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Protein
Submitted name:

Putative cytochrome P450

Gene

SCO7686

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi360 – 3601Iron (heme axial ligand)Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotationSAAS annotation, Oxidoreductase

Keywords - Ligandi

HemeCombined sources, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative cytochrome P450Imported
Gene namesi
Ordered Locus Names:SCO7686Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO7686.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TYWX-ray2.90A/B/C/D1-411[»]
4FXBX-ray2.90A/B1-411[»]
ProteinModelPortaliQ9EWP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000243678.
InParanoidiQ9EWP1.
OMAiKSIANRD.
OrthoDBiEOG6JB11P.
PhylomeDBiQ9EWP1.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00359. BP450.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9EWP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPPESPTAS HTPGATPPRD FPIQRGCPFA APAEYAALRT DDPVARVTLP
60 70 80 90 100
TRREAWVVTR YDDVRELLSD PRVSADIRRP GFPALGEGEQ EAGARFRPFI
110 120 130 140 150
RTDAPEHTRY RRMLLPAFTV RRVRAMRPAV QARVDEILDG MLAAGGPVDL
160 170 180 190 200
VSAYANAVST SVICELLGIP RHDLEFFRDV TRISGSRNST AEQVSEALGG
210 220 230 240 250
LFGLLGGLVA ERREEPRDDL ISKLVTDHLV PGNVTTEQLL STLGITINAG
260 270 280 290 300
RETTTSMIAL STLLLLDRPE LPAELRKDPD LMPAAVDELL RVLSVADSIP
310 320 330 340 350
LRVAAEDIEL SGRTVPADDG VIALLAGANH DPEQFDDPER VDFHRTDNHH
360 370 380 390 400
VAFGYGVHQC VGQHLARLEL EVALETLLRR VPTLRLAGER DQVVVKHDSA
410
TFGLEELMVT W
Length:411
Mass (Da):45,100
Last modified:March 1, 2001 - v1
Checksum:i7E6F07608BC09B5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939132 Genomic DNA. Translation: CAC17503.1.
RefSeqiNP_631725.1. NC_003888.3.
WP_011031831.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAC17503; CAC17503; CAC17503.
GeneIDi1103124.
KEGGisco:SCO7686.
PATRICi23745329. VBIStrCoe124346_7807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939132 Genomic DNA. Translation: CAC17503.1.
RefSeqiNP_631725.1. NC_003888.3.
WP_011031831.1. NC_003888.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3TYWX-ray2.90A/B/C/D1-411[»]
4FXBX-ray2.90A/B1-411[»]
ProteinModelPortaliQ9EWP1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO7686.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC17503; CAC17503; CAC17503.
GeneIDi1103124.
KEGGisco:SCO7686.
PATRICi23745329. VBIStrCoe124346_7807.

Phylogenomic databases

HOGENOMiHOG000243678.
InParanoidiQ9EWP1.
OMAiKSIANRD.
OrthoDBiEOG6JB11P.
PhylomeDBiQ9EWP1.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00359. BP450.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145Imported.
  2. "Crystal Structure of CYP105N1 from Streptomyces coelicolor A3(2)."
    Zhao B., Waterman M.R.
    Submitted (SEP-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME.
  3. "Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway."
    Lim Y.R., Hong M.K., Kim J.K., Doan T.T., Kim D.H., Yun C.H., Chun Y.J., Kang L.W., Kim D.
    Arch. Biochem. Biophys. 528:111-117(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME.

Entry informationi

Entry nameiQ9EWP1_STRCO
AccessioniPrimary (citable) accession number: Q9EWP1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: July 22, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.