Reviewed, UniProtKB/Swiss-Prot Q9F721 (CYB6_CHLTE)

Names and origin

Protein names

Recommended name:
    Cytochrome bc complex cytochrome b subunit

Gene names

Name:	petB
Ordered Locus Names:	CT0303

Organism

Chlorobium tepidum [Complete proteome] [HAMAP]

Taxonomic identifier

1097 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobaculum

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Component of the green S-bacteria bc complex, which consists of the Rieske protein and cytochrome b subunit but appears to lack a cytochrome c1-equivalent. This complex has a comparatively low redox potential By similarity.
Cofactor	Binds 2 heme groups non-covalently By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Miscellaneous	Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm By similarity.
Sequence similarities	Belongs to the cytochrome b family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Ligand	Heme Iron Metal-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	respiratory electron transport chain Inferred from electronic annotation. Source: InterPro transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 428	427	Cytochrome bc complex cytochrome b subunit		PRO_0000061917
Regions
	Transmembrane	108 – 128	21	Potential
	Transmembrane	160 – 180	21	Potential
	Transmembrane	191 – 211	21	Potential
	Transmembrane	258 – 278	21	Potential
	Transmembrane	310 – 329	20	Potential
	Transmembrane	367 – 387	21	Potential
	Transmembrane	399 – 419	21	Potential
Sites
	Metal binding	159	1	Iron 1 (heme b562 axial ligand) By similarity
	Metal binding	173	1	Iron 2 (heme b566 axial ligand) By similarity
	Metal binding	259	1	Iron 1 (heme b562 axial ligand) By similarity
	Metal binding	274	1	Iron 2 (heme b566 axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9F721-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: CA63747E6A132595	FASTA	428	47,495
	10 20 30 40 50 60 MAENTQNPAA GTAPAKPKPA VPGAAKPAAP GAAKPAAKAP AKPAAPAATA PSGVYKPPVD 70 80 90 100 110 120 RPDPNPFKDS KMSGVASWFQ ERFYVLNPII DYMKHKEVPK HRLSFWYYFG GLGLFFFIIQ 130 140 150 160 170 180 ILTGLLLLQY YKPTETDAFS SFLFIQGQVP FGWLIRQIHA WSANLMILML FIHMFSTFFM 190 200 210 220 230 240 KSYRKPRELL WVSGFILLVL TLGFGFTGYL LPWNELAFFA TQVGTEVPKV APGGAFLVEI 250 260 270 280 290 300 LRGGPDVSGE TLTRMFSLHV VLLPGLVMLV LAAHLTLVQV LGTSAPIGYK EAGLIKGYDK 310 320 330 340 350 360 FFPTFLAKDG IGWLIGFALL VYLAVMFPWE IGVKANPLSP APVGIKPEWY FWAQFQLLKD 370 380 390 400 410 420 FKFEGGELLA IILFTIGGVV WMLVPFLDRQ ASQEKKSPMF TIFGLLVLAF LLINTYRVYD SYVLHLPK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular evidence for the early evolution of photosynthesis." Xiong J., Fischer W.M., Inoue K., Nakahara M., Bauer C.E. Science 289:1724-1730(2000) [PubMed: 10976061] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 49652 / DSM 12025 / TLS.
[2]	"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium." Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M. , Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002) [PubMed: 12093901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49652 / DSM 12025 / TLS.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF287480 Genomic DNA. Translation: AAG12195.1. AE006470 Genomic DNA. Translation: AAM71549.1.
RefSeq	NP_661207.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1007963.
GenomeReviews	Gene locus CT0303 in contig AE006470_GR.
KEGG	cte:CT0303.
NMPDR	fig|194439.1.peg.301.
TIGR	CT0303.
Phylogenomic databases
HOGENOM	Q9F721.
OMA	Q9F721. QYYKPTE.
Enzyme and pathway databases
BioCyc	CTEP194439:CT_0303-MON.
Family and domain databases
InterPro	IPR016175. Cyt_b/b6. IPR005798. Cyt_b/b6_C. IPR005797. Cyt_b/b6_N. [Graphical view]
Gene3D	G3DSA:1.20.810.10. Cytochrome_b/b6. 1 hit.
PANTHER	PTHR19271. Cytochrome_b/b6. 1 hit.
Pfam	PF00033. Cytochrom_B_N. 1 hit. [Graphical view]
PROSITE	PS51003. CYTB_CTER. 1 hit. PS51002. CYTB_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYB6_CHLTE

Accession

Primary (citable) accession number: Q9F721

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
Last sequence update:	January 23, 2007
Last modified:	June 16, 2009
This is version 62 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)