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Protein
Submitted name:

Protein Trhr2

Gene

Trhr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Trhr2Imported
Submitted name:
Thyrotropin releasing hormone receptor 2Imported
Submitted name:
Thyrotropin-releasing hormone receptor 2Imported
Gene namesi
Name:Trhr2Imported
Synonyms:TRH-R2Imported
ORF Names:mCG_14183Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2177284. Trhr2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4826HelicalSequence analysisAdd
BLAST
Transmembranei60 – 8021HelicalSequence analysisAdd
BLAST
Transmembranei100 – 12223HelicalSequence analysisAdd
BLAST
Transmembranei142 – 16120HelicalSequence analysisAdd
BLAST
Transmembranei181 – 20828HelicalSequence analysisAdd
BLAST
Transmembranei251 – 26818HelicalSequence analysisAdd
BLAST
Transmembranei288 – 31124HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000039079.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042575.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 308270G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00700000104070.
HOGENOMiHOG000017249.
HOVERGENiHBG007549.
KOiK04282.
OMAiYKTISVF.
OrthoDBiEOG091G08BE.
TreeFamiTF326170.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PANTHERiPTHR24243:SF51. PTHR24243:SF51. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01654. TRHRECEPTOR2.
PR01846. TRHRFAMILY.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ERT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGPSNVSLV HGDTTLGLPE YKVVSVLLVL LVCTVGIVGN AMVVLVVLTS
60 70 80 90 100
RDMHTPTNCY LVSLALADLI VLLAAGLPNV SDSLVGHWIY GHAGCLGITY
110 120 130 140 150
FQYLGINVSS CSILAFTVER YIAICHPMRA QTVCTVARAR RIIAGIWGVT
160 170 180 190 200
SLYCLLWFFL VDLNVRDNQR LECGYKVSRG LYLPIYLLDF AVFFIAPLLG
210 220 230 240 250
TLVLYGFIGR ILFQSPLSQE AWQKERQSHG QSEGTPGNCS RSKSSMSSRK
260 270 280 290 300
QATRMLAVIV LLFAVLWTPY RTLVLLNSFL ARPFLDPWVL LFCRTCVYTN
310 320 330 340 350
SAINPVIYSL MSQKFRAAFL KLCWCRAAGS QRRAACAPTS NYSAAQETSL
360 370 380
GTEKMQLGSR EVSGPAAAAS LRCQHEPHFS VL
Length:382
Mass (Da):42,051
Last modified:March 1, 2001 - v1
Checksum:iA848539B7FB88990
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591003 Genomic DNA. No translation available.
AF283762 mRNA. Translation: AAG17712.1.
BC117988 mRNA. Translation: AAI17989.1.
CH466525 Genomic DNA. Translation: EDL11673.1.
RefSeqiNP_573465.1. NM_133202.2.
XP_011246621.1. XM_011248319.1.
UniGeneiMm.154808.

Genome annotation databases

EnsembliENSMUST00000044123; ENSMUSP00000042575; ENSMUSG00000039079.
GeneIDi170732.
KEGGimmu:170732.
UCSCiuc009nsk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591003 Genomic DNA. No translation available.
AF283762 mRNA. Translation: AAG17712.1.
BC117988 mRNA. Translation: AAI17989.1.
CH466525 Genomic DNA. Translation: EDL11673.1.
RefSeqiNP_573465.1. NM_133202.2.
XP_011246621.1. XM_011248319.1.
UniGeneiMm.154808.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042575.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044123; ENSMUSP00000042575; ENSMUSG00000039079.
GeneIDi170732.
KEGGimmu:170732.
UCSCiuc009nsk.1. mouse.

Organism-specific databases

CTDi170732.
MGIiMGI:2177284. Trhr2.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00700000104070.
HOGENOMiHOG000017249.
HOVERGENiHBG007549.
KOiK04282.
OMAiYKTISVF.
OrthoDBiEOG091G08BE.
TreeFamiTF326170.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039079.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PANTHERiPTHR24243:SF51. PTHR24243:SF51. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01654. TRHRECEPTOR2.
PR01846. TRHRFAMILY.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9ERT2_MOUSE
AccessioniPrimary (citable) accession number: Q9ERT2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.