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Q9FAB3 (SPKA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase A

EC=2.7.11.1
Gene names
Name:spkA
Ordered Locus Names:sll1574/sll1575
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length521 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Protein kinase that regulates cellular motility via phosphorylation of membrane proteins.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Post-translational modification

Autophosphorylated.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence caution

The sequence BAA17235.1 differs from that shown. Reason: Frameshift at position 103. sll1574 and sll1575 have been merged into one gene.

The sequence BAA17236.1 differs from that shown. Reason: Frameshift at position 103. sll1574 and sll1575 have been merged into one gene.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 521521Serine/threonine-protein kinase A
PRO_0000171239

Regions

Domain15 – 289275Protein kinase
Nucleotide binding21 – 299ATP By similarity

Sites

Active site1481Proton acceptor By similarity
Binding site451ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9FAB3 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 5FEC16F80D369C91

FASTA52158,875
        10         20         30         40         50         60 
MTPDSRHRRL LANRYQLVEL VGSGAMGQVY RAEDKLLGGV TVAVKFLSQA LLNPRMKERF 

        70         80         90        100        110        120 
EREATISALL GEKSIHIVRV RDYGLDEKEI PFYVMEYLQG ENISDVIKYR PLKVERFLKI 

       130        140        150        160        170        180 
ARQICFGLDC AHKGIIYQGE ACPVVHRDIK PSNVLLVEDP ALGELVKILD FGIAKLVQAA 

       190        200        210        220        230        240 
EESKTQAFMG TLAYCSPEQM EGKELDSRSD IYSLGVMMYE MLTGEMPLFP DNSSFGGWYE 

       250        260        270        280        290        300 
AHHHTKPHPF SARYKIPASL EALVMNCLAK SPKGRPQSVD VIIRAIDAIE AEIKAPPISD 

       310        320        330        340        350        360 
TEKTQIAPHL LNTDMEATVV AQRGPGIVPE TRLPLVSELC KQLEWPSDKP KQKIVFPYVL 

       370        380        390        400        410        420 
NAAEGKLASL WVMLNQEDIL TRMSSIRYNQ FLLMTSPHPM VLWITVLYHR EYGPRWLPCY 

       430        440        450        460        470        480 
LDLKTRSGQS FAQMLGESGT YWLLFFALEN PTRCQHMLTA TVAPNQCKLL KEWAQTSQSM 

       490        500        510        520 
PGGKPQVTKR LLKQELDRLK PKIEAKLSQV KPSFNKEVSG L 

« Hide

References

« Hide 'large scale' references
[1]"A eukaryotic-type protein kinase, SpkA, is required for normal motility of the unicellular Cyanobacterium synechocystis sp. strain PCC 6803."
Kamei A., Yuasa T., Orikawa K., Geng X.X., Ikeuchi M.
J. Bacteriol. 183:1505-1510(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB046597 Genomic DNA. Translation: BAB17033.1.
BA000022 Genomic DNA. Translation: BAA17235.1. Frameshift.
BA000022 Genomic DNA. Translation: BAA17236.1. Frameshift.
PIRS75321.
S75322.
RefSeqNP_440555.1. NC_000911.1.
NP_440556.1. NC_000911.1.
YP_005650613.1. NC_017277.1.
YP_005650614.1. NC_017277.1.
YP_007450439.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ9FAB3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9FAB3. 3 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17235; BAA17235; BAA17235.
BAA17236; BAA17236; BAA17236.
GeneID953856.
953857.
KEGGsyn:sll1574.
syn:sll1575.
syy:SYNGTS_0660.
syy:SYNGTS_0661.
syz:MYO_16670.
PATRIC23838296. VBISynSp132158_0715.

Phylogenomic databases

eggNOGCOG0515.
KOK08884.
OrthoDBEOG6B35XT.
PhylomeDBQ9FAB3.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPKA_SYNY3
AccessionPrimary (citable) accession number: Q9FAB3
Secondary accession number(s): P73208, P73209
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families