Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Fibroblast growth factor

Gene

Fgf7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. fibroblast growth factor receptor signaling pathway Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Fibroblast growth factorUniRule annotation
Short name:
FGFUniRule annotation
Gene namesi
Name:Fgf7Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi61805. Fgf7.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333UniRule annotationAdd
BLAST
Chaini34 – 185152Fibroblast growth factorUniRule annotationPRO_5001353803Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ9ERN5.

Family & Domainsi

Sequence similaritiesi

Belongs to the heparin-binding growth factors family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

HOVERGENiHBG007580.

Family and domain databases

InterProiIPR008996. Cytokine_IL1-like.
IPR028247. FGF7.
IPR002209. Fibroblast_GF_fam.
IPR028142. IL-1_fam/FGF_fam.
[Graphical view]
PANTHERiPTHR11486. PTHR11486. 1 hit.
PTHR11486:SF20. PTHR11486:SF20. 1 hit.
PRINTSiPR00263. HBGFFGF.
PR00262. IL1HBGF.
SMARTiSM00442. FGF. 1 hit.
[Graphical view]
SUPFAMiSSF50353. SSF50353. 1 hit.
PROSITEiPS00247. HBGF_FGF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9ERN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKWILTRIL PTPLYRSCFH LVCLVGTISL ACNDMSPEQT ATSVNCSSPE
60 70 80 90 100
RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MRNSYNIMEI
110 120 130 140 150
RTVAVGIVAI KGVESEYYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT
160 170 180
YASAKWTHSG GEMFVALNQK GLPVKGKKTK KXXKT
Length:185
Mass (Da):21,342
Last modified:February 28, 2001 - v1
Checksum:i8DBE8364C9222B88
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei185 – 1851Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF295300 mRNA. Translation: AAG31597.1.
UniGeneiRn.98842.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF295300 mRNA. Translation: AAG31597.1.
UniGeneiRn.98842.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi61805. Fgf7.

Phylogenomic databases

HOVERGENiHBG007580.

Gene expression databases

GenevestigatoriQ9ERN5.

Family and domain databases

InterProiIPR008996. Cytokine_IL1-like.
IPR028247. FGF7.
IPR002209. Fibroblast_GF_fam.
IPR028142. IL-1_fam/FGF_fam.
[Graphical view]
PANTHERiPTHR11486. PTHR11486. 1 hit.
PTHR11486:SF20. PTHR11486:SF20. 1 hit.
PRINTSiPR00263. HBGFFGF.
PR00262. IL1HBGF.
SMARTiSM00442. FGF. 1 hit.
[Graphical view]
SUPFAMiSSF50353. SSF50353. 1 hit.
PROSITEiPS00247. HBGF_FGF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel CD44 Splice Variants Associated with Changes in Alternative Splicing of FGFR-2 and Expression of FGF-2, FGF-7, E-Cadherin and Snail."
    Choi J.K.W., Gibbins J.R., Hunter N., Lyons J.G., Tazawa M.Y., Walker D.M.
    Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Dark AgutiImported.

Entry informationi

Entry nameiQ9ERN5_RAT
AccessioniPrimary (citable) accession number: Q9ERN5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 28, 2001
Last sequence update: February 28, 2001
Last modified: February 3, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.