Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-lactamase

Gene

blaUOE-1

Organism
Escherichia coli
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processAntibiotic resistanceUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS11.A01.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseUniRule annotationSAAS annotation (EC:3.5.2.6UniRule annotationSAAS annotation)
Gene namesi
Name:blaUOE-1Imported
Synonyms:blaImported, bla CTX-M-15Imported, bla_2Imported, blaCTX-M-15Imported, blaCTX-M15Imported, CTX-M-15Imported
ORF Names:AM341_25235Imported, B1K96_05075Imported, BMR28_12470Imported, CA268_09065Imported, CA268_27315Imported, CDN87_08160Imported, CI718_17535Imported, CRM83_00400Imported, CSB65_19565Imported, ECONIH1_02760Imported, ECONIH1_27135Imported, MS6198_B109Imported
Encoded oniPlasmid IncF::A/CImported
Plasmid IncF::IncL/MImported
Plasmid p1002-1Imported
Plasmid p25104Imported
Plasmid pBP971-95Imported
Plasmid pC15-1aImported
Plasmid pCTX1929Imported
Plasmid pCTX913Imported
Plasmid pECO-824Imported
Plasmid pEK516Imported
Plasmid pESBL-12Imported
Plasmid pHNY2Imported
Plasmid pJIE098Imported
Plasmid pJIE100Imported
Plasmid pJIE101Imported
Plasmid pJIE118Imported
Plasmid pJIE134Imported
Plasmid pJIE143Imported
Plasmid pJIE186Imported
Plasmid pJIE250Imported
Plasmid pJIE286Imported
Plasmid pKC390Imported
Plasmid pKC404Imported
Plasmid pKC405Imported
Plasmid pKCT407Imported
Plasmid pMS6198BImported
Plasmid pMTE001Imported
Plasmid pYC-14Imported
Plasmid pYC-5bImported
Plasmid pblaCTX-M-11Imported
Plasmid pms6198bImported
Plasmid unitig_1_pilonImported
Plasmid unnamedImported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000230960 Componenti: Plasmid unitig_1_pilon
  • UP000225895 Componenti: Unassembled WGS sequence
  • UP000222575 Componenti: Unassembled WGS sequence
  • UP000220282 Componenti: Unassembled WGS sequence
  • UP000094504 Componenti: Plasmid pms6198b
  • UP000194331 Componenti: Plasmid p1002-1
  • UP000194285 Componenti: Unassembled WGS sequence
  • UP000030317 Componenti: Plasmid pECO-824
  • UP000215981 Componenti: Unassembled WGS sequence
  • UP000215519 Componenti: Unassembled WGS sequence

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL6131.
DrugBankiDB09060. Avibactam.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501410803629 – 291Beta-lactamaseSequence analysisAdd BLAST263

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4HBTX-ray1.10A29-291[»]
4HBUX-ray1.10A29-291[»]
5FA7X-ray1.67A/B26-291[»]
5FAOX-ray3.01A/B29-291[»]
5FAPX-ray2.70A/B29-291[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK18767.
OMAiAMCSTSK.

Family and domain databases

InterProiView protein in InterPro
IPR012338. Beta-lactam/transpept-like.
IPR000871. Beta-lactam_class-A.
IPR023650. Beta-lactam_class-A_AS.
PRINTSiPR00118. BLACTAMASEA.
SUPFAMiSSF56601. SSF56601. 1 hit.
PROSITEiView protein in PROSITE
PS00146. BETA_LACTAMASE_A. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9EXV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKKSLRQFT LMATATVTLL LGSVPLYAQT ADVQQKLAEL ERQSGGRLGV
60 70 80 90 100
ALINTADNSQ ILYRADERFA MCSTSKVMAA AAVLKKSESE PNLLNQRVEI
110 120 130 140 150
KKSDLVNYNP IAEKHVNGTM SLAELSAAAL QYSDNVAMNK LIAHVGGPAS
160 170 180 190 200
VTAFARQLGD ETFRLDRTEP TLNTAIPGDP RDTTSPRAMA QTLRNLTLGK
210 220 230 240 250
ALGDSQRAQL VTWMKGNTTG AASIQAGLPA SWVVGDKTGS GGYGTTNDIA
260 270 280 290
VIWPKDRAPL ILVTYFTQPQ PKAESRRDVL ASAAKIVTDG L
Length:291
Mass (Da):31,144
Last modified:March 1, 2001 - v1
Checksum:i49C531A7D5607BA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY013478 Genomic DNA. Translation: AAG48377.1.
AY044436 Genomic DNA. Translation: AAL02127.1.
AY458016 Genomic DNA. Translation: AAR25032.1.
AY462238 Genomic DNA. Translation: AAR26004.1.
AY463958 Genomic DNA. Translation: AAR28032.1.
AY604721 Genomic DNA. Translation: AAT48020.1.
AY604722 Genomic DNA. Translation: AAT48025.1.
AY960984 Genomic DNA. Translation: AAY27811.1.
DQ335219 Genomic DNA. Translation: ABC73077.1.
DQ485310 Genomic DNA. Translation: ABE76830.1.
DQ915953 Genomic DNA. Translation: ABK06381.1.
EU350510 Genomic DNA. Translation: ABY66122.1.
EU418920 Genomic DNA. Translation: ACN58169.1.
EU935738 Genomic DNA. Translation: ACQ41904.1.
GQ330540 Genomic DNA. Translation: ACT85952.1.
GQ274928 Genomic DNA. Translation: ACV32734.1.
GQ274932 Genomic DNA. Translation: ACV32752.1.
GQ274933 Genomic DNA. Translation: ACV32754.1.
GQ274935 Genomic DNA. Translation: ACV32764.1.
GQ385309 Genomic DNA. Translation: ACX54236.1.
HQ157353 Genomic DNA. Translation: ADO16967.1.
HQ157354 Genomic DNA. Translation: ADO16970.1.
HQ157355 Genomic DNA. Translation: ADO16973.1.
HQ157356 Genomic DNA. Translation: ADO16976.1.
HQ157357 Genomic DNA. Translation: ADO16979.1.
JN194214 Genomic DNA. Translation: AEQ61756.1.
EU418932 Genomic DNA. Translation: AER36578.1.
GU264003 Genomic DNA. Translation: AER36586.1.
EU418921 Genomic DNA. Translation: AER36589.1.
EU418922 Genomic DNA. Translation: AER36602.1.
EU418924 Genomic DNA. Translation: AER36618.1.
EU418925 Genomic DNA. Translation: AER36624.1.
EU418930 Genomic DNA. Translation: AER36626.1.
JQ318855 Genomic DNA. Translation: AFH01005.1.
JQ397655 Genomic DNA. Translation: AFI26281.1.
JQ397656 Genomic DNA. Translation: AFI26284.1.
JQ397658 Genomic DNA. Translation: AFI26289.1.
JQ397659 Genomic DNA. Translation: AFI26292.1.
JQ397660 Genomic DNA. Translation: AFI26295.1.
JQ397661 Genomic DNA. Translation: AFI26298.1.
JQ397662 Genomic DNA. Translation: AFI26301.1.
JQ397663 Genomic DNA. Translation: AFI26304.1.
JQ397667 Genomic DNA. Translation: AFI26314.1.
JX129216 Genomic DNA. Translation: AFQ20795.1.
JX129217 Genomic DNA. Translation: AFQ20796.1.
JX129218 Genomic DNA. Translation: AFQ20797.1.
JX129221 Genomic DNA. Translation: AFQ20800.1.
JX129222 Genomic DNA. Translation: AFQ20801.1.
KC817478 Genomic DNA. Translation: AGR34004.1.
KF155154 Genomic DNA. Translation: AGY62865.1.
KF155155 Genomic DNA. Translation: AGY62869.1.
KF155155 Genomic DNA. Translation: AGY62870.1.
KF155157 Genomic DNA. Translation: AGY62877.1.
KF155158 Genomic DNA. Translation: AGY62880.1.
KF155159 Genomic DNA. Translation: AGY62884.1.
KF155160 Genomic DNA. Translation: AGY62889.1.
KF155161 Genomic DNA. Translation: AGY62895.1.
KF601686 Genomic DNA. Translation: AGZ85192.1.
KJ533731 Genomic DNA. Translation: AHZ64975.1.
KJ533732 Genomic DNA. Translation: AHZ64976.1.
KJ533733 Genomic DNA. Translation: AHZ64977.1.
KJ533734 Genomic DNA. Translation: AHZ64978.1.
KJ533735 Genomic DNA. Translation: AHZ64979.1.
KJ533736 Genomic DNA. Translation: AHZ64980.1.
KJ533737 Genomic DNA. Translation: AHZ64981.1.
KJ533738 Genomic DNA. Translation: AHZ64982.1.
KJ533739 Genomic DNA. Translation: AHZ64983.1.
KJ533740 Genomic DNA. Translation: AHZ64984.1.
CP008735 Genomic DNA. Translation: AIG72475.1.
KF891471 Genomic DNA. Translation: AIJ28670.1.
CP009859 Genomic DNA. Translation: AIX62232.1.
CP009860 Genomic DNA. Translation: AIX66880.1.
CP015836 Genomic DNA. Translation: AOM73348.1.
CP021202 Genomic DNA. Translation: ARR59549.1.
CP021203 Genomic DNA. Translation: ARR63004.1.
CP024860 Genomic DNA. Translation: ATX54967.1.
AB683462 Genomic DNA. Translation: BAM15698.1.
AB683463 Genomic DNA. Translation: BAM15702.1.
AB683464 Genomic DNA. Translation: BAM15704.1.
AB683465 Genomic DNA. Translation: BAM15706.1.
AB701567 Genomic DNA. Translation: BAM38180.1.
AB701568 Genomic DNA. Translation: BAM38185.1.
AB701569 Genomic DNA. Translation: BAM38189.1.
AB701570 Genomic DNA. Translation: BAM38193.1.
AB701571 Genomic DNA. Translation: BAM38196.1.
AB701572 Genomic DNA. Translation: BAM38201.1.
AB701573 Genomic DNA. Translation: BAM38205.1.
AB976566 Genomic DNA. Translation: BAP18770.1.
AB976569 Genomic DNA. Translation: BAP18779.1.
AB976570 Genomic DNA. Translation: BAP18782.1.
AB976574 Genomic DNA. Translation: BAP18795.1.
AB976575 Genomic DNA. Translation: BAP18799.1.
AB976576 Genomic DNA. Translation: BAP18801.1.
AB976579 Genomic DNA. Translation: BAP18811.1.
AJ310929 Genomic DNA. Translation: CAC84572.1.
AM040706 Genomic DNA. Translation: CAJ13638.1.
FR828676 Genomic DNA. Translation: CCA28537.1.
HF549093 Genomic DNA. Translation: CCO61930.1.
HG798331 Genomic DNA. Translation: CDL67816.1.
NBCM01000004 Genomic DNA. Translation: OTE94265.1.
NQDM01000079 Genomic DNA. Translation: OYK38027.1.
NJAF01000020 Genomic DNA. Translation: PAS70685.1.
PDEE01000001 Genomic DNA. Translation: PEI02095.1.
MPIJ01000016 Genomic DNA. Translation: PGG22362.1.
PEDR01000039 Genomic DNA. Translation: PHW94480.1.
RefSeqiNP_957562.1. NC_005327.1.
WP_000239590.1. NZ_PJDC01000012.1.
YP_003108206.1. NC_013121.1.
YP_009061308.1. NC_024977.1.

Genome annotation databases

EnsemblBacteriaiAIX62232; AIX62232; ECONIH1_02760.
AIX66880; AIX66880; ECONIH1_27135.
AOM73348; AOM73348; MS6198_B109.
ODA89280; ODA89280; A9D65_00020.
ODH15859; ODH15859; A6804_26620.
ODH25949; ODH25949; A6803_25395.
GeneIDi20468332.
2716485.
35548257.
8319161.
KEGGiag:AAL02127.
PATRICifig|562.10474.peg.5733.

Similar proteinsi

Entry informationi

Entry nameiQ9EXV5_ECOLX
AccessioniPrimary (citable) accession number: Q9EXV5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported, PlasmidImported