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Protein

Serine/threonine-protein kinase A

Gene

spkA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Protein kinase that regulates cellular motility via phosphorylation of membrane proteins.

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei45ATPPROSITE-ProRule annotation1
Active sitei148Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 29ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase A (EC:2.7.11.1)
Gene namesi
Name:spkA
Ordered Locus Names:sll1574/sll1575
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001712391 – 521Serine/threonine-protein kinase AAdd BLAST521

Post-translational modificationi

Autophosphorylated.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9FAB3
PRIDEiQ9FAB3

Interactioni

Protein-protein interaction databases

IntActiQ9FAB3, 3 interactors
STRINGi1148.SYNGTS_0660

Structurei

3D structure databases

ProteinModelPortaliQ9FAB3
SMRiQ9FAB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 289Protein kinasePROSITE-ProRule annotationAdd BLAST275

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiQ9FAB3
KOiK12132
PhylomeDBiQ9FAB3

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q9FAB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPDSRHRRL LANRYQLVEL VGSGAMGQVY RAEDKLLGGV TVAVKFLSQA
60 70 80 90 100
LLNPRMKERF EREATISALL GEKSIHIVRV RDYGLDEKEI PFYVMEYLQG
110 120 130 140 150
ENISDVIKYR PLKVERFLKI ARQICFGLDC AHKGIIYQGE ACPVVHRDIK
160 170 180 190 200
PSNVLLVEDP ALGELVKILD FGIAKLVQAA EESKTQAFMG TLAYCSPEQM
210 220 230 240 250
EGKELDSRSD IYSLGVMMYE MLTGEMPLFP DNSSFGGWYE AHHHTKPHPF
260 270 280 290 300
SARYKIPASL EALVMNCLAK SPKGRPQSVD VIIRAIDAIE AEIKAPPISD
310 320 330 340 350
TEKTQIAPHL LNTDMEATVV AQRGPGIVPE TRLPLVSELC KQLEWPSDKP
360 370 380 390 400
KQKIVFPYVL NAAEGKLASL WVMLNQEDIL TRMSSIRYNQ FLLMTSPHPM
410 420 430 440 450
VLWITVLYHR EYGPRWLPCY LDLKTRSGQS FAQMLGESGT YWLLFFALEN
460 470 480 490 500
PTRCQHMLTA TVAPNQCKLL KEWAQTSQSM PGGKPQVTKR LLKQELDRLK
510 520
PKIEAKLSQV KPSFNKEVSG L
Length:521
Mass (Da):58,875
Last modified:March 1, 2001 - v1
Checksum:i5FEC16F80D369C91
GO

Sequence cautioni

The sequence BAA17235 differs from that shown. Reason: Frameshift at position 103. sll1574 and sll1575 have been merged into one gene.Curated
The sequence BAA17236 differs from that shown. Reason: Frameshift at position 103. sll1574 and sll1575 have been merged into one gene.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046597 Genomic DNA Translation: BAB17033.1
BA000022 Genomic DNA Translation: BAA17235.1 Frameshift.
BA000022 Genomic DNA Translation: BAA17236.1 Frameshift.
PIRiS75321
S75322

Genome annotation databases

EnsemblBacteriaiBAA17235; BAA17235; BAA17235
BAA17236; BAA17236; BAA17236
KEGGisyn:sll1574
syn:sll1575

Similar proteinsi

Entry informationi

Entry nameiSPKA_SYNY3
AccessioniPrimary (citable) accession number: Q9FAB3
Secondary accession number(s): P73208, P73209
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

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