Unreviewed, UniProtKB/TrEMBL Q9F7K6 (Q9F7K6_SALCH)

Names and origin

Protein names

Recommended name:
    Glucose-1-phosphate thymidylyltransferase RuleBase RU003706V0
    EC=2.7.7.24

Gene names

Name:

rmlA EMBL AAG09500.1

Organism

Salmonella choleraesuis EMBL AAG09500.1

Taxonomic identifier

28901 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis By similarity. RuleBase RU003706V0
Catalytic activity	dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-glucose. RuleBase RU003706V0
Sequence similarities	Belongs to the glucose-1-phosphate thymidylyltransferase family. RuleBase RU003706V0

Ontologies

Keywords
Ligand	Magnesium RuleBase RU003706V0 Metal-binding RuleBase RU003706V0
Molecular function	Nucleotidyltransferase RuleBase RU003706V0 Transferase
Gene Ontology (GO)
Biological process	extracellular polysaccharide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	glucose-1-phosphate thymidylyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9F7K6-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: E1F74846DF0D1C34	FASTA	292	32,427
	10 20 30 40 50 60 MKTRKGIILA GGSGTRLYPV TMAVSKQLLP IYDKPMIYYP LSTLMLAGIR DILIISTPQD 70 80 90 100 110 120 TPRFQQLLGD GSQWGLNLQY KVQPSPDGLA QAFIIGEEFI GNDDCALVLG DNIFYGHDLP 130 140 150 160 170 180 KLMEAAVNKE SGATVFAYHV NDPERYGVVE FDQSGTAVSL EEKPLQPKSN YAVTGLYFYD 190 200 210 220 230 240 NSVVEMAKNL KPSARGELEI TDINRIYMDQ GRLSVAMMGR GYAWLDTGTH QSLIEASNFI 250 260 270 280 290 ATIEERQGLK VSCPEEIAYR KGFIDAEQIK NLAKPLSKNA YGQYLLNMIK GY

References

[1]	"Genetic variation of dTDP-L-rhamnose pathway genes in Salmonella enterica." Li Q., Reeves P.R. Microbiology 146:2291-2307(2000) [PubMed: 10974117] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization." Barton W.A., Lesniak J., Biggins J.B., Jeffrey P.D., Jiang J., Rajashankar K.R., Thorson J.S., Nikolov D.B. Nat. Struct. Biol. 8:545-551(2001) [PubMed: 11373625] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 1-291.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF279615 Genomic DNA. Translation: AAG09500.1.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR005907. G1P_thy_trans_l. IPR005835. NTP_transferase. [Graphical view]
Pfam	PF00483. NTP_transferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01207. rmlA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9F7K6_SALCH

Accession

Primary (citable) accession number: Q9F7K6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	May 5, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)