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Q9F7B2

- WZB_SALTY

UniProt

Q9F7B2 - WZB_SALTY

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Protein
Low molecular weight protein-tyrosine-phosphatase wzb
Gene
wzb, STM2117
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Dephosphorylates wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei9 – 91Nucleophile By similarity
Active sitei14 – 141 By similarity
Active sitei115 – 1151Proton donor By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. polysaccharide biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Exopolysaccharide synthesis

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2129-MONOMER.
UniPathwayiUPA00631.

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase wzb (EC:3.1.3.48)
Gene namesi
Name:wzb
Ordered Locus Names:STM2117
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 149149Low molecular weight protein-tyrosine-phosphatase wzb
PRO_0000046575Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi99287.STM2117.

Structurei

3D structure databases

ProteinModelPortaliQ9F7B2.
SMRiQ9F7B2. Positions 1-146.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0394.
HOGENOMiHOG000273091.
KOiK01104.
OMAiCELAPEM.
OrthoDBiEOG63VC26.
PhylomeDBiQ9F7B2.

Family and domain databases

InterProiIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717. PTHR11717. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9F7B2-1 [UniParc]FASTAAdd to Basket

« Hide

MFNKILVVCV GNVCRSPTAE RLLKRFHPSL TVASAGLGAL VGKGADPAAA    50
SVASAHDLSL ENHCARQISA RLCREYDLIL TMEKRHIAAL CDIAPEMRGK 100
VMLFGHWDSE REIPDPYRKS RDAFEAVYTL LERSARQWAQ ALNAEQGKP 149
Length:149
Mass (Da):16,474
Last modified:March 1, 2001 - v1
Checksum:iDA5DF9B5699EF208
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF285084 Genomic DNA. Translation: AAG24805.1.
AE006468 Genomic DNA. Translation: AAL21021.1.
RefSeqiNP_461062.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL21021; AAL21021; STM2117.
GeneIDi1253638.
KEGGistm:STM2117.
PATRICi32382817. VBISalEnt20916_2239.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF285084 Genomic DNA. Translation: AAG24805.1 .
AE006468 Genomic DNA. Translation: AAL21021.1 .
RefSeqi NP_461062.1. NC_003197.1.

3D structure databases

ProteinModelPortali Q9F7B2.
SMRi Q9F7B2. Positions 1-146.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 99287.STM2117.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL21021 ; AAL21021 ; STM2117 .
GeneIDi 1253638.
KEGGi stm:STM2117.
PATRICi 32382817. VBISalEnt20916_2239.

Phylogenomic databases

eggNOGi COG0394.
HOGENOMi HOG000273091.
KOi K01104.
OMAi CELAPEM.
OrthoDBi EOG63VC26.
PhylomeDBi Q9F7B2.

Enzyme and pathway databases

UniPathwayi UPA00631 .
BioCyci SENT99287:GCTI-2129-MONOMER.

Family and domain databases

InterProi IPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view ]
PANTHERi PTHR11717. PTHR11717. 1 hit.
Pfami PF01451. LMWPc. 1 hit.
[Graphical view ]
PRINTSi PR00719. LMWPTPASE.
SMARTi SM00226. LMWPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52788. SSF52788. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The colanic acid gene cluster of Salmonella enterica has a complex history."
    Stevenson G., Lan R., Reeves P.R.
    FEMS Microbiol. Lett. 191:11-16(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LT2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiWZB_SALTY
AccessioniPrimary (citable) accession number: Q9F7B2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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