Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit omega

Gene

rpoZ

Organism
Thermus aquaticus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.1 Publication

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit omega (EC:2.7.7.6)
Short name:
RNAP omega subunit
Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega
Gene namesi
Name:rpoZ
OrganismiThermus aquaticus
Taxonomic identifieri271 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 9998DNA-directed RNA polymerase subunit omegaPRO_0000129002Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Protein-protein interaction databases

STRINGi498848.TaqDRAFT_5016.

Structurei

Secondary structure

1
99
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 116Combined sources
Beta strandi13 – 164Combined sources
Helixi17 – 3216Combined sources
Turni33 – 375Combined sources
Turni42 – 443Combined sources
Beta strandi51 – 533Combined sources
Helixi60 – 689Combined sources
Turni69 – 713Combined sources
Beta strandi73 – 786Combined sources
Helixi82 – 854Combined sources
Turni86 – 894Combined sources
Beta strandi91 – 933Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HQMX-ray3.30E1-99[»]
1I6VX-ray3.30E1-99[»]
1L9UX-ray4.00E/N1-99[»]
1L9ZX-ray6.50E1-99[»]
1YNJX-ray3.20K1-99[»]
1YNNX-ray3.30K1-99[»]
4XLNX-ray4.00E/K1-99[»]
4XLPX-ray4.00E/K1-99[»]
4XLQX-ray4.60E/K1-99[»]
4XLRX-ray4.30E/K1-99[»]
4XLSX-ray4.01E/K1-99[»]
ProteinModelPortaliQ9EVV4.
SMRiQ9EVV4. Positions 1-98.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9EVV4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG41079SJ. Bacteria.
COG1758. LUCA.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ. 1 hit.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SMARTiSM01409. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9EVV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEPGIDKLF GMVDSKYRLT VVVAKRAQQL LRHRFKNTVL EPEERPKMRT
60 70 80 90
LEGLYDDPNA VTWAMKELLT GRLFFGENLV PEDRLQKEME RLYPTEEEA
Length:99
Mass (Da):11,625
Last modified:January 23, 2007 - v3
Checksum:i1BEC4908DB29CBF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ295839 Genomic DNA. Translation: CAC15848.1.
RefSeqiWP_053767593.1. NZ_LHCI01000106.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ295839 Genomic DNA. Translation: CAC15848.1.
RefSeqiWP_053767593.1. NZ_LHCI01000106.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HQMX-ray3.30E1-99[»]
1I6VX-ray3.30E1-99[»]
1L9UX-ray4.00E/N1-99[»]
1L9ZX-ray6.50E1-99[»]
1YNJX-ray3.20K1-99[»]
1YNNX-ray3.30K1-99[»]
4XLNX-ray4.00E/K1-99[»]
4XLPX-ray4.00E/K1-99[»]
4XLQX-ray4.60E/K1-99[»]
4XLRX-ray4.30E/K1-99[»]
4XLSX-ray4.01E/K1-99[»]
ProteinModelPortaliQ9EVV4.
SMRiQ9EVV4. Positions 1-98.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498848.TaqDRAFT_5016.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG41079SJ. Bacteria.
COG1758. LUCA.

Miscellaneous databases

EvolutionaryTraceiQ9EVV4.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ. 1 hit.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SMARTiSM01409. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOZ_THEAQ
AccessioniPrimary (citable) accession number: Q9EVV4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: January 23, 2007
Last modified: May 11, 2016
This is version 88 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.