Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9F411

- TRMB_MYCHP

UniProt

Q9F411 - TRMB_MYCHP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Mycoplasma hominis (strain ATCC 23114 / NBRC 14850 / NCTC 10111 / PG21)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei34 – 341S-adenosyl-L-methionineUniRule annotation
Binding sitei59 – 591S-adenosyl-L-methionineUniRule annotation
Binding sitei86 – 861S-adenosyl-L-methionineUniRule annotation
Active sitei107 – 1071By similarity
Binding sitei107 – 1071S-adenosyl-L-methionineUniRule annotation
Binding sitei111 – 1111SubstrateUniRule annotation
Binding sitei143 – 1431SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMHOM347256:GBZD-466-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:MHO_4250
OrganismiMycoplasma hominis (strain ATCC 23114 / NBRC 14850 / NCTC 10111 / PG21)
Taxonomic identifieri347256 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000002631: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202tRNA (guanine-N(7)-)-methyltransferasePRO_0000171352Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi2098.MHO_4250.

Structurei

3D structure databases

ProteinModelPortaliQ9F411.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni181 – 1844Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000251689.
KOiK03439.
OMAiGCGKGEY.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9F411-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLRFNKNAE TSLMASPMTF KDFPIDNKKN TILEIGMGRG TMLTKLALMH
60 70 80 90 100
PDIEYIGLEK YSTPAYSALK KAIDLNLENF HIIIGDAINL STYFKNKIKT
110 120 130 140 150
IWLTFSDPWP KKRHYKRRLV YRDFLKIYQN VLDKDGVVYF KTDNDMLYQF
160 170 180 190 200
AIDELKEINA KIIYQTSDLH HCNFKIENVF TDYEEKFNKL NKNINFIAFT

FN
Length:202
Mass (Da):23,951
Last modified:March 1, 2001 - v1
Checksum:iD8993C44B381BB0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U59880 Genomic DNA. Translation: AAG28841.1.
FP236530 Genomic DNA. Translation: CAX37560.1.
RefSeqiWP_012855699.1. NC_013511.1.
YP_003302963.1. NC_013511.1.

Genome annotation databases

EnsemblBacteriaiCAX37560; CAX37560; MHO_4250.
GeneIDi8595146.
KEGGimho:MHO_4250.
PATRICi32274019. VBIMycHom120329_0443.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U59880 Genomic DNA. Translation: AAG28841.1 .
FP236530 Genomic DNA. Translation: CAX37560.1 .
RefSeqi WP_012855699.1. NC_013511.1.
YP_003302963.1. NC_013511.1.

3D structure databases

ProteinModelPortali Q9F411.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 2098.MHO_4250.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAX37560 ; CAX37560 ; MHO_4250 .
GeneIDi 8595146.
KEGGi mho:MHO_4250.
PATRICi 32274019. VBIMycHom120329_0443.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000251689.
KOi K03439.
OMAi GCGKGEY.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci MHOM347256:GBZD-466-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and nucleotide sequence of the DNA gyrase (gyrA) gene from Mycoplasma hominis and characterization of quinolone-resistant mutants selected In vitro with trovafloxacin."
    Bebear C.M., Grau O., Charron A., Renaudin H., Gruson D., Bebear C.
    Antimicrob. Agents Chemother. 44:2719-2727(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Life on arginine for Mycoplasma hominis: clues from its minimal genome and comparison with other human urogenital mycoplasmas."
    Pereyre S., Sirand-Pugnet P., Beven L., Charron A., Renaudin H., Barre A., Avenaud P., Jacob D., Couloux A., Barbe V., de Daruvar A., Blanchard A., Bebear C.
    PLoS Genet. 5:E1000677-E1000677(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23114 / NBRC 14850 / NCTC 10111 / PG21.

Entry informationi

Entry nameiTRMB_MYCHP
AccessioniPrimary (citable) accession number: Q9F411
Secondary accession number(s): D1J8L3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: March 1, 2001
Last modified: October 1, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3