Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

24 proIl-1 alpha

Gene

Il1a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation, MitogenUniRule annotation, PyrogenUniRule annotation
Biological processInflammatory response

Names & Taxonomyi

Protein namesi
Submitted name:
24 proIl-1 alphaImported
Gene namesi
Name:Il1aImported
Synonyms:IL-1 alphaImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2890. Il1a.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9ESW2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 107IL1_propepInterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the IL-1 family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000113034.
HOVERGENiHBG002432.

Family and domain databases

InterProiView protein in InterPro
IPR003295. IL-1_alpha.
IPR020877. IL-1_CS.
IPR000975. IL-1_fam.
IPR003502. IL-1_propep.
IPR008996. IL1/FGF.
PfamiView protein in Pfam
PF00340. IL1. 1 hit.
PF02394. IL1_propep. 1 hit.
PRINTSiPR00264. INTERLEUKIN1.
PR01358. INTRLEUKIN1A.
SUPFAMiSSF50353. SSF50353. 1 hit.
PROSITEiView protein in PROSITE
PS00253. INTERLEUKIN_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ESW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVPDLFED LKNCYSENEE YSSAIDHLSL NQKSFYDASY GSLHENCTDK
60 70 80 90 100
FVSLRTSETS KMSTFTFKES RVVVSATSNK GKILKKRRLS FNQPFTEDDL
110 120 130 140 150
EAIAHDLEVK FDMYAYSSGG DDSKYPVTLK VSNTQLFVSA QGEDKPVLLK
160 170 180 190 200
EIPETPKLIT GSETDLIFFW EKINSKNYFT SAAFPELLIA TKEQSQVHLA
210
RGLPSMIDFQ IS
Length:212
Mass (Da):23,990
Last modified:March 1, 2001 - v1
Checksum:i81BA59003CBD295B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ245643 mRNA. Translation: CAC03996.1.
UniGeneiRn.12300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ245643 mRNA. Translation: CAC03996.1.
UniGeneiRn.12300.

3D structure databases

ProteinModelPortaliQ9ESW2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi2890. Il1a.

Phylogenomic databases

HOGENOMiHOG000113034.
HOVERGENiHBG002432.

Family and domain databases

InterProiView protein in InterPro
IPR003295. IL-1_alpha.
IPR020877. IL-1_CS.
IPR000975. IL-1_fam.
IPR003502. IL-1_propep.
IPR008996. IL1/FGF.
PfamiView protein in Pfam
PF00340. IL1. 1 hit.
PF02394. IL1_propep. 1 hit.
PRINTSiPR00264. INTERLEUKIN1.
PR01358. INTRLEUKIN1A.
SUPFAMiSSF50353. SSF50353. 1 hit.
PROSITEiView protein in PROSITE
PS00253. INTERLEUKIN_1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9ESW2_RAT
AccessioniPrimary (citable) accession number: Q9ESW2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: February 15, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.