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Q9ESW3

- Q9ESW3_RAT

UniProt

Q9ESW3 - Q9ESW3_RAT

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Protein
Submitted name:

Cytochrome P450

Gene

Cyp1b1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. monooxygenase activity Source: UniProtKB-KW
  4. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450Imported
Gene namesi
Name:Cyp1b1Imported
Synonyms:cyp1b1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2460. Cyp1b1.

Expressioni

Gene expression databases

GenevestigatoriQ9ESW3.

Structurei

3D structure databases

ProteinModelPortaliQ9ESW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG104064.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9ESW3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GLDLEDVPAT ITDIFGASQD TLSTALLWLL ILFTRYPDVQ ARVQAELDQV
60 70 80 90 100
VGRDRLPCMS DQPNLPYVMA FLYESMRFTS FLPVTLPHAT TANTFVLGYY
110 120 130 140 150
IPKNTVVFVN QWSVNHDPAK WSNPEDFDPA RFLDKDGFIN KALASSVMIF
160 170 180 190 200
SVGKRRCIGE ELSKTLLFLF ISILAHQCNF KANQNEPSNM SFSYGLSIKP
210 220 230
KSFKIHVSLR ESMKLLDSAV EKLQAEEACQ
Length:230
Mass (Da):25,939
Last modified:March 1, 2001 - v1
Checksum:i93926541FF8E574C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78583 mRNA. Translation: CAA55320.1.
UniGeneiRn.10125.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78583 mRNA. Translation: CAA55320.1 .
UniGenei Rn.10125.

3D structure databases

ProteinModelPortali Q9ESW3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 2460. Cyp1b1.

Phylogenomic databases

HOVERGENi HBG104064.

Gene expression databases

Genevestigatori Q9ESW3.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
PRINTSi PR00463. EP450I.
PR00385. P450.
SUPFAMi SSF48264. SSF48264. 1 hit.
PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation."
    Bhattacharyya K.K., Brake P.B., Eltom S.E., Otto S.A., Jefcoate C.R.
    J. Biol. Chem. 270:11595-11602(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague DawleyImported.

Entry informationi

Entry nameiQ9ESW3_RAT
AccessioniPrimary (citable) accession number: Q9ESW3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)