Q9FDF2 (Q9FDF2_BACLI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: KerA EMBL AAG00494.1
Organism	Bacillus licheniformis EMBL AAG00494.1
Taxonomic identifier	1402 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus subtilis group

Protein attributes

Sequence length	310 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S8 family. RuleBase RU003355

Ontologies

Keywords
Molecular function	Hydrolase Protease Serine protease RuleBase RU004261
Technical term	3D-structure PDB 4GI3 PDB 4HX2
Gene Ontology (GO)
Biological_process	negative regulation of catalytic activity Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAG00494.1

Sequences

	Sequence		Length	Mass (Da)
	Q9FDF2 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 740B9816277876EA	FASTA	310	31,285
	10 20 30 40 50 60 RIINAAKAKL DKEALKEVKN DPDVAYVEED HVAHALAQTV PYGIPLIKAD KVQAQGFKGA 70 80 90 100 110 120 NVKVAVLDTG IQASHPDLNV VGGASFVAGE AYNTDGNGHG THVAGTVAAL DNTTGVLGVA 130 140 150 160 170 180 PSVSLYAVKV LNSSGSGSYS GIVSGIEWAT TNGMDVINMS LGGASGSTAM KQAVDNAYAR 190 200 210 220 230 240 GVVVVAAAGN SGSSGNTNTI GYPAKYDSVI AVGAVDSNSN RASFSSVGAE LEVMAPGAGV 250 260 270 280 290 300 YSTYPTNTYA TLNGTSMASP HVAGAAALIL SKHPNLSASQ VRNRLSSTAT YLGSSFYYGK 310 GLINVEAAAQ

References

[1]	"Nucleotide sequence of kerA gene encoding a keratinolytic protease of Bacillus licheniformis OWU 837B." Goldstein G., Wagner E.K., Lee Y.E., Masisak E.S., Oh J. Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 837B EMBL AAG00494.1.
[2]	"Crystal structure of Greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin." Derache C., Epinette C., Roussel A., Gabant G., Cadene M., Korkmaz B., Gauthier F., Kellenberger C. Submitted (AUG-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 37-310.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF282895 Genomic DNA. Translation: AAG00494.1.

PIR

JC1085.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4GI3	X-ray	1.75	A	37-310	[»]
4HX2	X-ray	2.25	A/C	37-310	[»]

HSSP

HSSP built from PDB template 1C3L based on UniProtKB P00780.

ProteinModelPortal

Q9FDF2.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

3.40.50.200. 1 hit.

InterPro

IPR010259. Inhibitor_I9.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
[Graphical view]

PANTHER

PTHR10795. PTHR10795. 1 hit.

Pfam

PF05922. Inhibitor_I9. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]

PRINTS

PR00723. SUBTILISIN.

SUPFAM

SSF52743. Pept_S8_S53. 1 hit.
SSF54897. Prot_inh_propept. 1 hit.

PROSITE

PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9FDF2_BACLI

Accession

Primary (citable) accession number: Q9FDF2

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)