Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene

galU

Organism
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May play a role in stationary phase survival.By similarity

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

GO - Molecular functioni

  1. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. biosynthetic process Source: InterPro
  2. UDP-glucose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Enzyme and pathway databases

BioCyciHDUC233412:GH5F-1295-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene namesi
Name:galU
Ordered Locus Names:HD_1431
OrganismiHaemophilus ducreyi (strain 35000HP / ATCC 700724)
Taxonomic identifieri233412 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000001022 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295UTP--glucose-1-phosphate uridylyltransferasePRO_0000201357Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi233412.HD1431.

Structurei

3D structure databases

ProteinModelPortaliQ9F664.
SMRiQ9F664. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.Curated

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiIETTIEF.
OrthoDBiEOG6Z9B3V.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01099. galU. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9F664-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVIIPVAGL GTRMLPATKA IPKEMLTIAD KPLIQYIVNE CVAAGIKEIV
60 70 80 90 100
FVTHSSKNAI ENHFDTSFEL ETMLEKRVKR QLLDEVRSIV PNDVTLMHVR
110 120 130 140 150
QGQAKGLGHA VLCGKAVVGK EPFAVVLPDV ILADFTANPK TENLAAMIKR
160 170 180 190 200
FSETQCSQIM VAPVPQEDVS NYGIVDCATD NIRAGETAKI AKMVEKPSIE
210 220 230 240 250
NAPSNLAIVG RYVFSATIWD LLERTPVGVG DEIQLTDAID MLIEKETVEA
260 270 280 290
FHMTGRAFDC GDKLGYMEAF VEYSLRHEKC GQQFQKIIKE LAKSL
Length:295
Mass (Da):32,518
Last modified:February 28, 2001 - v1
Checksum:i025974C0752115CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF297520 Genomic DNA. Translation: AAG23691.1.
AE017143 Genomic DNA. Translation: AAP96237.1.
RefSeqiNP_873848.1. NC_002940.2.
WP_010945286.1. NC_002940.2.

Genome annotation databases

EnsemblBacteriaiAAP96237; AAP96237; HD_1431.
KEGGihdu:HD1431.
PATRICi20179126. VBIHaeDuc133973_1197.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF297520 Genomic DNA. Translation: AAG23691.1.
AE017143 Genomic DNA. Translation: AAP96237.1.
RefSeqiNP_873848.1. NC_002940.2.
WP_010945286.1. NC_002940.2.

3D structure databases

ProteinModelPortaliQ9F664.
SMRiQ9F664. Positions 2-290.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi233412.HD1431.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP96237; AAP96237; HD_1431.
KEGGihdu:HD1431.
PATRICi20179126. VBIHaeDuc133973_1197.

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiIETTIEF.
OrthoDBiEOG6Z9B3V.

Enzyme and pathway databases

BioCyciHDUC233412:GH5F-1295-MONOMER.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005771. GalU_uridylyltTrfase_bac/arc.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01099. galU. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Haemophilus ducreyi strain Hd9 strain produces a truncated lipooligosaccharide due to a mutation in UDP-glucose pyrophosphorylase (galU)."
    Sun S., Gibson B.W., Campagnari A.A., Munson R.S. Jr.
    Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The complete genome sequence of Haemophilus ducreyi."
    Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L., Nguyen D., Wang J., Forst C., Hood L.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 35000HP / ATCC 700724.

Entry informationi

Entry nameiGALU_HAEDU
AccessioniPrimary (citable) accession number: Q9F664
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2003
Last sequence update: February 28, 2001
Last modified: March 31, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.