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Protein
Submitted name:

Melatonin receptor

Gene

Mtnr1a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Melatonin receptorImported
Gene namesi
Name:Mtnr1aImported
Synonyms:MT1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620797. Mtnr1a.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4823HelicalSequence analysisAdd
BLAST
Transmembranei60 – 7819HelicalSequence analysisAdd
BLAST
Transmembranei98 – 11922HelicalSequence analysisAdd
BLAST
Transmembranei140 – 15920HelicalSequence analysisAdd
BLAST
Transmembranei185 – 21127HelicalSequence analysisAdd
BLAST
Transmembranei232 – 25928HelicalSequence analysisAdd
BLAST
Transmembranei271 – 29424HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9ESJ3.
PRIDEiQ9ESJ3.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000034328.

Structurei

3D structure databases

ProteinModelPortaliQ9ESJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 291252G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHFY. Eukaryota.
ENOG4111ZZV. LUCA.
HOVERGENiHBG052528.
PhylomeDBiQ9ESJ3.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002278. Mel_1A_rcpt.
IPR000025. Melatonin_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01149. MELATONIN1AR.
PR00857. MELATONINR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9ESJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LLNASQQAPG GGVEIRSRPS WLASTLAFIL IFTIVVDILG NLLVILSVYR
60 70 80 90 100
NKKLRNAGNI FVASLAVADL VVAIYPFPWA LTSILNNGWN LGYLHCQVSA
110 120 130 140 150
FLMGLSVIGS VFNITGIAMN RYCYICHSLK YDRIYSNKNS LCYVFLIWTL
160 170 180 190 200
TLIAIMPNLQ TGTLQYDPRI YSCTFTQSVS SAYTIALVVF HFVVPMIIVT
210 220 230 240 250
FCYLRIWILV LQVRRRVKPD SKPKLKPQDF RNFVTMFVVF VLFALCWAPL
260 270 280 290 300
NFIGLIVASD PATMAPRIPE WLFVASYYLA YFNSCLNAII YGLLNQNFRK
310 320
EYKRIIISLC TAKMFFVDSS NDAADK
Length:326
Mass (Da):36,911
Last modified:March 1, 2001 - v1
Checksum:i1D69D8CF39A2E59F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei326 – 3261Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF130341 mRNA. Translation: AAG18471.1.
UniGeneiRn.92357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF130341 mRNA. Translation: AAG18471.1.
UniGeneiRn.92357.

3D structure databases

ProteinModelPortaliQ9ESJ3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000034328.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ9ESJ3.
PRIDEiQ9ESJ3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi620797. Mtnr1a.

Phylogenomic databases

eggNOGiENOG410IHFY. Eukaryota.
ENOG4111ZZV. LUCA.
HOVERGENiHBG052528.
PhylomeDBiQ9ESJ3.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002278. Mel_1A_rcpt.
IPR000025. Melatonin_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01149. MELATONIN1AR.
PR00857. MELATONINR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9ESJ3_RAT
AccessioniPrimary (citable) accession number: Q9ESJ3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: May 11, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.