Q9F664 (GALU_HAEDU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UTP--glucose-1-phosphate uridylyltransferase
EC=2.7.7.9

Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name=UDPGP
Uridine diphosphoglucose pyrophosphorylase

Gene names

Name:	galU
Ordered Locus Names:	HD_1431

Organism

Haemophilus ducreyi (strain 35000HP / ATCC 700724) [Complete proteome] [HAMAP]

Taxonomic identifier

233412 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus ducreyi

Protein attributes

Sequence length	295 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in stationary phase survival By similarity.
Catalytic activity	UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Sequence similarities	Belongs to the UDPGP type 2 family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	UDP-glucose metabolic process Inferred from electronic annotation. Source: InterPro biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 295	295	UTP--glucose-1-phosphate uridylyltransferase		PRO_0000201357

Sequences

	Sequence		Length	Mass (Da)
	Q9F664 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 025974C0752115CC	FASTA	295	32,518
	10 20 30 40 50 60 MKVIIPVAGL GTRMLPATKA IPKEMLTIAD KPLIQYIVNE CVAAGIKEIV FVTHSSKNAI 70 80 90 100 110 120 ENHFDTSFEL ETMLEKRVKR QLLDEVRSIV PNDVTLMHVR QGQAKGLGHA VLCGKAVVGK 130 140 150 160 170 180 EPFAVVLPDV ILADFTANPK TENLAAMIKR FSETQCSQIM VAPVPQEDVS NYGIVDCATD 190 200 210 220 230 240 NIRAGETAKI AKMVEKPSIE NAPSNLAIVG RYVFSATIWD LLERTPVGVG DEIQLTDAID 250 260 270 280 290 MLIEKETVEA FHMTGRAFDC GDKLGYMEAF VEYSLRHEKC GQQFQKIIKE LAKSL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Haemophilus ducreyi strain Hd9 strain produces a truncated lipooligosaccharide due to a mutation in UDP-glucose pyrophosphorylase (galU)." Sun S., Gibson B.W., Campagnari A.A., Munson R.S. Jr. Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The complete genome sequence of Haemophilus ducreyi." Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 35000HP / ATCC 700724.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF297520 Genomic DNA. Translation: AAG23691.1. AE017143 Genomic DNA. Translation: AAP96237.1.
RefSeq	NP_873848.1. NC_002940.2.
3D structure databases
ProteinModelPortal	Q9F664.
SMR	Q9F664. Positions 2-290.
ModBase	Search...
Protein-protein interaction databases
STRING	233412.HD1431.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAP96237; AAP96237; HD_1431.
GeneID	1491317.
KEGG	hdu:HD1431.
PATRIC	20179126. VBIHaeDuc133973_1197.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1210.
KO	K00963.
OMA	FIYFAQQ.
ProtClustDB	CLSK870436.
Enzyme and pathway databases
BioCyc	HDUC233412:GH5F-1248-MONOMER.
Family and domain databases
InterPro	IPR005771. GalU_uridylyltTrfase_bac/arc. IPR005835. NTP_transferase. [Graphical view]
Pfam	PF00483. NTP_transferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01099. galU. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GALU_HAEDU

Accession

Primary (citable) accession number: Q9F664

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	March 1, 2001
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program