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Protein

Superoxide dismutase [Mn/Fe]

Gene

sodA

Organism
Staphylococcus carnosus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.1 Publication

Miscellaneous

SOD activity increases in mid-exponential growth-phase.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarity, Fe2+By similarityNote: Binds 1 Mn2+ or Fe2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27Manganese or ironBy similarity1
Metal bindingi81Manganese or ironBy similarity1
Metal bindingi162Manganese or ironBy similarity1
Metal bindingi166Manganese or ironBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processStress response
LigandIron, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
Gene namesi
Name:sodA
Synonyms:sod
OrganismiStaphylococcus carnosus
Taxonomic identifieri1281 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002939681 – 201Superoxide dismutase [Mn/Fe]Add BLAST201

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9F326
SMRiQ9F326
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4 Bacteria
COG0605 LUCA

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Q9F326-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFELPNLPY EFDALEPYID KETMEIHHDK HHNTYVTKLN AAIEGTDLEN
60 70 80 90 100
KSIEEIVANL DSVPSDIQTA VRNNGGGHLN HSLFWQLLTP NSEEKGTVID
110 120 130 140 150
KIKEEWGSLD KFKDEFAKKA AGQFGSGWAW LVVDKDGKLE IVSTPNQDNP
160 170 180 190 200
ITEGKTPILG LDVWEHAYYL KYQNKRPDYI DAFWNVVNWN KVDELYEAAT

K
Length:201
Mass (Da):22,980
Last modified:March 1, 2001 - v1
Checksum:i4F23EF7BF19556A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ295150 Genomic DNA Translation: CAC14833.1
AY795886 Genomic DNA Translation: AAW32466.1
RefSeqiWP_015900423.1, NZ_LISV01000002.1

Genome annotation databases

PATRICifig|1281.6.peg.252

Similar proteinsi

Entry informationi

Entry nameiSODM_STACA
AccessioniPrimary (citable) accession number: Q9F326
Secondary accession number(s): Q5IBS1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health