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Q9EWP1

- Q9EWP1_STRCO

UniProt

Q9EWP1 - Q9EWP1_STRCO

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Protein
Submitted name:

Putative cytochrome P450

Gene

SCO7686

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi360 – 3601Iron (heme axial ligand)Imported

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. monooxygenase activity Source: UniProtKB-KW
  4. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotationSAAS annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotationSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative cytochrome P450Imported
Gene namesi
Ordered Locus Names:SCO7686Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO7686.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TYWX-ray2.90A/B/C/D1-411[»]
4FXBX-ray2.90A/B1-411[»]
ProteinModelPortaliQ9EWP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000243678.
InParanoidiQ9EWP1.
OMAiTHNGRRR.
OrthoDBiEOG6JB11P.
PhylomeDBiQ9EWP1.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00359. BP450.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9EWP1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPPESPTAS HTPGATPPRD FPIQRGCPFA APAEYAALRT DDPVARVTLP
60 70 80 90 100
TRREAWVVTR YDDVRELLSD PRVSADIRRP GFPALGEGEQ EAGARFRPFI
110 120 130 140 150
RTDAPEHTRY RRMLLPAFTV RRVRAMRPAV QARVDEILDG MLAAGGPVDL
160 170 180 190 200
VSAYANAVST SVICELLGIP RHDLEFFRDV TRISGSRNST AEQVSEALGG
210 220 230 240 250
LFGLLGGLVA ERREEPRDDL ISKLVTDHLV PGNVTTEQLL STLGITINAG
260 270 280 290 300
RETTTSMIAL STLLLLDRPE LPAELRKDPD LMPAAVDELL RVLSVADSIP
310 320 330 340 350
LRVAAEDIEL SGRTVPADDG VIALLAGANH DPEQFDDPER VDFHRTDNHH
360 370 380 390 400
VAFGYGVHQC VGQHLARLEL EVALETLLRR VPTLRLAGER DQVVVKHDSA
410
TFGLEELMVT W
Length:411
Mass (Da):45,100
Last modified:March 1, 2001 - v1
Checksum:i7E6F07608BC09B5D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939132 Genomic DNA. Translation: CAC17503.1.
RefSeqiNP_631725.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAC17503; CAC17503; CAC17503.
GeneIDi1103124.
KEGGisco:SCO7686.
PATRICi23745329. VBIStrCoe124346_7807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939132 Genomic DNA. Translation: CAC17503.1 .
RefSeqi NP_631725.1. NC_003888.3.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3TYW X-ray 2.90 A/B/C/D 1-411 [» ]
4FXB X-ray 2.90 A/B 1-411 [» ]
ProteinModelPortali Q9EWP1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO7686.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC17503 ; CAC17503 ; CAC17503 .
GeneIDi 1103124.
KEGGi sco:SCO7686.
PATRICi 23745329. VBIStrCoe124346_7807.

Phylogenomic databases

HOGENOMi HOG000243678.
InParanoidi Q9EWP1.
OMAi THNGRRR.
OrthoDBi EOG6JB11P.
PhylomeDBi Q9EWP1.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
PRINTSi PR00359. BP450.
PR00385. P450.
SUPFAMi SSF48264. SSF48264. 1 hit.
PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145Imported.
  2. "Crystal Structure of CYP105N1 from Streptomyces coelicolor A3(2)."
    Zhao B., Waterman M.R.
    Submitted (SEP-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME.
  3. "Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway."
    Lim Y.R., Hong M.K., Kim J.K., Doan T.T., Kim D.H., Yun C.H., Chun Y.J., Kang L.W., Kim D.
    Arch. Biochem. Biophys. 528:111-117(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME.

Entry informationi

Entry nameiQ9EWP1_STRCO
AccessioniPrimary (citable) accession number: Q9EWP1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3