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Protein
Submitted name:

Thyrotropin-releasing hormone receptor 2

Gene

Trhr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Thyrotropin-releasing hormone receptor 2Imported
Gene namesi
Name:Trhr2Imported
Synonyms:TRH-R2Imported
ORF Names:mCG_14183Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2177284 Trhr2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 48HelicalSequence analysisAdd BLAST26
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21
Transmembranei100 – 122HelicalSequence analysisAdd BLAST23
Transmembranei142 – 161HelicalSequence analysisAdd BLAST20
Transmembranei181 – 208HelicalSequence analysisAdd BLAST28
Transmembranei251 – 268HelicalSequence analysisAdd BLAST18
Transmembranei288 – 311HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000039079

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042575

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 308G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST270

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00700000104070
HOGENOMiHOG000017249
HOVERGENiHBG007549
KOiK04282
OMAiKTPTNCY
OrthoDBiEOG091G08BE
TreeFamiTF326170

Family and domain databases

CDDicd14995 7tmA_TRH-R, 1 hit
InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR002120 TRH_rcpt_1
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01654 TRHRECEPTOR2
PR01846 TRHRFAMILY
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ERT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGPSNVSLV HGDTTLGLPE YKVVSVLLVL LVCTVGIVGN AMVVLVVLTS
60 70 80 90 100
RDMHTPTNCY LVSLALADLI VLLAAGLPNV SDSLVGHWIY GHAGCLGITY
110 120 130 140 150
FQYLGINVSS CSILAFTVER YIAICHPMRA QTVCTVARAR RIIAGIWGVT
160 170 180 190 200
SLYCLLWFFL VDLNVRDNQR LECGYKVSRG LYLPIYLLDF AVFFIAPLLG
210 220 230 240 250
TLVLYGFIGR ILFQSPLSQE AWQKERQSHG QSEGTPGNCS RSKSSMSSRK
260 270 280 290 300
QATRMLAVIV LLFAVLWTPY RTLVLLNSFL ARPFLDPWVL LFCRTCVYTN
310 320 330 340 350
SAINPVIYSL MSQKFRAAFL KLCWCRAAGS QRRAACAPTS NYSAAQETSL
360 370 380
GTEKMQLGSR EVSGPAAAAS LRCQHEPHFS VL
Length:382
Mass (Da):42,051
Last modified:March 1, 2001 - v1
Checksum:iA848539B7FB88990
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591003 Genomic DNA No translation available.
AF283762 mRNA Translation: AAG17712.1
BC117988 mRNA Translation: AAI17989.1
CH466525 Genomic DNA Translation: EDL11673.1
RefSeqiNP_573465.1, NM_133202.2
XP_011246621.1, XM_011248319.2
UniGeneiMm.154808

Genome annotation databases

EnsembliENSMUST00000044123; ENSMUSP00000042575; ENSMUSG00000039079
GeneIDi170732
KEGGimmu:170732
UCSCiuc009nsk.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9ERT2_MOUSE
AccessioniPrimary (citable) accession number: Q9ERT2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: February 28, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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