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Protein

Protein RecA

Gene

recA

Organism
Mycobacterium fallax
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecA
Alternative name(s):
Recombinase A
Cleaved into the following chain:
Gene namesi
Name:recA
OrganismiMycobacterium fallax
Taxonomic identifieri1793 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000030251‹1 – 9Protein RecA, 1st partSequence analysis›9
ChainiPRO_000003025210 – 372Mfa RecA inteinSequence analysisAdd BLAST363
ChainiPRO_0000030253373 – ›422Protein RecA, 2nd partSequence analysisAdd BLAST›50

Post-translational modificationi

This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation.By similarity

Keywords - PTMi

Autocatalytic cleavage, Protein splicing

Proteomic databases

PRIDEiQ9F416

Structurei

3D structure databases

ProteinModelPortaliQ9F416
SMRiQ9F416
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.Curated

Family and domain databases

Gene3Di3.10.28.10, 1 hit
InterProiView protein in InterPro
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR003586 Hint_dom_C
IPR003587 Hint_dom_N
IPR036844 Hint_dom_sf
IPR027434 Homing_endonucl
IPR030934 Intein_C
IPR006141 Intein_N
IPR004860 LAGLIDADG_2
IPR027417 P-loop_NTPase
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF03161 LAGLIDADG_2, 1 hit
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00305 HintC, 1 hit
SM00306 HintN, 1 hit
SUPFAMiSSF51294 SSF51294, 2 hits
SSF52540 SSF52540, 1 hit
SSF55608 SSF55608, 1 hit
TIGRFAMsiTIGR01443 intein_Cterm, 1 hit
TIGR01445 intein_Nterm, 1 hit
PROSITEiView protein in PROSITE
PS50818 INTEIN_C_TER, 1 hit
PS50817 INTEIN_N_TER, 1 hit
PS00321 RECA_1, 1 hit
PS50163 RECA_3, 1 hit

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9F416-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
REKIGVMFGC FSYGTRVQLA DGSTEKIGKI VNQKMDVEVM SYDPVTDQIV
60 70 80 90 100
PRKVVNWFNN GPAEQFLQFT VEKSGGNGRS QFAATPNHLI RTPAGWTEAG
110 120 130 140 150
DLIAGDRVLA AERHLLSDQQ FQVILGSLMG GGNLSPNLHD RNGVRFRMGH
160 170 180 190 200
GARQADYLEW KTALLGNIGH SVRENDQGAR FVDFTPLPEL GELRRAVYLG
210 220 230 240 250
DGKKFLSEDY LKALTPLALA VWYMDDGSFT VRSKGVQQRT QGGSGRIEIC
260 270 280 290 300
VEAMAEGTRE RLRDYLRDTH GLDVRLRSAG SGKSMLTFST EATAKFQELV
310 320 330 340 350
APHMAPSMEH KLLPRFRGLG TVEPRFVEPA QRLVPARVLD VQVKPRTRSM
360 370 380 390 400
NRFDIEVEGN HNYFVDGVMV HNSPETTTGG KALKFYASVR MDVRRIETLK
410 420
DGSDAVGNRT RVKVVKNKVS PP
Length:422
Mass (Da):46,919
Last modified:March 1, 2001 - v1
Checksum:i90169C968BAAD209
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei4221

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ251337 Genomic DNA Translation: CAC09589.1

Similar proteinsi

Entry informationi

Entry nameiRECA_MYCFA
AccessioniPrimary (citable) accession number: Q9F416
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Intein-containing proteins
    List of intein-containing protein entries
  2. SIMILARITY comments
    Index of protein domains and families

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