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Protein

Stromal cell-derived factor 2-like protein 1

Gene

Sdf2l1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Stromal cell-derived factor 2-like protein 1
Short name:
SDF2-like protein 1
Gene namesi
Name:Sdf2l1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:2149842. Sdf2l1.

Subcellular locationi

  • Endoplasmic reticulum lumen PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_000003195829 – 221Stromal cell-derived factor 2-like protein 1Add BLAST193

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei215PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9ESP1.
MaxQBiQ9ESP1.
PaxDbiQ9ESP1.
PeptideAtlasiQ9ESP1.
PRIDEiQ9ESP1.
TopDownProteomicsiQ9ESP1.

2D gel databases

REPRODUCTION-2DPAGEiQ9ESP1.

PTM databases

PhosphoSitePlusiQ9ESP1.

Expressioni

Tissue specificityi

Ubiquitously expressed with high expression in the testis, ovary, uterus, and low expression in heart and skeletal muscle.

Inductioni

By tunicamycin and a calcium ionophore, A23187.

Gene expression databases

BgeeiENSMUSG00000022769.
CleanExiMM_SDF2L1.
GenevisibleiQ9ESP1. MM.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi211030. 1 interactor.
IntActiQ9ESP1. 5 interactors.
MINTiMINT-1851587.
STRINGi10090.ENSMUSP00000023453.

Structurei

3D structure databases

ProteinModelPortaliQ9ESP1.
SMRiQ9ESP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 87MIR 1PROSITE-ProRule annotationAdd BLAST55
Domaini95 – 150MIR 2PROSITE-ProRule annotationAdd BLAST56
Domaini151 – 205MIR 3PROSITE-ProRule annotationAdd BLAST55

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi218 – 221Prevents secretion from ERPROSITE-ProRule annotation4

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG3358. Eukaryota.
ENOG410ZBU3. LUCA.
GeneTreeiENSGT00510000046663.
HOGENOMiHOG000236354.
HOVERGENiHBG024385.
InParanoidiQ9ESP1.
OMAiRFQHVGT.
OrthoDBiEOG091G0MFB.
PhylomeDBiQ9ESP1.
TreeFamiTF314557.

Family and domain databases

InterProiView protein in InterPro
IPR027005. GlyclTrfase_39-like.
IPR016093. MIR_motif.
PANTHERiPTHR10050. PTHR10050. 1 hit.
PfamiView protein in Pfam
PF02815. MIR. 1 hit.
SMARTiView protein in SMART
SM00472. MIR. 3 hits.
SUPFAMiSSF82109. SSF82109. 1 hit.
PROSITEiView protein in PROSITE
PS00014. ER_TARGET. 1 hit.
PS50919. MIR. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ESP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWGASRGRVA GPTLLGLLLA LSVRSGGASK ASAGLVTCGS VLKLLNTHHK
60 70 80 90 100
VRLHSHDIKY GSGSGQQSVT GVEESDDANS YWRIRGGSEG GCPRGLPVRC
110 120 130 140 150
GQAVRLTHVL TGKNLHTHHF PSPLSNNQEV SAFGEDGEGD DLDLWTVRCS
160 170 180 190 200
GQHWEREASV RFQHVGTSVF LSVTGEQYGN PIRGQHEVHG MPSANAHNTW
210 220
KAMEGIFIKP GADLSTGHDE L
Length:221
Mass (Da):23,648
Last modified:June 20, 2002 - v2
Checksum:iD2A7C15D360EB25D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB043006 mRNA. Translation: BAB18276.1.
AB043008 Genomic DNA. Translation: BAB18278.1.
BC053425 mRNA. Translation: AAH53425.1.
CCDSiCCDS37270.1.
RefSeqiNP_071719.1. NM_022324.3.
UniGeneiMm.30222.

Genome annotation databases

EnsembliENSMUST00000023453; ENSMUSP00000023453; ENSMUSG00000022769.
GeneIDi64136.
KEGGimmu:64136.
UCSCiuc007ykc.2. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiSDF2L_MOUSE
AccessioniPrimary (citable) accession number: Q9ESP1
Secondary accession number(s): Q9ESP2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: June 20, 2002
Last modified: June 7, 2017
This is version 117 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot