Reviewed, UniProtKB/Swiss-Prot Q9EV79 (6PGL_PSEPU)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6PGL
    EC=3.1.1.31

Gene names

Name:

pgl

Organism

Pseudomonas putida

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.
Sequence similarities	Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	6-phosphogluconolactonase		PRO_0000090103

Sequences

	Sequence		Length	Mass (Da)
	Q9EV79-1 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 70F10B7CF5296AC9	FASTA	242	25,322
	10 20 30 40 50 60 MGGRGMGISE LKLPAAVKVH ELADAKTLAA TLAHDVAERL RAAIAAKGQA CVVLSGGRSP 70 80 90 100 110 120 VPFLEKLASE PLDWAKVTVS LADERWVPVE HADSNAGLLA RHLLTGAAAK ARFVGLYQQA 130 140 150 160 170 180 ENLDAAALKA DQALTGLPPI DVLVLGMGDD GHTASLFPAS PNLEAGLDLA STRRCLPLLA 190 200 210 220 230 240 PSVPHQRLSM TRSLLASAAF IALSVQGPGK LATLRAALAG NDLTEMPIRA FLHDPLDIYW CP

References

[1]	"Analysis of the zwf-pgl-eda-operon in Pseudomonas putida strains H and KT2440." Petruschka L., Adolf K., Burchhardt G., Dernedde J., Jurgensen J., Herrmann H. FEMS Microbiol. Lett. 215:89-95(2002) [PubMed: 12393206] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ279003 Genomic DNA. Translation: CAC14909.1.
3D structure databases
SMR	Q9EV79. Positions 24-241.
ModBase	Search...
2-D gel databases
REPRODUCTION-2DPAGE	Q9EV79.
Enzyme and pathway databases
BRENDA	3.1.1.31. 403.
Family and domain databases
InterPro	IPR005900. 6-phosphogluconolactonase. [Graphical view]
PANTHER	PTHR11054. Phosphogluconlac. 1 hit.
TIGRFAMs	TIGR01198. pgl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_PSEPU

Accession

Primary (citable) accession number: Q9EV79

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 24, 2001
Last sequence update:	March 1, 2001
Last modified:	February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)