ID   Q9EWN0_STRCO            Unreviewed;       531 AA.
AC   Q9EWN0;
DT   01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2001, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   SubName: Full=DNA-binding protein {ECO:0000313|EMBL:CAC14487.1};
GN   OrderedLocusNames=SCO7759 {ECO:0000313|EMBL:CAC14487.1};
GN   ORFNames=SC5E9.07 {ECO:0000313|EMBL:CAC14487.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAC14487.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAC14487.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939132; CAC14487.1; -; Genomic_DNA.
DR   RefSeq; NP_631792.1; NC_003888.3.
DR   AlphaFoldDB; Q9EWN0; -.
DR   STRING; 100226.gene:17765418; -.
DR   PaxDb; 100226-SCO7759; -.
DR   PATRIC; fig|100226.15.peg.7880; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_8_11; -.
DR   InParanoid; Q9EWN0; -.
DR   OrthoDB; 118142at2; -.
DR   PhylomeDB; Q9EWN0; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000313|EMBL:CAC14487.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT   DOMAIN          122..283
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
FT   DOMAIN          303..517
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   531 AA;  58004 MW;  C2660472623AC593 CRC64;
     MLGRRAEELV GQDAHELLHR GAQGQPLHVS QCAMRQAFHA GHPAQGDDDY FAHADGSVLP
     VSWFIAPYAV DGRNVGTLVL FHPRPQASAT GPHPERTAEP LSELERLALL AETTTRLTST
     LNVDEALHRL VELVLPRLAD WAVIDLITEH DEVWRTAVVH SEEERLVPYE ELQGPMPPVP
     EHSAMPLSRA LRGVASALVE PDVYDRPPDS GIAVEQRRLF DATGIRSAVV VPLRGTREVL
     GAFTLGRTQK QGNFTTADLP LIEDIARRAS LALDNARLYQ RQRAVAETMQ NHLLPQMPRV
     PGLQLAVRYL PAPDASQVGG DWYDAFSLSD GATALAIGDV VGHDLEATAG MAQLRNMLRA
     YAWSQQTPPS RIVERLDEAI MPITDVTMAT LICARVTRTD SGRWHLTWTN AGHPPPLLVT
     RDGLTEYLTD GHSLLLGTGL GSRRPDATVV LPPGCTLLLY TDGLIEVPGQ TLDEGLDRLQ
     QHAAALAHRP LPSFTDQLLR RVQPPGLDDV ALLALRTPKE PLSRKAADTL G
//