Q9F416 (RECA_MYCFA) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 73.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Protein RecA Alternative name(s): Recombinase A Cleaved into the following chain: | ||
| Gene names |
| ||
| Organism | Mycobacterium fallax | ||
| Taxonomic identifier | 1793 [NCBI] | ||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium![]() |
Protein attributes
| Sequence length | 422 AA. |
| Sequence status | Fragment. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity. HAMAP-Rule MF_00268 |
| Subcellular location | Cytoplasm By similarity. |
| Post-translational modification | This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation By similarity. HAMAP-Rule MF_00268 |
| Sequence similarities | Belongs to the RecA family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | DNA damage DNA recombination DNA repair SOS response |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding DNA-binding Nucleotide-binding |
| PTM | Autocatalytic cleavage Protein splicing |
| Gene Ontology (GO) | |
| Biological_process | DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA repairInferred from electronic annotation. Source: UniProtKB-KW SOS responseInferred from electronic annotation. Source: UniProtKB-KW intein-mediated protein splicingInferred from electronic annotation. Source: InterPro |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA-dependent ATPase activityInferred from electronic annotation. Source: InterPro endonuclease activityInferred from electronic annotation. Source: InterPro single-stranded DNA bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | ‹1 – 9 | ›9 | Protein RecA, 1st part Potential | PRO_0000030251 | |||||
| Chain | 10 – 372 | 363 | Mfa RecA intein Potential | PRO_0000030252 | |||||
| Chain | 373 – ›422 | ›50 | Protein RecA, 2nd part Potential | PRO_0000030253 | |||||
Experimental info | |||||||||
| Non-terminal residue | 1 | 1 | |||||||
| Non-terminal residue | 422 | 1 | |||||||
Sequences
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References
| [1] | "Inteins invading mycobacterial RecA proteins." Saves I., Laneelle M.-A., Daffe M., Masson J.-M. FEBS Lett. 480:221-225(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CITP8139. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AJ251337 Genomic DNA. Translation: CAC09589.1. |
3D structure databases | |
| ProteinModelPortal | Q9F416. |
| SMR | Q9F416. Positions 367-422. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| HAMAP | MF_00268. RecA. |
| InterPro | IPR013765. DNA_recomb/repair_RecA. IPR020584. DNA_recomb/repair_RecA_CS. IPR003586. Hint_dom_C. IPR003587. Hint_dom_N. IPR006141. Intein_splice_site. IPR004860. LAGLIDADG_2. IPR020587. RecA_monomer-monomer_interface. [Graphical view] |
| PANTHER | PTHR22942:SF1. PTHR22942:SF1. 1 hit. |
| Pfam | PF03161. LAGLIDADG_2. 1 hit. PF00154. RecA. 1 hit. [Graphical view] |
| PRINTS | PR00142. RECA. |
| SMART | SM00305. HintC. 1 hit. SM00306. HintN. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01443. intein_Cterm. 1 hit. TIGR01445. intein_Nterm. 1 hit. |
| PROSITE | PS50818. INTEIN_C_TER. 1 hit. PS50817. INTEIN_N_TER. 1 hit. PS00321. RECA_1. 1 hit. PS50162. RECA_2. False negative. PS50163. RECA_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RECA_MYCFA | ||||||||
| Accession | Primary (citable) accession number: Q9F416 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Intein-containing proteins List of intein-containing protein entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with
