Q9EV79 (6PGL_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6PGL
EC=3.1.1.31

Gene names

Name:

pgl

Organism

Pseudomonas putida (Arthrobacter siderocapsulatus)

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.
Sequence similarities	Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	6-phosphogluconolactonase		PRO_0000090103

Sequences

	Sequence		Length	Mass (Da)
	Q9EV79 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 70F10B7CF5296AC9	FASTA	242	25,322
	10 20 30 40 50 60 MGGRGMGISE LKLPAAVKVH ELADAKTLAA TLAHDVAERL RAAIAAKGQA CVVLSGGRSP 70 80 90 100 110 120 VPFLEKLASE PLDWAKVTVS LADERWVPVE HADSNAGLLA RHLLTGAAAK ARFVGLYQQA 130 140 150 160 170 180 ENLDAAALKA DQALTGLPPI DVLVLGMGDD GHTASLFPAS PNLEAGLDLA STRRCLPLLA 190 200 210 220 230 240 PSVPHQRLSM TRSLLASAAF IALSVQGPGK LATLRAALAG NDLTEMPIRA FLHDPLDIYW CP

References

[1]	"Analysis of the zwf-pgl-eda-operon in Pseudomonas putida strains H and KT2440." Petruschka L., Adolf K., Burchhardt G., Dernedde J., Jurgensen J., Herrmann H. FEMS Microbiol. Lett. 215:89-95(2002) [PubMed: 12393206] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ279003 Genomic DNA. Translation: CAC14909.1.
3D structure databases
ProteinModelPortal	Q9EV79.
ModBase	Search...
2D gel databases
REPRODUCTION-2DPAGE	Q9EV79.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR005900. 6-phosphogluconolactonase_DevB. IPR006148. Glc/Gal-6P_isomerase. [Graphical view]
Pfam	PF01182. Glucosamine_iso. 1 hit. [Graphical view]
TIGRFAMs	TIGR01198. Pgl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_PSEPU

Accession

Primary (citable) accession number: Q9EV79

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 24, 2001
Last sequence update:	March 1, 2001
Last modified:	September 21, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program