Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase [Mn/Fe]

Gene

sodA

Organism
Staphylococcus carnosus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.1 Publication

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarity, Fe2+By similarityNote: Binds 1 Mn2+ or Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27Manganese or ironBy similarity1
Metal bindingi81Manganese or ironBy similarity1
Metal bindingi162Manganese or ironBy similarity1
Metal bindingi166Manganese or ironBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Stress response

Keywords - Ligandi

Iron, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
Gene namesi
Name:sodA
Synonyms:sod
OrganismiStaphylococcus carnosus
Taxonomic identifieri1281 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002939681 – 201Superoxide dismutase [Mn/Fe]Add BLAST201

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi396513.Sca_1174.

Structurei

3D structure databases

ProteinModelPortaliQ9F326.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4. Bacteria.
COG0605. LUCA.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9F326-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFELPNLPY EFDALEPYID KETMEIHHDK HHNTYVTKLN AAIEGTDLEN
60 70 80 90 100
KSIEEIVANL DSVPSDIQTA VRNNGGGHLN HSLFWQLLTP NSEEKGTVID
110 120 130 140 150
KIKEEWGSLD KFKDEFAKKA AGQFGSGWAW LVVDKDGKLE IVSTPNQDNP
160 170 180 190 200
ITEGKTPILG LDVWEHAYYL KYQNKRPDYI DAFWNVVNWN KVDELYEAAT

K
Length:201
Mass (Da):22,980
Last modified:March 1, 2001 - v1
Checksum:i4F23EF7BF19556A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ295150 Genomic DNA. Translation: CAC14833.1.
AY795886 Genomic DNA. Translation: AAW32466.1.
RefSeqiWP_015900423.1. NZ_LISV01000002.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ295150 Genomic DNA. Translation: CAC14833.1.
AY795886 Genomic DNA. Translation: AAW32466.1.
RefSeqiWP_015900423.1. NZ_LISV01000002.1.

3D structure databases

ProteinModelPortaliQ9F326.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi396513.Sca_1174.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105CK4. Bacteria.
COG0605. LUCA.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSODM_STACA
AccessioniPrimary (citable) accession number: Q9F326
Secondary accession number(s): Q5IBS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: March 1, 2001
Last modified: October 5, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

SOD activity increases in mid-exponential growth-phase.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.