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Q9ES92

- Q9ES92_MOUSE

UniProt

Q9ES92 - Q9ES92_MOUSE

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Protein
Submitted name: Fc gamma receptor III
Gene
Fcgr3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. IgG binding Source: MGI
  2. IgG receptor activity Source: MGI

GO - Biological processi

  1. Fc-gamma receptor signaling pathway Source: GOC
  2. antibody-dependent cellular cytotoxicity Source: MGI
  3. antigen processing and presentation of exogenous peptide antigen via MHC class I Source: MGI
  4. cell surface receptor signaling pathway Source: MGI
  5. mast cell activation Source: MGI
  6. neutrophil chemotaxis Source: MGI
  7. phagocytosis, engulfment Source: MGI
  8. phagocytosis, recognition Source: MGI
  9. positive regulation of phagocytosis Source: MGI
  10. positive regulation of tumor necrosis factor biosynthetic process Source: MGI
  11. positive regulation of type I hypersensitivity Source: MGI
  12. positive regulation of type III hypersensitivity Source: MGI
  13. positive regulation of type IIa hypersensitivity Source: MGI
  14. regulation of immune response Source: MGI
  15. serotonin secretion Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Enzyme and pathway databases

ReactomeiREACT_196487. FCGR activation.
REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_210240. Role of phospholipids in phagocytosis.

Names & Taxonomyi

Protein namesi
Submitted name:
Fc gamma receptor IIIImported
Gene namesi
Name:Fcgr3Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95500. Fcgr3.

Expressioni

Gene expression databases

GenevestigatoriQ9ES92.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027964.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG051602.
InParanoidiQ9ES92.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ES92-1 [UniParc]FASTAAdd to Basket

« Hide

MFQNAHSGSQ WLLPPLTILL LFAFADRQSA ALPKAVVKLD PPWIQVLKED    50
MVTLMCEGTH NPGNSSTQWF HNWSSIRSQV QSSYTFKATV NDSGEYRCQM 100
EQTRLSDPVD LGVISDWLLL QTPQRVFLEG ETITLRCHSW RNKLLNRISF 150
FHNEKSVRYH HYKSNFSIPK ANHSHSGDYY CKGSLGSTQH QSKPVTITVQ 200
DPATTSSISL VWYHTAFSLV MCLLFAVDTG LYFYVRRNLQ TPRDYWRKSL 250
SIRKHQAPQD K 261
Length:261
Mass (Da):30,098
Last modified:March 1, 2001 - v1
Checksum:i9C8570E032F94730
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF197930 mRNA. Translation: AAG28520.1.
AY897419 mRNA. Translation: AAX13974.1.
AY897420 mRNA. Translation: AAX13975.1.
AK077227 mRNA. Translation: BAC36696.1.
UniGeneiMm.22119.

Genome annotation databases

UCSCiuc007dmy.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF197930 mRNA. Translation: AAG28520.1 .
AY897419 mRNA. Translation: AAX13974.1 .
AY897420 mRNA. Translation: AAX13975.1 .
AK077227 mRNA. Translation: BAC36696.1 .
UniGenei Mm.22119.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000027964.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc007dmy.2. mouse.

Organism-specific databases

MGIi MGI:95500. Fcgr3.

Phylogenomic databases

HOVERGENi HBG051602.
InParanoidi Q9ES92.

Enzyme and pathway databases

Reactomei REACT_196487. FCGR activation.
REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_210240. Role of phospholipids in phagocytosis.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori Q9ES92.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view ]
SMARTi SM00409. IG. 2 hits.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  2. "Mouse Fc gamma RIII: identification and characterization of a new allele in C57BL/6 mice."
    Fossati Jimack L., Boucrot E., Izui S.
    Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
  3. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  10. "Involvement of IgG Fc receptor polymorphisms and C5 in susceptibility to collagen-induced arthritis."
    Andren M., Johanneson B., Alarcon-Riquelme M.E., Kleinau S.
    Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/10Imported and C57BL/6Imported.

Entry informationi

Entry nameiQ9ES92_MOUSE
AccessioniPrimary (citable) accession number: Q9ES92
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: September 3, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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