Q9FBR4 (Q9FBR4_STRCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative 2-oxoglutarate dehydrogenase EMBL CAC04496.1

Gene names

Ordered Locus Names:

SCO5281

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	1272 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9FBR4 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: FEC500479C586A64	FASTA	1,272	139,208
	10 20 30 40 50 60 MSPQSPSNSS ISTDTDQAGT AGKNPAAAFG ANEWLVDEIY QQYLQDPNSV DRAWWDFFAD 70 80 90 100 110 120 YKPGAAATPT AAGTVPTDAG STPPAAPAPR AQAPAQPQAA APAPAPAKPA AAAPAAPAAP 130 140 150 160 170 180 ATKPAAAPAK PAAKPQAKAA APAKDAGAAP EGPELVTLRG PAAAVAKNMN ASLELPTATS 190 200 210 220 230 240 VRAVPVKLLF DNRIVINNHL KRARGGKISF THLIGYAMVQ AIKAMPTMNH SFGEKDGKPT 250 260 270 280 290 300 LVKPAHINLG LAIDLVKPNG DRQLVVAAIK KAETLNFFEF WQAYEDIVRR ARDNKLTMDD 310 320 330 340 350 360 FTGVTVSLTN PGGLGTVHSV PRLMPGQSVI LGVGSMDYPA EFQGTSQDTL NKLGISKVMT 370 380 390 400 410 420 LTSTYDHRVI QGAASGEFLR QVANLLLGEN GFYDDIFKAL RIPYEPVRWL KDIDASHDDD 430 440 450 460 470 480 VTKAARVFEL IHSYRVRGHV MADTDPLEYQ QRKHPDLDIT EHGLTLWDLE REFAVGGFAG 490 500 510 520 530 540 KSLMKLRDIL GVLRDSYCRT TGVEFMHIQD PKQRKWIQDR IERSHTKPER EEQLRILRRL 550 560 570 580 590 600 NAAEAFETFL QTKYVGQKRF SLEGGESVIP LLDAVIDSAA ESRLDEVVIG MAHRGRLNVL 610 620 630 640 650 660 ANVVGKSYAQ IFREFEGNLD PKSMHGSGDV KYHLGAEGTF TGLDGEQIKV SLVANPSHLE 670 680 690 700 710 720 AVDPVLEGVS RAKQDIINKG GTDFTVLPVA IHGDAAFAGQ GVVAETLNMS QLRGYRTGGT 730 740 750 760 770 780 VHVVINNQVG FTAAPESSRS SMYATDVARM IEAPIFHVNG DDPEAVVRVA RLAFEFRQAF 790 800 810 820 830 840 NKDVVIDLIC YRRRGHNETD NPAFTQPLMY DLIDKKRSVR KLYTESLIGR GDITLEEAEQ 850 860 870 880 890 900 ALQDYQGQLE KVFTEVREAV SQPASAEPSE PQAEFPVAVN TAITAETVKR IAESQVNIPD 910 920 930 940 950 960 HITVHPRLLP QLQRRAAMVE DGTIDWGMGE TLAVGSLLLD GVPVRLTGQD SQRGTFGQRH 970 980 990 1000 1010 1020 AVVIDRETGD EFTPLLYLSE DQARYNVYNS LLSEYAVMGF EYGYSLARPD ALVMWEAQFG 1030 1040 1050 1060 1070 1080 DFVNGAQTVV DEFISSAEQK WNQTSGVTLL LPHGYEGQGP DHSSARPERF LQLCAQNNMT 1090 1100 1110 1120 1130 1140 VAMPTLPSNY FHLLRWQVHN PHHKPLVVFT PKSMLRLKAA ASKAEEFTTG QFRPVIGDDS 1150 1160 1170 1180 1190 1200 VDPAAVKKVV FTAGKVYYDL DAERKKRGLT DTAIIRIERL YPLPGAELQA EIAKYPNAEK 1210 1220 1230 1240 1250 1260 YLWAQEEPAN QGAWPFIALN LIDHLDLAVG ADVPHGERLR RISRPHGSSP AVGSAKRHQA 1270 EQEQLVREVF EA

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939123 Genomic DNA. Translation: CAC04496.1.
RefSeq	NP_629426.1. NC_003888.3.
3D structure databases
HSSP	HSSP built from PDB template 1E2O based on UniProtKB P07016.
ProteinModelPortal	Q9FBR4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1100722.
GenomeReviews	Gene locus SCO5281 in contig AL645882_GR.
KEGG	sco:SCO5281.
NMPDR	fig|100226.1.peg.5236.
PATRIC	23740416. VBIStrCoe124346_5366.
Phylogenomic databases
HOGENOM	HBG289950.
OMA	EGDEPAF.
PhylomeDB	Q9FBR4.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9FBR4_STRCO

Accession

Primary (citable) accession number: Q9FBR4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)