Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Putative capacitative calcium entry channel

Gene

trp6

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Putative capacitative calcium entry channelImported
Submitted name:
TRPC6Imported
Gene namesi
Name:trp6Imported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricognathiCaviidaeCavia

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei366 – 38520HelicalSequence analysisAdd
BLAST
Transmembranei405 – 42420HelicalSequence analysisAdd
BLAST
Transmembranei452 – 47019HelicalSequence analysisAdd
BLAST
Transmembranei490 – 50920HelicalSequence analysisAdd
BLAST
Transmembranei596 – 61823HelicalSequence analysisAdd
BLAST
Transmembranei665 – 68622HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000005008.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini67 – 11751ANK_REP_REGIONInterPro annotationAdd
BLAST
Domaini180 – 21233ANK_REP_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili846 – 88136Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the transient receptor (TC 1.A.4) family. [View classification]SAAS annotation
Contains 1 ANK repeat.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotationSAAS annotation, Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3609. Eukaryota.
ENOG410XQ0Y. LUCA.
HOGENOMiHOG000020590.
HOVERGENiHBG068337.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR013555. TRP_dom.
IPR005462. TRPC6_channel.
IPR002153. TRPC_channel.
[Graphical view]
PANTHERiPTHR10117. PTHR10117. 2 hits.
PTHR10117:SF7. PTHR10117:SF7. 2 hits.
PfamiPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
[Graphical view]
PRINTSiPR01097. TRNSRECEPTRP.
PR01647. TRPCHANNEL6.
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 2 hits.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ESX6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDGCPQLPL PPHGYYPSLR GTDNRLTHRR QTVLREKGRR LANRGPAYMF
60 70 80 90 100
NDHSTTLSIE EERFLDAAEY GNIPVVRKML EECLSLNVNC VDYMGQNALQ
110 120 130 140 150
LAVANEHLEI TELLLKKENL SRVGDALLLA ISKGYVRIVE AILSHPAFAE
160 170 180 190 200
GKRLATSPSQ SELQQDDFYA YDEDGTRFSH DVTPIILAAH CQEYEIVHTL
210 220 230 240 250
LRKGARIERP HDYFCKCSEC NQKQKHDSFS HSRSRINAYK GLASPAYLSL
260 270 280 290 300
SSEDPVMTAL ELSNELAVLA NIEKEFKNDY KKLSMQCKDF VVGLLDLCRN
310 320 330 340 350
TEEVEAILNG DVETCQSGDQ GRPNLSRLKL AIKYEVKKFV AHPNCQQQLL
360 370 380 390 400
SIWYENLSGL RQQTMAVKFL VVLGVAIGLP FLALIYWCAP CSKMGKIMRG
410 420 430 440 450
PFMKFVAHAA SFTIFLGLLV MNAADRFEGT KLRPNETSTD NAKQLFRMKT
460 470 480 490 500
SCFSWMEMLI ISWVIGMIWA ECKEIWAQGP KEYLFELWNM LDFGMLAIFA
510 520 530 540 550
ASFIARFMAF WHASKAQSII DANDTLKDLT KVTLGEDVKY YNLARIKWDP
560 570 580 590 600
SDPQIISEGL YAIAVVLSFS RIAYILPANE SFGPLQISLG RTVKDIFKFM
610 620 630 640 650
VIFIMVFVAF MIGMFNLYSY YIGAKQNEAF TTVEESFKTL FWAIFGLSEV
660 670 680 690 700
KSVVINYNHK FIENIGYVLY GVYNVTMVIV LLNMLIAMIN SSFQEIEDDA
710 720 730 740 750
DVEWKFARAK LWFSYFEEGR TLPVPFNLVP SPKSLLYLLL KFKKWGFELF
760 770 780 790 800
QGHKKAFQED AEMNKRNEEK KFGILGSHED LSKLSVDKKQ LGQNKQSSIR
810 820 830 840 850
SSEDFHLNSF NNPPRQYQKI MKRLIKRYVL QAQIDKESDE VNEGELKEIK
860 870 880 890
QDISSLRYEL LEEKSQNTED LAELIRKLGE KLSSEPKQEE INR
Length:893
Mass (Da):102,363
Last modified:March 1, 2001 - v1
Checksum:iA1AD31AE03E1704F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY434717 mRNA. Translation: AAS00088.1.
AJ007017 mRNA. Translation: CAC06051.2.
RefSeqiNP_001166503.1. NM_001173032.2.

Genome annotation databases

GeneIDi100135637.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY434717 mRNA. Translation: AAS00088.1.
AJ007017 mRNA. Translation: CAC06051.2.
RefSeqiNP_001166503.1. NM_001173032.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000005008.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100135637.

Organism-specific databases

CTDi7225.

Phylogenomic databases

eggNOGiKOG3609. Eukaryota.
ENOG410XQ0Y. LUCA.
HOGENOMiHOG000020590.
HOVERGENiHBG068337.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR013555. TRP_dom.
IPR005462. TRPC6_channel.
IPR002153. TRPC_channel.
[Graphical view]
PANTHERiPTHR10117. PTHR10117. 2 hits.
PTHR10117:SF7. PTHR10117:SF7. 2 hits.
PfamiPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
[Graphical view]
PRINTSiPR01097. TRNSRECEPTRP.
PR01647. TRPCHANNEL6.
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
TIGRFAMsiTIGR00870. trp. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 2 hits.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9ESX6_CAVPO
AccessioniPrimary (citable) accession number: Q9ESX6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.