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Q9ETB0 (Q9ETB0_YERPE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 109. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Aspartate-semialdehyde dehydrogenase HAMAP-Rule MF_02121

Short name=ASA dehydrogenase HAMAP-Rule MF_02121
Short name=ASADH HAMAP-Rule MF_02121
EC=1.2.1.11 HAMAP-Rule MF_02121
Alternative name(s):
Aspartate-beta-semialdehyde dehydrogenase HAMAP-Rule MF_02121
Gene names
Name:asd HAMAP-Rule MF_02121 EMBL AAG22007.1
Synonyms:asd2 EMBL AAS63476.1
Ordered Locus Names:y3880 EMBL AAM87425.1, YP_3311 EMBL AAS63476.1, YPO3949 EMBL CAL22530.1
OrganismYersinia pestis [Reference proteome] [HAMAP] EMBL AAG22007.1
Taxonomic identifier632 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding10 – 134NADP By similarity HAMAP-Rule MF_02121
Nucleotide binding37 – 382NADP By similarity HAMAP-Rule MF_02121
Nucleotide binding165 – 1662NADP By similarity HAMAP-Rule MF_02121

Sites

Active site1351Acyl-thioester intermediate By similarity PIRSR PIRSR000148-1 HAMAP-Rule MF_02121
Active site2741Proton acceptor By similarity PIRSR PIRSR000148-1 HAMAP-Rule MF_02121
Binding site731NADP By similarity HAMAP-Rule MF_02121
Binding site1021Phosphate By similarity HAMAP-Rule MF_02121
Binding site1621Substrate By similarity HAMAP-Rule MF_02121
Binding site1931NADP; via carbonyl oxygen By similarity HAMAP-Rule MF_02121
Binding site2411Substrate By similarity HAMAP-Rule MF_02121
Binding site2441Phosphate By similarity HAMAP-Rule MF_02121
Binding site2671Substrate By similarity HAMAP-Rule MF_02121
Binding site3501NADP By similarity HAMAP-Rule MF_02121

Sequences

Sequence LengthMass (Da)Tools
Q9ETB0 [UniParc].

Last modified March 1, 2001. Version 1.
Checksum: EFFEE5C4625B6DE4

FASTA36740,191
        10         20         30         40         50         60 
MKNVGFIGWR GMVGSVLMQR MIEERDFDGI RPVFFSTSQH GQAAPAFAGH QGTLQDAYDI 

        70         80         90        100        110        120 
DALSALDIII TCQGGDYTNQ IYPKLREIGW QGYWIDAASS LRMQDDTIII LDPVNHDVIK 

       130        140        150        160        170        180 
QGLDKGIKTF AGGNCTVSLM LMSLGGLFAN NLVEWASVAT YQAASGGGAR HMRELLTQMG 

       190        200        210        220        230        240 
MLHAGVAKEL QDPASAILDI ERKVTSTTRS GTLPTDNFGV PLAGSLIPWI DKALDNGQSR 

       250        260        270        280        290        300 
EEWKGQAETN KILSTSTLIP VDGLCVRVGA LRCHSQAFTL KLKKDVPLAE IEQMLATHND 

       310        320        330        340        350        360 
WVRVIPNDRE LSMRELTPAA VTGTLNTPVG RLRKLNMGPE YLSAFTVGDQ LLWGAAEPLR 


RMLRILL 

« Hide

References

« Hide 'large scale' references
[1]"Genetic relatedness of Yersinia."
Lindler L.E., Popek M., Huang X.
Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: KIM EMBL AAG22007.1.
[2]"Genome sequence of Yersinia pestis, the causative agent of plague."
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. expand/collapse author list , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.
Nature 413:523-527(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CO-92 / Biovar Orientalis and CO92 EMBL CAL22530.1.
[3]"Genome sequence of Yersinia pestis KIM."
Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. expand/collapse author list , Matson J.S., Blattner F.R., Perry R.D.
J. Bacteriol. 184:4601-4611(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KIM EMBL AAM87425.1 and KIM10+ / Biovar Mediaevalis.
[4]"Annotation and evolutionary relationships of a small regulatory RNA gene micF and its target ompF in Yersinia species."
Delihas N.
BMC Microbiol. 3:13-13(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CO92 EMBL CAL22530.1.
[5]"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. expand/collapse author list , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 91001 EMBL AAS63476.1 and 91001 / Biovar Mediaevalis.
[6]"Genetics of metabolic variations between Yersinia pestis biovars and the proposal of a new biovar, microtus."
Zhou D., Tong Z., Song Y., Han Y., Pei D., Pang X., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R., Du Z., Wang J., Guo Z., Wang J., Huang P., Yang R.
J. Bacteriol. 186:5147-5152(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 91001 EMBL AAS63476.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF282318 Genomic DNA. Translation: AAG22007.1.
AE009952 Genomic DNA. Translation: AAM87425.1.
AE017042 Genomic DNA. Translation: AAS63476.1.
AL590842 Genomic DNA. Translation: CAL22530.1.
PIRAG0480.
RefSeqNP_671174.1. NC_004088.1.
NP_994599.1. NC_005810.1.
YP_002348820.1. NC_003143.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING214092.YPO3949.

Protocols and materials databases

DNASU1148827.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM87425; AAM87425; y3880.
AAS63476; AAS63476; YP_3311.
GeneID1148827.
1176788.
2763780.
KEGGype:YPO3949.
ypk:y3880.
ypm:YP_3311.

Phylogenomic databases

HOGENOMHOG000161376.
KOK00133.
OMALASHNEW.
OrthoDBEOG67X1PS.

Enzyme and pathway databases

BioCycYPES214092:GKDD-3924-MONOMER.
UniPathwayUPA00034; UER00016.
UPA00050; UER00463.
UPA00051; UER00464.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_02121. ASADH.
InterProIPR000319. Asp-semialdehyde_DH_CS.
IPR011534. Asp_ADH_gamma-type.
IPR012080. Asp_semialdehyde_DH.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
PfamPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
PIRSFPIRSF000148. ASA_dh. 1 hit.
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01745. asd_gamma. 1 hit.
PROSITEPS01103. ASD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9ETB0_YERPE
AccessionPrimary (citable) accession number: Q9ETB0
Secondary accession number(s): Q74QZ1, Q7CFY8
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: July 9, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)