ID   Q9FCG8_STRCO            Unreviewed;       544 AA.
AC   Q9FCG8;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 120.
DE   RecName: Full=Response regulatory domain-containing protein {ECO:0000259|PROSITE:PS50110};
GN   OrderedLocusNames=SCO4201 {ECO:0000313|EMBL:CAC04037.1};
GN   ORFNames=2SCD46.15c {ECO:0000313|EMBL:CAC04037.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAC04037.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAC04037.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939119; CAC04037.1; -; Genomic_DNA.
DR   RefSeq; NP_628376.1; NC_003888.3.
DR   AlphaFoldDB; Q9FCG8; -.
DR   STRING; 100226.gene:17761845; -.
DR   PaxDb; 100226-SCO4201; -.
DR   PATRIC; fig|100226.15.peg.4265; -.
DR   eggNOG; COG2197; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_035411_0_0_11; -.
DR   InParanoid; Q9FCG8; -.
DR   OrthoDB; 5181538at2; -.
DR   PhylomeDB; Q9FCG8; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT   DOMAIN          144..280
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   REGION          1..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          201..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..107
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         194
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   544 AA;  57814 MW;  CABF18D66E5606F1 CRC64;
     MALGRPTCSG PFRSGAVTRY GPRRWVEVPR PAMPSGGGKE PKTMPVPVPR QRAIPAVECG
     QAPAASPDSG PSKEQAPPGT HQAENAATRR ENTRENPTEK REKPTDTSTE TSTGTSSGTG
     TGTGTDRTPA PGVRAESAAP TNLTVLLIED DPAGSPIVPD LLDQSGKPIR VRTARNLTEA
     GRLLTDDVHC ILLDLALSAP APARTNTDGG GSGNGGDAEG DDELAVLRHV LELAPRHAVL
     ALTSSSDAER GAEAVAVGAQ DYLFRDELDG RLLSRAIRYA VERKRSDSAE RRLAEGRLRA
     QENRRLERGL LPTPLLAGSP LRFAARYRPG RSRALLGGDF YDVVRTPDGT VHAMIGDVCG
     HGPDEAALGV ELRIAWRALT LAGLCGDELL GTLQQVLEHE RSDDEIFATL CAVDISPDGR
     RAGLCLAGHP SPLLSRPGTP ARLLPYDNNG PALGLLPGAR WPRMQVELGA EWSLMLYTDG
     LIEGHVGGGR ERLGQDGMVE LVRRQRAEGL TGEELLRATV NEVRELNGGE LADDLAVVLL
     DRTA
//