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Q9EWP1

- Q9EWP1_STRCO

UniProt

Q9EWP1 - Q9EWP1_STRCO

Protein
Submitted name:

Putative cytochrome P450

Gene

SCO7686

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Mar 2001)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi360 – 3601Iron (heme axial ligand)Imported

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. monooxygenase activity Source: UniProtKB-KW
    4. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro

    Keywords - Molecular functioni

    MonooxygenaseUniRule annotationSAAS annotation, Oxidoreductase

    Keywords - Ligandi

    HemeUniRule annotationSAAS annotationImported, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative cytochrome P450Imported
    Gene namesi
    Ordered Locus Names:SCO7686Imported
    OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
    Taxonomic identifieri100226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
    ProteomesiUP000001973: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi100226.SCO7686.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3TYWX-ray2.90A/B/C/D1-411[»]
    4FXBX-ray2.90A/B1-411[»]
    ProteinModelPortaliQ9EWP1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome P450 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000243678.
    OMAiTHNGRRR.
    OrthoDBiEOG6JB11P.
    PhylomeDBiQ9EWP1.

    Family and domain databases

    Gene3Di1.10.630.10. 1 hit.
    InterProiIPR001128. Cyt_P450.
    IPR002397. Cyt_P450_B.
    IPR017972. Cyt_P450_CS.
    [Graphical view]
    PfamiPF00067. p450. 1 hit.
    [Graphical view]
    PRINTSiPR00359. BP450.
    PR00385. P450.
    SUPFAMiSSF48264. SSF48264. 1 hit.
    PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9EWP1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTPPESPTAS HTPGATPPRD FPIQRGCPFA APAEYAALRT DDPVARVTLP    50
    TRREAWVVTR YDDVRELLSD PRVSADIRRP GFPALGEGEQ EAGARFRPFI 100
    RTDAPEHTRY RRMLLPAFTV RRVRAMRPAV QARVDEILDG MLAAGGPVDL 150
    VSAYANAVST SVICELLGIP RHDLEFFRDV TRISGSRNST AEQVSEALGG 200
    LFGLLGGLVA ERREEPRDDL ISKLVTDHLV PGNVTTEQLL STLGITINAG 250
    RETTTSMIAL STLLLLDRPE LPAELRKDPD LMPAAVDELL RVLSVADSIP 300
    LRVAAEDIEL SGRTVPADDG VIALLAGANH DPEQFDDPER VDFHRTDNHH 350
    VAFGYGVHQC VGQHLARLEL EVALETLLRR VPTLRLAGER DQVVVKHDSA 400
    TFGLEELMVT W 411
    Length:411
    Mass (Da):45,100
    Last modified:March 1, 2001 - v1
    Checksum:i7E6F07608BC09B5D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939132 Genomic DNA. Translation: CAC17503.1.
    RefSeqiNP_631725.1. NC_003888.3.

    Genome annotation databases

    EnsemblBacteriaiCAC17503; CAC17503; CAC17503.
    GeneIDi1103124.
    KEGGisco:SCO7686.
    PATRICi23745329. VBIStrCoe124346_7807.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939132 Genomic DNA. Translation: CAC17503.1 .
    RefSeqi NP_631725.1. NC_003888.3.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3TYW X-ray 2.90 A/B/C/D 1-411 [» ]
    4FXB X-ray 2.90 A/B 1-411 [» ]
    ProteinModelPortali Q9EWP1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 100226.SCO7686.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC17503 ; CAC17503 ; CAC17503 .
    GeneIDi 1103124.
    KEGGi sco:SCO7686.
    PATRICi 23745329. VBIStrCoe124346_7807.

    Phylogenomic databases

    HOGENOMi HOG000243678.
    OMAi THNGRRR.
    OrthoDBi EOG6JB11P.
    PhylomeDBi Q9EWP1.

    Family and domain databases

    Gene3Di 1.10.630.10. 1 hit.
    InterProi IPR001128. Cyt_P450.
    IPR002397. Cyt_P450_B.
    IPR017972. Cyt_P450_CS.
    [Graphical view ]
    Pfami PF00067. p450. 1 hit.
    [Graphical view ]
    PRINTSi PR00359. BP450.
    PR00385. P450.
    SUPFAMi SSF48264. SSF48264. 1 hit.
    PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-471 / A3(2) / M145Imported.
    2. "Crystal Structure of CYP105N1 from Streptomyces coelicolor A3(2)."
      Zhao B., Waterman M.R.
      Submitted (SEP-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME.
    3. "Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway."
      Lim Y.R., Hong M.K., Kim J.K., Doan T.T., Kim D.H., Yun C.H., Chun Y.J., Kang L.W., Kim D.
      Arch. Biochem. Biophys. 528:111-117(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME.

    Entry informationi

    Entry nameiQ9EWP1_STRCO
    AccessioniPrimary (citable) accession number: Q9EWP1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2001
    Last sequence update: March 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3