Q9ES92 (Q9ES92_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fc gamma receptor III EMBL AAG28520.1

Gene names

Name:

Fcgr3 EMBL AAG28520.1 MGI 95500

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL AAG28520.1
Gene Ontology (GO)
Biological_process	antibody-dependent cellular cytotoxicity Inferred from mutant phenotype PubMed 8769481PubMed 9743367. Source: MGI antigen processing and presentation of exogenous peptide antigen via MHC class I Inferred from mutant phenotype PubMed 11911824. Source: MGI mast cell activation Inferred from direct assay PubMed 8552190. Source: MGI neutrophil chemotaxis Inferred from mutant phenotype PubMed 11420040. Source: MGI phagocytosis, engulfment Inferred from mutant phenotype PubMed 8769481PubMed 9743367PubMed 9834201. Source: MGI phagocytosis, recognition Inferred from mutant phenotype PubMed 8769481PubMed 9743367PubMed 9834201. Source: MGI positive regulation of phagocytosis Inferred from mutant phenotype PubMed 8769481PubMed 9743367PubMed 9834201. Source: MGI positive regulation of tumor necrosis factor biosynthetic process Inferred from mutant phenotype PubMed 10229794. Source: MGI positive regulation of type I hypersensitivity Inferred from direct assay PubMed 8552190. Source: MGI positive regulation of type III hypersensitivity Inferred from mutant phenotype PubMed 8769481. Source: MGI positive regulation of type IIa hypersensitivity Inferred from mutant phenotype PubMed 11911824PubMed 9834201. Source: MGI serotonin secretion Inferred from direct assay PubMed 8552190. Source: MGI
Molecular_function	IgG binding Inferred from mutant phenotype PubMed 9743367PubMed 9834201. Source: MGI IgG receptor activity Inferred from mutant phenotype PubMed 9743367PubMed 9834201. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9ES92 [UniParc]. Last modified March 1, 2001. Version 1. Checksum: 9C8570E032F94730	FASTA	261	30,098
	10 20 30 40 50 60 MFQNAHSGSQ WLLPPLTILL LFAFADRQSA ALPKAVVKLD PPWIQVLKED MVTLMCEGTH 70 80 90 100 110 120 NPGNSSTQWF HNWSSIRSQV QSSYTFKATV NDSGEYRCQM EQTRLSDPVD LGVISDWLLL 130 140 150 160 170 180 QTPQRVFLEG ETITLRCHSW RNKLLNRISF FHNEKSVRYH HYKSNFSIPK ANHSHSGDYY 190 200 210 220 230 240 CKGSLGSTQH QSKPVTITVQ DPATTSSISL VWYHTAFSLV MCLLFAVDTG LYFYVRRNLQ 250 260 TPRDYWRKSL SIRKHQAPQD K

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[2]	"Mouse Fc gamma RIII: identification and characterization of a new allele in C57BL/6 mice." Fossati Jimack L., Boucrot E., Izui S. Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL AAG28520.1.
[3]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[4]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[7]	Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[8]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[9]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAC36696.1. Tissue: Ovary and uterus EMBL BAC36696.1.
[10]	"Involvement of IgG Fc receptor polymorphisms and C5 in susceptibility to collagen-induced arthritis." Andren M., Johanneson B., Alarcon-Riquelme M.E., Kleinau S. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/10 EMBL AAX13975.1 and C57BL/6 EMBL AAX13974.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF197930 mRNA. Translation: AAG28520.1. AY897419 mRNA. Translation: AAX13974.1. AY897420 mRNA. Translation: AAX13975.1. AK077227 mRNA. Translation: BAC36696.1.
IPI	IPI00989948.
UniGene	Mm.22119.
3D structure databases
HSSP	HSSP built from PDB template 2FCB based on UniProtKB P31994.
SMR	Q9ES92. Positions 31-244.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000027964.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:95500. Fcgr3.
Phylogenomic databases
HOVERGEN	HBG051602.
InParanoid	Q9ES92.
Gene expression databases
Genevestigator	Q9ES92.
Family and domain databases
Gene3D	2.60.40.10. 2 hits.
InterPro	IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR003599. Ig_sub. [Graphical view]
SMART	SM00409. IG. 2 hits. [Graphical view]
PROSITE	PS50835. IG_LIKE. 2 hits. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q9ES92_MOUSE

Accession

Primary (citable) accession number: Q9ES92

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2001
Last sequence update:	March 1, 2001
Last modified:	April 3, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)