHALAQTV PYGIPLIKAD    50
    KVQAQGFKGA NVKVAVLDTG IQASHPDLNV VGGASFVAGE AYNTDGNGHG 100
    THVAGTVAAL DNTTGVLGVA PSVSLYAVKV LNSSGSGSYS GIVSGIEWAT 150
    TNGMDVINMS LGGASGSTAM KQAVDNAYAR GVVVVAAAGN SGSSGNTNTI 200
    GYPAKYDSVI AVGAVDSNSN RASFSSVGAE LEVMAPGAGV YSTYPTNTYA 250
    TLNGTSMASP HVAGAAALIL SKHPNLSASQ VRNRLSSTAT YLGSSFYYGK 300
    GLINVEAAAQ 310
    Length:310
    Mass (Da):31,285
    Last modified:March 1, 2001 - v1
    Checksum:i740B9816277876EA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF282895 Genomic DNA. Translation: AAG00494.1.
    PIRiJC1085.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF282895 Genomic DNA. Translation: AAG00494.1 .
    PIRi JC1085.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4GI3 X-ray 1.75 A 37-310 [» ]
    4HX2 X-ray 2.25 A/C 37-310 [» ]
    ProteinModelPortali Q9FDF2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.200. 1 hit.
    InterProi IPR010259. Inhibitor_I9.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR009020. Prot_inh_propept.
    [Graphical view ]
    PANTHERi PTHR10795. PTHR10795. 1 hit.
    Pfami PF05922. Inhibitor_I9. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    [Graphical view ]
    PRINTSi PR00723. SUBTILISIN.
    SUPFAMi SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of kerA gene encoding a keratinolytic protease of Bacillus licheniformis OWU 837B."
      Goldstein G., Wagner E.K., Lee Y.E., Masisak E.S., Oh J.
      Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 837BImported.
    2. "Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin."
      Derache C., Epinette C., Roussel A., Gabant G., Cadene M., Korkmaz B., Gauthier F., Kellenberger C.
      FEBS J. 279:4466-4478(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 37-310.

    Entry informationi

    Entry nameiQ9FDF2_BACLI
    AccessioniPrimary (citable) accession number: Q9FDF2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3