Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9ESS9

- Q9ESS9_RAT

UniProt

Q9ESS9 - Q9ESS9_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Gene

Herpud1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cellular calcium ion homeostasis Source: RGD
  2. endoplasmic reticulum unfolded protein response Source: RGD
  3. negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: RGD
  4. positive regulation of protein binding Source: Ensembl
  5. regulation of protein ubiquitination Source: Ensembl
  6. ubiquitin-dependent protein catabolic process Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_100810. ATF4 activates genes.

Names & Taxonomyi

Protein namesi
Submitted name:
Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1Imported
Submitted name:
Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, isoform CRA_aImported
Submitted name:
Protein Herpud1Imported
Submitted name:
SUPImported
Gene namesi
Name:Herpud1Imported
Synonyms:SUPImported
ORF Names:rCG_39087Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 19

Organism-specific databases

RGDi620818. Herpud1.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: MGI
  2. endoplasmic reticulum membrane Source: RGD
  3. integral component of membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9ESS9.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025559.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG259558.
GeneTreeiENSGT00390000017671.
HOGENOMiHOG000252989.
HOVERGENiHBG051899.
KOiK14027.
OMAiLSGDRSW.
OrthoDBiEOG7QRQWK.
TreeFamiTF324319.

Family and domain databases

InterProiIPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ESS9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEPEPQPEPV TLLVKSPNQR HRDLELSGDR GWSVSRLKAH LSRVYPERPR
60 70 80 90 100
PEDQRLIYSG KLLLDHQCLQ DLLPKQEKRH VLHLVCNVRS PSKKPEASTK
110 120 130 140 150
GAESTEQPDN TSQAQYPGDS SSDGLREREV LRNLPPSGWE NVSRPEAVQQ
160 170 180 190 200
TFQGLGPGFS GYTTYGWLQL SWFQQIYARQ YYMQYLAATA ASGAFGPTPS
210 220 230 240 250
AQEIPVVSTP APAPIHNQFP AENQPANQNA AAQAVVNPGA NQNLRMNAQG
260 270 280 290 300
GPLVEEDDEI NRDWLDWTYS AATFSVFLSI LYFYSSLSRF LMVMGATVVM
310 320 330 340 350
YLHHVGWFPF RQRPVQNFPD DGPPQEAANQ DPNNNLQGGL DPEMEDPNRL
360 370 380 390
PVGREVLDPE HTSPSFMSTA WLVFKTFFAS LLPEGPPALA N
Length:391
Mass (Da):43,705
Last modified:March 1, 2001 - v1
Checksum:iFE69D02F3CAA3D1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06097123 Genomic DNA. No translation available.
BC061849 mRNA. Translation: AAH61849.1.
AB033771 mRNA. Translation: BAB16047.1.
CH474006 Genomic DNA. Translation: EDL87344.1.
RefSeqiNP_445975.1. NM_053523.1.
UniGeneiRn.4028.

Genome annotation databases

EnsembliENSRNOT00000025559; ENSRNOP00000025559; ENSRNOG00000018796.
GeneIDi85430.
KEGGirno:85430.
UCSCiRGD:620818. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06097123 Genomic DNA. No translation available.
BC061849 mRNA. Translation: AAH61849.1 .
AB033771 mRNA. Translation: BAB16047.1 .
CH474006 Genomic DNA. Translation: EDL87344.1 .
RefSeqi NP_445975.1. NM_053523.1.
UniGenei Rn.4028.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000025559.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000025559 ; ENSRNOP00000025559 ; ENSRNOG00000018796 .
GeneIDi 85430.
KEGGi rno:85430.
UCSCi RGD:620818. rat.

Organism-specific databases

CTDi 9709.
RGDi 620818. Herpud1.

Phylogenomic databases

eggNOGi NOG259558.
GeneTreei ENSGT00390000017671.
HOGENOMi HOG000252989.
HOVERGENi HBG051899.
KOi K14027.
OMAi LSGDRSW.
OrthoDBi EOG7QRQWK.
TreeFami TF324319.

Enzyme and pathway databases

Reactomei REACT_100810. ATF4 activates genes.

Miscellaneous databases

NextBioi 617534.
PROi Q9ESS9.

Gene expression databases

Genevestigatori Q9ESS9.

Family and domain databases

InterProi IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF00240. ubiquitin. 1 hit.
[Graphical view ]
SMARTi SM00213. UBQ. 1 hit.
[Graphical view ]
SUPFAMi SSF54236. SSF54236. 1 hit.
PROSITEi PS50053. UBIQUITIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: ProstateImported.
  3. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  6. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ9ESS9_RAT
AccessioniPrimary (citable) accession number: Q9ESS9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3