Q9ESW2 (Q9ESW2_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
24 proIl-1 alpha EMBL CAC03996.1

Gene names

Name:	Il1a RGD 2890
Synonyms:	IL-1 alpha EMBL CAC03996.1

Organism

Rattus norvegicus (Rat) EMBL CAC03996.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the IL-1 family. RuleBase RU003752

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS020877
Molecular function	Cytokine SAAS SAAS008996
Gene Ontology (GO)
Biological_process	immune response Inferred from electronic annotation. Source: InterPro inflammatory response Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular space Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9ESW2 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 81BA59003CBD295B	FASTA	212	23,990
	10 20 30 40 50 60 MAKVPDLFED LKNCYSENEE YSSAIDHLSL NQKSFYDASY GSLHENCTDK FVSLRTSETS 70 80 90 100 110 120 KMSTFTFKES RVVVSATSNK GKILKKRRLS FNQPFTEDDL EAIAHDLEVK FDMYAYSSGG 130 140 150 160 170 180 DDSKYPVTLK VSNTQLFVSA QGEDKPVLLK EIPETPKLIT GSETDLIFFW EKINSKNYFT 190 200 210 SAAFPELLIA TKEQSQVHLA RGLPSMIDFQ IS

References

[1]	"Production of recombinant rat testis interleukin-1 alpha precursor form and discovery of a novel splice version lacking the calpain cleavage site." Sultana T., Svechnikov K., Weber G., Soeder O. Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Spraque Dawley EMBL CAC03996.1. Tissue: Testis EMBL CAC03996.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ245643 mRNA. Translation: CAC03996.1.
IPI	IPI00192438.
UniGene	Rn.12300.
3D structure databases
ProteinModelPortal	Q9ESW2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9ESW2.
Proteomic databases
PRIDE	Q9ESW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
RGD	2890. Il1a.
Phylogenomic databases
HOGENOM	HOG000113034.
HOVERGEN	HBG002432.
Gene expression databases
ArrayExpress	Q9ESW2.
Genevestigator	Q9ESW2.
Family and domain databases
InterPro	IPR008996. Cytokine_IL1-like. IPR003502. IL1_propep. IPR020877. Interleukin-1_CS. IPR000975. Interleukin_1. IPR003295. InterleukinIL1A. [Graphical view]
PANTHER	PTHR11420. PTHR11420. 1 hit.
Pfam	PF00340. IL1. 1 hit. PF02394. IL1_propep. 1 hit. [Graphical view]
PRINTS	PR00264. INTERLEUKIN1. PR01358. INTRLEUKIN1A.
SMART	SM00125. IL1. 1 hit. [Graphical view]
SUPFAM	SSF50353. Cytok_IL1_like. 1 hit.
PROSITE	PS00253. INTERLEUKIN_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9ESW2_RAT

Accession

Primary (citable) accession number: Q9ESW2

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	October 3, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)