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Q9F416

- RECA_MYCFA

UniProt

Q9F416 - RECA_MYCFA

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Protein

Protein RecA

Gene
recA
Organism
Mycobacterium fallax
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA-dependent ATPase activity Source: InterPro
  3. endonuclease activity Source: InterPro
  4. single-stranded DNA binding Source: InterPro

GO - Biological processi

  1. DNA recombination Source: UniProtKB-KW
  2. DNA repair Source: UniProtKB-KW
  3. intein-mediated protein splicing Source: InterPro
  4. SOS response Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecA
Alternative name(s):
Recombinase A
Cleaved into the following chain:
Gene namesi
Name:recA
OrganismiMycobacterium fallax
Taxonomic identifieri1793 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 9›9Protein RecA, 1st part Reviewed predictionPRO_0000030251
Chaini10 – 372363Mfa RecA intein Reviewed predictionPRO_0000030252Add
BLAST
Chaini373 – ›422›50Protein RecA, 2nd part Reviewed predictionPRO_0000030253Add
BLAST

Post-translational modificationi

This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation By similarity.

Keywords - PTMi

Autocatalytic cleavage, Protein splicing

Structurei

3D structure databases

ProteinModelPortaliQ9F416.
SMRiQ9F416. Positions 367-422.

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.

Family and domain databases

Gene3Di2.170.16.10. 2 hits.
3.10.28.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006141. Intein_splice_site.
IPR004860. LAGLIDADG_2.
IPR027417. P-loop_NTPase.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF03161. LAGLIDADG_2. 1 hit.
PF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF51294. SSF51294. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS50818. INTEIN_C_TER. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
PS00321. RECA_1. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9F416-1 [UniParc]FASTAAdd to Basket

« Hide

REKIGVMFGC FSYGTRVQLA DGSTEKIGKI VNQKMDVEVM SYDPVTDQIV    50
PRKVVNWFNN GPAEQFLQFT VEKSGGNGRS QFAATPNHLI RTPAGWTEAG 100
DLIAGDRVLA AERHLLSDQQ FQVILGSLMG GGNLSPNLHD RNGVRFRMGH 150
GARQADYLEW KTALLGNIGH SVRENDQGAR FVDFTPLPEL GELRRAVYLG 200
DGKKFLSEDY LKALTPLALA VWYMDDGSFT VRSKGVQQRT QGGSGRIEIC 250
VEAMAEGTRE RLRDYLRDTH GLDVRLRSAG SGKSMLTFST EATAKFQELV 300
APHMAPSMEH KLLPRFRGLG TVEPRFVEPA QRLVPARVLD VQVKPRTRSM 350
NRFDIEVEGN HNYFVDGVMV HNSPETTTGG KALKFYASVR MDVRRIETLK 400
DGSDAVGNRT RVKVVKNKVS PP 422
Length:422
Mass (Da):46,919
Last modified:March 1, 2001 - v1
Checksum:i90169C968BAAD209
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei422 – 4221

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ251337 Genomic DNA. Translation: CAC09589.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ251337 Genomic DNA. Translation: CAC09589.1 .

3D structure databases

ProteinModelPortali Q9F416.
SMRi Q9F416. Positions 367-422.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.170.16.10. 2 hits.
3.10.28.10. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006141. Intein_splice_site.
IPR004860. LAGLIDADG_2.
IPR027417. P-loop_NTPase.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view ]
PANTHERi PTHR22942:SF1. PTHR22942:SF1. 1 hit.
Pfami PF03161. LAGLIDADG_2. 1 hit.
PF00154. RecA. 1 hit.
[Graphical view ]
PRINTSi PR00142. RECA.
SMARTi SM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view ]
SUPFAMi SSF51294. SSF51294. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55608. SSF55608. 1 hit.
TIGRFAMsi TIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEi PS50818. INTEIN_C_TER. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
PS00321. RECA_1. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: CITP8139.

Entry informationi

Entry nameiRECA_MYCFA
AccessioniPrimary (citable) accession number: Q9F416
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: March 1, 2001
Last modified: June 11, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Intein-containing proteins
    List of intein-containing protein entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi