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Q9ESP1 (SDF2L_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Stromal cell-derived factor 2-like protein 1

Short name=SDF2-like protein 1
Gene names
Name:Sdf2l1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Endoplasmic reticulum lumen Potential.

Tissue specificity

Ubiquitously expressed with high expression in the testis, ovary, uterus, and low expression in heart and skeletal muscle.

Induction

By tunicamycin and a calcium ionophore, A23187.

Sequence similarities

Contains 3 MIR domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2828 Potential
Chain29 – 221193Stromal cell-derived factor 2-like protein 1
PRO_0000031958

Regions

Domain33 – 8755MIR 1
Domain95 – 15056MIR 2
Domain151 – 20555MIR 3
Motif218 – 2214Prevents secretion from ER Potential

Sequences

Sequence LengthMass (Da)Tools
Q9ESP1 [UniParc].

Last modified June 20, 2002. Version 2.
Checksum: D2A7C15D360EB25D

FASTA22123,648
        10         20         30         40         50         60 
MWGASRGRVA GPTLLGLLLA LSVRSGGASK ASAGLVTCGS VLKLLNTHHK VRLHSHDIKY 

        70         80         90        100        110        120 
GSGSGQQSVT GVEESDDANS YWRIRGGSEG GCPRGLPVRC GQAVRLTHVL TGKNLHTHHF 

       130        140        150        160        170        180 
PSPLSNNQEV SAFGEDGEGD DLDLWTVRCS GQHWEREASV RFQHVGTSVF LSVTGEQYGN 

       190        200        210        220 
PIRGQHEVHG MPSANAHNTW KAMEGIFIKP GADLSTGHDE L 

« Hide

References

« Hide 'large scale' references
[1]"Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family."
Fukuda S., Sumii M., Masuda Y., Takahashi M., Koike N., Teishima J., Yasumoto H., Itamoto T., Asahara T., Dohi K., Kamiya K.
Biochem. Biophys. Res. Commun. 280:407-414(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Limb.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB043006 mRNA. Translation: BAB18276.1.
AB043008 Genomic DNA. Translation: BAB18278.1.
BC053425 mRNA. Translation: AAH53425.1.
RefSeqNP_071719.1. NM_022324.3.
UniGeneMm.30222.

3D structure databases

ProteinModelPortalQ9ESP1.
SMRQ9ESP1. Positions 35-206.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid211030. 1 interaction.
IntActQ9ESP1. 5 interactions.
MINTMINT-1851587.
STRING10090.ENSMUSP00000023453.

2D gel databases

REPRODUCTION-2DPAGEQ9ESP1.

Proteomic databases

PaxDbQ9ESP1.
PRIDEQ9ESP1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000023453; ENSMUSP00000023453; ENSMUSG00000022769.
GeneID64136.
KEGGmmu:64136.
UCSCuc007ykc.2. mouse.

Organism-specific databases

CTD23753.
MGIMGI:2149842. Sdf2l1.

Phylogenomic databases

eggNOGNOG136457.
GeneTreeENSGT00510000046663.
HOGENOMHOG000236354.
HOVERGENHBG024385.
InParanoidQ9ESP1.
OMASGQHWER.
OrthoDBEOG71VSV4.
TreeFamTF314557.

Gene expression databases

BgeeQ9ESP1.
CleanExMM_SDF2L1.
GenevestigatorQ9ESP1.

Family and domain databases

InterProIPR027005. GlyclTrfase_39_like.
IPR016093. MIR_motif.
[Graphical view]
PANTHERPTHR10050. PTHR10050. 1 hit.
PfamPF02815. MIR. 1 hit.
[Graphical view]
SMARTSM00472. MIR. 3 hits.
[Graphical view]
SUPFAMSSF82109. SSF82109. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS50919. MIR. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSDF2L1. mouse.
NextBio319923.
PROQ9ESP1.
SOURCESearch...

Entry information

Entry nameSDF2L_MOUSE
AccessionPrimary (citable) accession number: Q9ESP1
Secondary accession number(s): Q9ESP2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: June 20, 2002
Last modified: February 19, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot