Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9F5P4 (DNAB_MYCIT) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Replicative DNA helicase

EC=3.6.4.12

Cleaved into the following chain:

  1. Min DnaB intein
Gene names
Name:dnaB
OrganismMycobacterium intracellulare
Taxonomic identifier1767 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)

Protein attributes

Sequence length576 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity By similarity.

Catalytic activity

ATP + H2O = ADP + phosphate.

Post-translational modification

This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation Potential.

Sequence similarities

Belongs to the helicase family. DnaB subfamily.

Contains 1 DOD-type homing endonuclease domain.

Contains 1 SF4 helicase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 15›15Replicative DNA helicase, 1st part Potential
PRO_0000013273
Chain16 – 351336Min DnaB intein Potential
PRO_0000013274
Chain352 – 576225Replicative DNA helicase, 2nd part Potential
PRO_0000013275

Regions

Domain154 – 260107DOD-type homing endonuclease
Domain313 – 576264SF4 helicase

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q9F5P4 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: 6D59341A779D082F

FASTA57663,530
        10         20         30         40         50         60 
RWADIIVAAR PGVGKALALD TPLPTPTGWT TTGDVAVGDE LLGADGKPTR VVAATEVLLG 

        70         80         90        100        110        120 
RPCYEVEFSD GTVIVADAAH QWLTETRASR KSAQAAAAGY NRYKNQRTFA AVRTTAEIAG 

       130        140        150        160        170        180 
TLRCPTLDRR LNHSVVNARA LDLPDREFLV PPYTLGAWLG DGTSAAAQIT AADPEIIMRI 

       190        200        210        220        230        240 
EAEMSSTVGT LQARLRTIGV LGNKHIPTEY LRGSETQRRE LLAGLLDTDG TVTAGGAVQF 

       250        260        270        280        290        300 
SVTNQRLACD VAELIVSLGY RCQTSTKRVR GRNESSSIAY TLTFSTEKKM FALERKAIHK 

       310        320        330        340        350        360 
ERRAMAGTTR SGSRFIVDVR PVETVAVRCV EVDNGSHLYL ASRAMVPTHN STLGLDFLRS 

       370        380        390        400        410        420 
CSIKHRMASV IFSLEMSKSE IVMRLLSAEA KIKLADMRSG RMSDEDWTRL ARRMSEISEA 

       430        440        450        460        470        480 
PLYIDDSPNL TMMEIRAKAR RLRQKADLRL VVVDYLQLMS SGKKVESRQL EVSEFSRQLK 

       490        500        510        520        530        540 
LLAKELEVPV VAISQLNRGP EQRTDKKPML SDLRESGSLE QDADMVILLN RPDAFERDDP 

       550        560        570 
RGGEADFILA KHRNGPTKTV TVAHQLHLSR FANMAR 

« Hide

References

[1]Madiraju M.V.V.S., Yamamoto K., Rajagopalan M., Rutherford S.A.
Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 1442.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF307984 Genomic DNA. Translation: AAG31144.1.

3D structure databases

ProteinModelPortalQ9F5P4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.170.16.10. 2 hits.
3.10.28.10. 2 hits.
3.40.50.300. 2 hits.
InterProIPR007694. DNA_helicase_DnaB-like_C.
IPR028992. Hedgehog/Intein_dom.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF03796. DnaB_C. 1 hit.
PF14528. LAGLIDADG_3. 1 hit.
[Graphical view]
PRINTSPR00379. INTEIN.
SUPFAMSSF51294. SSF51294. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55608. SSF55608. 1 hit.
PROSITEPS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS51199. SF4_HELICASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNAB_MYCIT
AccessionPrimary (citable) accession number: Q9F5P4
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Intein-containing proteins

List of intein-containing protein entries