UniProtKB - Q9ERV8 (Q9ERV8_RAT)
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Protein
Sex-determining region Y protein
Gene
Sry
Organism
Rattus norvegicus (Rat)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 5 – 73 | HMG boxPROSITE-ProRule annotationAdd BLAST | 69 |
GO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
- DNA binding Source: UniProtKB-UniRule
- DNA binding transcription factor activity Source: InterPro
GO - Biological processi
- cell differentiation Source: UniProtKB-KW
- male sex determination Source: InterPro
- sex differentiation Source: UniProtKB-KW
- transcription, DNA-templated Source: UniProtKB-KW
Keywordsi
Molecular function | ActivatorSAAS annotation, Calmodulin-bindingSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation |
Biological process | Differentiation, Sexual differentiationSAAS annotation, Transcription, Transcription regulationSAAS annotation |
Enzyme and pathway databases
Reactomei | R-RNO-3769402. Deactivation of the beta-catenin transactivating complex. |
Names & Taxonomyi
Protein namesi | Recommended name: Sex-determining region Y proteinSAAS annotation |
Gene namesi | |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 3759. Sry. |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationSAAS annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 73 | HMG boxInterPro annotationAdd BLAST | 69 |
Sequence similaritiesi
Belongs to the SRY family.SAAS annotation
Phylogenomic databases
GeneTreei | ENSGT00760000118988. |
HOVERGENi | HBG008712. |
KOi | K09266. |
OrthoDBi | EOG091G0JDD. |
Family and domain databases
Gene3Di | 1.10.30.10. 1 hit. |
InterProi | View protein in InterPro IPR009071. HMG_box_dom. IPR036910. HMG_box_dom_sf. IPR017253. SRY. |
PANTHERi | PTHR10270:SF199. PTHR10270:SF199. 1 hit. |
Pfami | View protein in Pfam PF00505. HMG_box. 1 hit. |
SMARTi | View protein in SMART SM00398. HMG. 1 hit. |
SUPFAMi | SSF47095. SSF47095. 1 hit. |
PROSITEi | View protein in PROSITE PS50118. HMG_BOX_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q9ERV8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEGHVKRPMN AFMVWSRGER RKLAQQNPSM QNSEISKHLG YQWKSLTEAE
60 70 80 90 100
KRPFFQEAQR LKTLHREKYP NYKYQPHRRV KVPQRSYTLQ REVASTKLYN
110 120 130 140 150
LLQWDNNLHT IIYGQDWARA AHQSSKNQKS IYLQPVDIPT GYPLQQKQQH
160
QQQQHVHLQQ QQQQQHQFH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC243442 Genomic DNA. No translation available. AF274872 Genomic DNA. Translation: AAG09809.1. AY157669 Genomic DNA. Translation: AAN37592.1. EU984075 Genomic DNA. Translation: ACI00058.1. FJ168060 Genomic DNA. Translation: ACI29003.1. FJ168067 Genomic DNA. Translation: ACI29010.1. KC215142 Genomic DNA. Translation: AGG39658.1. |
RefSeqi | NP_036904.1. NM_012772.1. |
Genome annotation databases
Ensembli | ENSRNOT00000092902; ENSRNOP00000076001; ENSRNOG00000062090. |
GeneIDi | 25221. |
KEGGi | rno:25221. |
Similar proteinsi
Entry informationi
Entry namei | Q9ERV8_RAT | |
Accessioni | Q9ERV8Primary (citable) accession number: Q9ERV8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2001 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 28, 2018 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |